Clinical trials: Psychological Disease
Hypertension, Ventricular Remodeling
Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Patients With Slight Hypertension and Target Organ Damage
Patients with slight increase in blood pressure levels have an increased cardiovascular risk. In particular this has been demonstrated also in subjects with high-normal blood pressure in whom an exaggerated blood pressure…
- Conditions
- Hypertension, Ventricular Remodeling, Erectile Dysfunctions
- Trial name
- NCT00687206
- Testing
- Valsartan 160mg plus HCT 25mg
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Dementia
Dyadic Personalized Home-Based Activity Program for Mild-to-Moderate Dementia Patients Post-Discharge
This interventional study aims to evaluate the efficacy of a dyadic personalized home-based activity program in managing behavioral and psychological symptoms of dementia (BPSD) among home-dwelling people living with…
- Trial name
- NCT07081750
- Testing
- Dyadic personalized home-based activity program intervention, Routine care
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Fujian Medical University
Mental Health, Anxiety
RCT for Latina Mental Health Using Web-Based Apps
This study compares a choice-driven, interactive, evidence-informed storytelling web-based app intervention with links to resources and treatment (Tx) recommendations (made by a character via her blog) and Tx locator, to a…
- Conditions
- Mental Health, Anxiety, Depression, Well-Being, Psychological
- Trial name
- NCT06874790
- Testing
- Catalina, Control webpage
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Stress
Interest in Spirituality and Oncology: Is It An International Phenomenon?
Primary Objective: -To assess correlations between spiritual and religious beliefs and physician burnout using the Work Related Stress Inventory.
- Trial name
- NCT00429117
- Testing
- Survey
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prehabilitation, Knee Osteoarthritis
Effectiveness of a Prehabilitation Program for Hip or Knee Arthroplasty Surgery.
We live in an increasingly aging society in which the incidence of osteoarticular diseases increases, among which osteoarthritis (OA) stands out.
- Conditions
- Prehabilitation, Knee Osteoarthritis, Hip Osteoarthritis, Physical Therapy Modalities
- Trial name
- Preoperative (NCT06721897)
- Testing
- Prehabilitation Program, Non prehabilitation Program
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- University of Jaén
Stress, Depression
Evaluation of the Efficacy and Mechanisms of Change of Compassion Cultivation Training in Medical Students
The aim of this randomized, waitlist controlled trial is to examine the efficacy of the Compassion Cultivation Training (CCT©) in reducing psychological distress (i.e., stress, anxiety and depression) and burnout symptoms while…
- Conditions
- Stress, Depression, Anxiety, Burn Out
- Trial name
- NCT04690452
- Testing
- Compassion Cultivation Training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Sexual Function Disturbances, Myocardial Infarction
Improving Sexual Function After Myocardial Infarction
The study is completely digital. Men and women who recently had an MI will be invited through a written brochure that will be present in all Norwegian departments of cardiology.
- Trial name
- Sex/MI (NCT05312320)
- Testing
- Information film
- Where
- Norway
- Volunteers
- 1,200 people
- Sponsor
- Sorlandet Hospital HF
Multiple Sclerosis
Virtual Reality in Physical Therapy in Multiple Sclerosis
The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS).
- Trial name
- VIREMS (NCT04807738)
- Testing
- Neuroproprioceptive "facilitation and inhibition" in virtual reality, Neuroproprioceptive "facilitation and inhibition"
- Where
- 2 sites in Czechia
- Volunteers
- 71 people
- Sponsor
- Charles University, Czech Republic
Erectile Dysfunction
Treatment of Erectile Dysfunction II
Randomized, placebo-controlled, double-blind, parallel design, Phase 3 study to evaluate the safety and efficacy of udenafil, an orally administered, potent and selective inhibitor of PDE-5 versus placebo for the treatment of…
- Trial name
- NCT01037218
- Testing
- Udenafil
- Where
- 40 sites in United States
- Volunteers
- 601 people
- Sponsor
- Warner Chilcott
Depression, Anxiety
Glycemic Index/ Load and Mental Disorders
A total of 300 adults would be included in the present cross-sectional study. glycemic index (GI) and glycemic load (GL) would be assessed by using a validated self-administered dish-based semi-quantitative food frequency…
- Conditions
- Depression, Anxiety, Psychological Distress
- Trial name
- NCT02362113
- Testing
- GI/GL
- Volunteers
- 3,000 people
- Sponsor
- Isfahan University of Medical Sciences
Cerebral Palsy, Gait Disorders, Neurologic
Feedback in Augmented Reality to Control of Gait Parameters in Children With Cerebral Palsy
Cerebral palsy (CP) describes a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non progressive disturbances that occurred in the developing fetal or…
- Conditions
- Cerebral Palsy, Gait Disorders, Neurologic, Feedback, Psychological
- Trial name
- BestOf_ARRoW (NCT04460833)
- Testing
- Feedback modalities given through an augmented reality headset
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Fondation Ellen Poidatz
Depression, Stress Disorders, Post-Traumatic
Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms
It is important to provide support and resources for the many post-9/11 Veterans with mental health symptoms and poor psychosocial functioning who do not engage in psychotherapy.
