Clinical trials: Psychiatric Disorders
Autism Spectrum Disorder
Flexibility and the Predictive Brain in Autistic Males and Females
The goal of this study is to compare the neural correlates of predictive brain mechanisms during high-level social and non-social flexibility tasks, between autistic and non-autistic males and females.
- Trial name
- FLEX-PREAU (NCT06391684)
- Testing
- Social/non social; predictable vs unpredictable
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Sleep Disorders, Sleep Apnea
Electrocardiography Data Analysis in Sleep Disorders
The objective of this study is to determine if a non-invasive technique, using an innovative analysis of electrocardiogram (ECG) data, would allow for detection of respiratory events during sleep and discrimination between…
- Conditions
- Sleep Disorders, Sleep Apnea, Sleep Disordered Breathing
- Trial name
- Holter (NCT02188498)
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Anxiety, Educational Problems
Effects of Virtual Reality MRI Preparedness
Magnetic resonance imaging is an important and increasingly prevalent imaging modality used in healthcare. Children often find the procedure anxiety provoking causing difficulty in staying still and providing quality images.
- Trial name
- NCT05086263
- Testing
- Pico G2 4k
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Glucose Intolerance, Appetite Disorders
Almond Consumption and Glycemia
This study will examine the effects of almonds consumed by adults with different body fat distributions on indices of carbohydrate and lipid metabolism.
- Conditions
- Glucose Intolerance, Appetite Disorders, Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorder
- Trial name
- NCT03236116
- Testing
- Almonds, Control (no nuts)
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Purdue University
Schizophrenia
Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia
Schizophrenia affects cognition, emotion, and behavior. Neuropsychological assessment enables a better understanding of antipsychotic effectiveness and the brain processes, underlying cognitive functioning in schizophrenia.
- Trial name
- NCT00789906
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- BeerYaakov Mental Health Center
Semantic Dementia
Evaluation of a Transcranial Stimulation With Direct Current on Language Disorders in Semantic Dementia
Within the spectrum of fronto-temporal lobar degeneration (FTLD) semantic dementia (SD) causes profound language dysfunction. SD damages semantic processing typically in the temporal poles (anterior temporal lobes, ATL).
- Trial name
- STIM-SD (NCT03481933)
- Testing
- Transcranial stimulation
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Age-related Hearing Loss, Cognitive Decline
Auditory-Cognitive Dual-Task Intervention for Older Adults With Hearing Loss
Background: Age-related hearing loss (ARHL) is a common and irreversible condition that has been recently associated with cognitive decline and dementia. Hence, if ARHL is treated earlier, the risk of dementia might decrease.
- Conditions
- Age-related Hearing Loss, Cognitive Decline, Loneliness, Social Isolation
- Trial name
- NCT06486285
- Testing
- Auditory-cognitive dual-task training (ACDT)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Insomnia
Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder
Research has established the incidence of insomnia increases with age and the possible causes contributing to sleep problems in the elderly are still being explored and debated.
- Trial name
- NCT00813735
- Testing
- Eszopiclone, Escitalopram
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lehigh Center for Clinical Research
Emotional Trauma, Child Mental Disorder
Reintegration of Children From Institutions in Azerbaijan
To prevent mental health problems among 7-12 children from orphanages reunited with their biological or extended families in Azerbaijan, this study will refine and test three evidence-based intervention approaches (a) family…
- Conditions
- Emotional Trauma, Child Mental Disorder, Child Maltreatment
- Trial name
- NCT05396625
- Testing
- Usual Care, Family Strengthening, Mental Health Screening, Referral and Connection to Services
- Where
- 2 sites in Azerbaijan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Clinical Practice, Virtual Reality
The Effect of a Pre-Clinical Practice Simulation Using Virtual Reality Stress and Anxiety Levels
This study is designed as a randomized controlled trial to examine the effect of simulation practices using virtual reality headsets related to the operating room environment on nursing students' stress and anxiety levels before…
- Conditions
- Clinical Practice, Virtual Reality, Nursing Education, Nursing Students
- Trial name
- NCT06558292
- Testing
- Virtual Reality Group
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Dementia, Caregiver
Artificial Intelligence + Care Coach Intervention
The purpose of this research study is to develop and test an artificial intelligence intervention for emergency department (ED) discharge care transitions experienced by caregivers of older adults with cognitive impairment.
