Clinical trials: Psychiatric Disorders
Post Traumatic Stress Disorder
Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)
The objective will be to determine if adding repetitive transcranial magnetic stimulation prior to Cognitive Processing Therapy significantly enhances recovery from hyperarousal symptoms in individuals with combat related post…
- Trial name
- NCT01391832
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Processing Therapy, Repetitive Transcranial Magnet Stimulation (rTMS)
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Opioid-Induced Bowel Dysfunction, Constipation
The Effect of Naldemedine on Opioid-induced Bowel Dysfunction
Opioid-induced bowel dysfunction is a frequent condition during opioid therapy for chronic pain. Indeed, up to 90% of people on opioid treated patients experience constipation.
- Trial name
- NCT06334198
- Testing
- Naldemedine, Tramadol
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asbjørn Mohr Drewes
Opioid-use Disorder, Overdose of Opiate
Patient Reported Outcomes for Opioid Use Disorder
The goal of the project is to build a clinical data research infrastructure that will begin to enhance capacity to use electronic health record (EHR) data and patient reported outcomes measures (PROs) to conduct opioid related…
- Conditions
- Opioid-use Disorder, Overdose of Opiate, Patient Participation
- Trial name
- NCT03985163
- Testing
- Patient Reported Outcomes Electronic Survey
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Yale University
General Anxiety Disorder, Social Anxiety Disorder
A 10 Week Open-Label Pilot Study to Evaluate the Effectiveness and Safety of Memantine(Namenda) as Augmentation Therapy in Patients With Generalized Anxiety Disorder
This study is being conducted to evaluate the safety and effectiveness of memantine Add-On treatment of patients who are currently taking an SNRI or SSRI and who remain anxious and symptomatic despite treatment.
- Trial name
- NCT00411398
- Testing
- Namenda/Memantine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Substance Abuse
Accuracy & Usability Study for Soberlink Cellular Device
This study scope is to validate the accuracy and usability of the Soberlink Cellular Device in comparison to a predicate device, BACtrack S80 Pro.
- Trial name
- NCT02794038
- Testing
- Soberlink Cellular Device, BACtrack S80 Pro
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Soberlink Healthcare LLC
Bipolar Disorder
White Matter in Pediatric Bipolar Disorder: A DTI Study
Fourteen subjects with bipolar disorder and 14 matching healthy controls, aged 6-13, will receive a magnetic resonance imaging (MRI) scan on a 3 Tesla scanner. They will also have a clinical interview, including the KSADS-PL.
- Trial name
- NCT00391235
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Alzheimer Disease
BnH-015B Clinical Trial in Moderate Alzheimer's Disease
BnH-015B is a small molecule compound that targets the GluN2B binding site on NMDA receptors and positively modulates. BnH-015B has shown, through nonclinical trials, to improve symptoms of cognitive decline by regulating the…
- Trial name
- NCT06535308
- Testing
- BnH-015B 5 mg, BnH-015B 10 mg, BnH-015B 20 mg
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- BnH Research
Stroke, Motor Disorder
Effects of Brain Network by Simultaneous Dual-mode Stimulation in Subacute Stroke Patients
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03279640
- Testing
- rTMS on ipsilesional M1, tDCS on contralesional M1
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
ADHD
Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD
Specific Aim 1: As part of a within-subject, two-days, study design, to determine whether acute calcitriol (vs. placebo) pre-treatment is associated with greater amphetamine (Amp)-induced dopamine (DA) release in the caudate…
- Trial name
- NCT03103750
- Testing
- Magnetic Resonance Imaging (MRI), PHNO, calcitriol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy
Cannabis and Polysubstance Use: Response Inhibition and Stress Exposure
The purpose of this Phase I non-therapeutic trial is to examine the neurological effects of cannabis on stress reactivity and inhibition in healthy cannabis users.
- Trial name
- CAPU RISE (NCT05261321)
- Testing
- Cannabis oil with a high ratio of THC to CBD, Cannabis oil with a high ratio of CBD to THC
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anorexia Nervosa, Metabolic Syndrome
Does Metabolic Syndrome Exist in Anorexia Nervosa?
The purpose of this study is to examine whether body fat distribution changes that occur with weight gain in women recovering from anorexia nervosa are transient or persistent, and if they are associated with other features of…
- Trial name
- NCT00271921
- Testing
- Calorie controlled diet
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Behavior, Adaptive, Mental Illness
IPS/Peer Support Intervention in the DTES
Individual placement support (IPS) is an evidence-based supported employment model for people with severe mental illness, designed to achieve employment in mainstream competitive jobs, either part-time or full-time.
- Conditions
- Behavior, Adaptive, Mental Illness, Substance Use
- Trial name
- NCT03748004
- Testing
- IPS/SP, WorkBC
- Where
- 3 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Schizophrenia, Undifferentiated Type
Comparison of the Effects of Aripiprazole and Risperidone on the Pattern of Brain Activation in Schizophrenic Patients
After an initial screening visit, including an assessment of psychiatric disorders, patients stabilized on antipsychotic medication (aripiprazole or risperidone) for at least 6 weeks and control subjects will undergo an…
- Trial name
- NCT01109147
- Testing
- Imagery, pharmacogenetic sampling
- Where
- 2 sites in France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Qualissima
Postpartum Disorder
The Effect of Back Massage Applied to Mothers in the Early Postpartum Period on Parameters
In the literature, there are separate studies on massage, comfort, anxiety, and physiological parameters for massage practice, but there are no studies that measure the physiological parameters of comfort, pain, anxiety, blood…
- Trial name
- NCT06200649
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Alcohol Use Disorder, Alcohol Dependence
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to alcohol cues in individuals with alcohol use disorder.
- Trial name
- NCT03732248
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Mild Cognitive Impairment
Auditory Stimulation of Slow Wave Sleep and Memory in Mild Cognitive Impairment and Older Adults
This study will evaluate the ability of sounds played during slow wave sleep using a phase locked loop algorithm to enhance slow wave sleep and memory in cognitively healthy older adults and in those with amnestic mild cognitive…
- Trial name
- NCT02608840
- Testing
- Auditory stimulation during sleep
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwestern University
PTSD, Anxiety Disorders
Creating Resilient Workplaces Study
The proposed study aims to understand the impact of a 5-Class CBTm Course on variables contributing to workplace resilience among Public Safety Personnel (PSP).
- Conditions
- PTSD, Anxiety Disorders, Depression, Stress Disorders, Posttraumatic
- Trial name
- CReW (NCT04002050)
- Testing
- Cognitive Behavioural Therapy with Mindfulness Course
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Blood Collection
Use of Acupressure, Aromatherapy, and Virtual Reality for Children in During Blood Collection Procedures
This study aims to evaluate the effects of acupressure, music listening, and virtual reality applications, which appeal to the senses of touch, hearing, and sight during blood sampling, on pain, fear, and anxiety levels in…
- Trial name
- NCT07400874
- Testing
- Acupressure, Listening Music, Virtual Reality
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
This study aims to evaluate the efficacy of community-based early detection and targeted interventions, including stem cell therapy and wearable non-invasive brain-computer interface (BCI) devices, for Mild Cognitive Impairment…
- Conditions
- Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis
- Trial name
- MCITestCare (NCT07214974)
- Testing
- Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Noah Tech, Corp.
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