- Trial name
- NCT07202325
- Testing
- Resilience Training for Veterans (REST-V), Usual resources
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- VA Office of Research and Development
Vasculogenic Erectile Dysfunction
Safety and Efficacy Associated With Treating Erectile Dysfunction Patients With Low Intensity Shockwaves by Renova
This is a prospective, randomized, double-blind clinical study comparing safety and efficacy of the treatments performed with the Low Intensity Extracorporeal Shockwave Therapy (LI-ESWT) device - "Renova" on symptomatic ED…
- Trial name
- NCT01811797
- Testing
- Low Intensity Shockwave by Renova
- Where
- Israel
- Volunteers
- 2 people
- Sponsor
- Initia
Stress Disorders, Post-Traumatic, Myocardial Infarction
Myocardial Infarction - Stress Prevention Intervention
Posttraumatic Stress Disorder (PTSD) is a mental disorder that may occur after someone experiences a traumatic event. Between 10-20% of patients may develop PTSD in response to the traumatic experience of myocardial infarction…
- Trial name
- MI-SPRINT (NCT01781247)
- Testing
- Minimal behavioral intervention, Control intervention
- Where
- Switzerland
- Volunteers
- 190 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Genetic Predisposition to Disease
Breast Cancer Risk After Diagnostic Gene Sequencing
Study of the psychological impact of breast cancer risk communication in Cancer Genetics based on the personalized estimation of the BOADICEA V5/PLUS model ("Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation…
- Trial name
- BRIDGEScohort2 (NCT04145817)
- Testing
- BRIDGES gene panel testing, Breast cancer risk polygenic risk score (PRS), Questionnaires
- Where
- 2 sites in France, Germany
- Volunteers
- 405 people
- Sponsor
- Institut Curie
Schizophrenia
Mental Health During the Whole Life Cycle of Community Patients With Schizophrenia
Schizophrenia is one of the components of severe mental disorders. It has the characteristics of prolonged course, low cure rate, high recurrence rate and high disability rate.
- Trial name
- NCT05159349
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Mental Health Center
Inflammatory Bowel Diseases
Mindfulness-based Cognitive Therapy for Patients With Inflammatory Bowel Disease
Considering the limited availability of psychosocial interventions for IBD, this study aims to investigate MBCT as an adjunctive treatment to treatment as usual to reduce psychological stress and improve sleep quality/regularity…
- Trial name
- NCT04646785
- Testing
- Mindfulness-based cognitive therapy + TAU, Treatment as usual (TAU)
- Where
- 4 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Radboud University Medical Center
Vulvodynia, Dyspareunia
Therapy to Prevent Sexual Pain in Breast Cancer Survivors
The purpose of this protocol is to determine whether pain with sexual intercourse can be reduced in menopausal, breast cancer survivors and to evaluate the effectiveness of a non-hormonal therapy (Lidocaine Liquid) vs.
- Conditions
- Vulvodynia, Dyspareunia, Breast Cancer, Menopause
- Trial name
- NCT01539317
- Testing
- Topical liquid lidocaine, Topical saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OHSU Knight Cancer Institute
Depression, Family Dynamics
The Mental Health Effects of a Mindfulness App in Parents of a Child With Medical Complexity
The number of children with special health care needs (CSHCN) in the US is nearly 20% of children representing approximately 14.6 million children nationally.
- Conditions
- Depression, Family Dynamics, Stress, Psychological, Chronic Illness
- Trial name
- NCT05925868
- Testing
- mindfulness app
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Boise State University
Generalised Anxiety Disorder
Trial of Sertraline Versus Cognitive Behaviour Therapy for Generalised Anxiety
Generalised Anxiety Disorder (GAD) is common, causes unpleasant symptoms and impairs people's functioning. It is often chronic and may be accompanied by depression and other anxiety disorders.
- Trial name
- ToSCA (NCT02347033)
- Testing
- Sertraline, Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University College, London
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