- Conditions
- Dementia, Caregiver, Emergency Department, Artificial Intelligence
- Trial name
- NCT05352399
- Testing
- NeuViCare application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy Volunteers
Cannabis Effects on Electroencephalography
Background: Tetrahydrocannabinol (THC) is a partial CB1/CB2 agonist and causes its pharmacological effects by binding to cannabinoid receptors.
- Trial name
- CEG (NCT04316598)
- Testing
- Cannabis Sativa
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Epilepsy, Anxiety
Phenotypic Exploration During Sensory Stimulation in an Acoustic Chamber
An observational behavioural and neurophysiological study of the effects of controlled sensory stimulation (such as music, for example) on brain function
- Conditions
- Epilepsy, Anxiety, Depression Anxiety Disorder
- Trial name
- EMO-INTRA (NCT07544563)
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Aged 60 Years or Older, Volunteering to Participate in the Study
The Effect of Health Belief Model-Based Education on Knowledge and Behavioral Changes Regarding Dementia in Older Adults
While age is one of the strongest known risk factors for the onset of dementia, dementia is not an inevitable consequence of aging.
- Conditions
- Aged 60 Years or Older, Volunteering to Participate in the Study, Dementia Education, Prevention Intervention
- Trial name
- NCT07505693
- Testing
- 1. Introduction Session: Increasing Perceived Sensitivity, Session 2: Increasing the Perception of Seriousness/Importance, Session 3: Increasing the Perception of Benefit
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2 in Obese
From Skin Fibroblasts to Neural Stem Cells to Investigate in Vitro the Impact of Diabetes on Adult Neurogenesis
Obesity and glucose intolerance or overt diabetes are increasing at an alarming rate in the population, and are bound to become a public health issue and a major cause of disability, loss of independence and high social costs in…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2 in Obese, Diabetes Mellitus Type 2 in Nonobese, Obesity
- Trial name
- NCT05755321
- Testing
- Skin biopsy
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
MCI, Dementia
Validation of the Montreal Cognitive Assessment (MoCA) Version 8.x and MoCA-MIS in Greece.
Objective: The purpose of this study is to assess the psychometric qualities of the Montreal Cognitive Assessment (MoCA) version 8.x in Greek, including the MoCA-MIS.
- Conditions
- MCI, Dementia, Mild Cognitive Impairment (MCI)
- Trial name
- NCT07297121
- Where
- Greece
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
HIV Infections, Drug Abuse
Disulfiram Interactions With HIV Medications: Clinical Implications
The purpose of this study is to determine whether disulfiram might be a safe and effective treatment for cocaine and/or alcohol dependence in patients with HIV disease.
- Trial name
- NCT00878306
- Testing
- Disulfiram, Disulfiram + Efavirenz, Disulfiram + Atazanavir
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Voice Disorders, Muscle Tension Dysphonia
A Study to Evaluate Effects of Gargle Phonation in Voice
The purpose of this study is to assess subjects with muscle tension dysphonia for perceived effort and acoustic effects of gargle phonation compared to baseline and a sham water swallow.
- Conditions
- Voice Disorders, Muscle Tension Dysphonia, Speech Therapy
- Trial name
- NCT04766658
- Testing
- Gargle Phonation, Water swallow
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postpartum
Effect of Different Foot Baths on Postpartum Insomnia and Fatigue
The goal of this clinical trial is to assess if different footbaths works to decrease postpartum fatigue and insomnia. The main questions are: Does peppermint oil footbaths decrease fatigue and insomnia in postpartum period? Does…
- Trial name
- NCT07060755
- Testing
- Peppermint oil footbath, Warm Water Footbath
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Yalova
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