Clinical trials: Psychological Disorders
Erectile Dysfunction
Combination Therapy of Tadalafil 2.5mg Plus Sildenafil 25mg Versus Tadalafil 5 mg Monotherapy for Treatment of Erectile Dysfunction: A Randomized, Placebo-Controlled Double-Blinded Cross-Over Study
Erectile dysfunction (ED) is characterized by the persistent inability to attain or sustain an erection adequate for satisfactory sexual intercourse.
- Trial name
- NCT07177326
- Testing
- Tadalafil 2.5 mg, Sildenafil 25 mg, Tadalafil 5 mg
- Volunteers
- 142 people
- Sponsor
- Assiut University
Major Depressive Episode, ECT
Metabolomics During ElectroConvulsivoTherapy
Investigators will measure the variation of blood Metabolome through 1H NMR at several time points during the course of electroconvulsivetherapy in patients with a major depressive episode.
- Trial name
- METECT (NCT05973643)
- Testing
- Electroconvulsive therapy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hôpital le Vinatier
Caregiver Distress
Reducing Distress in Phase 1 Trial Caregivers: The P1-CaLL Study
This study seeks to decrease distress in the lives of the caregivers who are helping cancer patients who have entered a phase 1 clinical trial.
- Trial name
- NCT03557515
- Testing
- Stress Management and CBT, Stress Management and Metta-Meditation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcohol Dependence
A Randomized Clinical Trial of Alcohol Care Management
A randomized study of Alcohol Care Management for the treatment of alcohol dependence in primary care settings.
- Trial name
- NCT00419315
- Testing
- Alcohol Care Management, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 163 people
- Sponsor
- US Department of Veterans Affairs
Tonsil Hypertrophy
Effect of the Combination of Dexamethasone and BIS Monitoring on Reducing Postoperative Nausea and Vomiting in Children
This study will investigate the impact of combining dexamethasone and bispectral index (BIS) monitoring on the incidence of postoperative nausea and vomiting, emergence delirium and recovery trajectories in children undergoing…
- Trial name
- BISDEX (NCT07299435)
- Testing
- BIS monitoring
- Where
- 5 sites in Czechia
- Volunteers
- 1,508 people
- Sponsor
- University Hospital Ostrava
COPD, Non-invasive Ventilation
NIV Reduces CBF in COPD Patients Without Cognitive Function
Objectives: Investigate the acute NIV effects on CBF and cognitive functions in COPD patients. Methods: Nine non-hypercapnic stable COPD subjects (FEV1/FVC < lower limit of normal) and twelve healthy controls were enrolled.
- Conditions
- COPD, Non-invasive Ventilation, Cognitive Impairment, Cerebral Blood Flow
- Trial name
- NCT03149835
- Testing
- Non-invasive ventilation
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Ceara
Anxiety
Management of Anxiety in Intensive Care Unit Including Olfactotherapy
The OCEAN observational study is a pilot study. The aim is to validate the interest of the intervention of essential oils, relaxing music and dim light on the anxiety of patient who are in the intensive care unit.
- Trial name
- OCEAN (NCT04210635)
- Testing
- ZEN cart
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Laboratoires Arkopharma
Post Traumatic Stress Disorders, Burns
Cranial Electrotherapy Stimulation in Burned Patients
To find out if Cranial Electrotherapy Stimulation is a useful treatment for people who have been burned and have Post Traumatic Stress Disorder. CES may be helpful in giving relief to some or all of those symptoms.
- Trial name
- CES (NCT00723008)
- Testing
- Alpha Stim 100 (Cranial Electrotherapy Stimulation)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- United States Army Institute of Surgical Research
Sleep, Physical Activity
Effects of a Wearable Device and Social Media-Based Intervention on Physical Activity and Sleep Quality in Adults
The goal of this randomized controlled trial is to examine whether the use of a wearable device and social media based intention increases physical activity and enhance sleep quality among adults.
- Trial name
- NCT06739876
- Testing
- Wearable device-based intervention (with motivational support via social media), Wearable device-based intervention (without support)
- Where
- Taiwan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Chung Hsing University
Schizophrenia, Bipolar Disorder
Improving Representative Payeeship for People With Psychiatric Disabilities and Their Families
Representative payees, mostly family members, manage Social Security Administration funds of more than one million people with psychiatric disabilities.
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT00924976
- Testing
- Steps for Achieving Financial Empowerment (SAFE)
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- University of North Carolina, Chapel Hill
Alzheimer's Disease
AAB-001 (Bapineuzumab) Open-Label, Long-Term Extension Study in Patients With Mild to Moderate Alzheimer's Disease
This is a multicenter, open-label, long-term extension study in male and female patients with mild to moderate Alzheimer's Disease (AD) who must have completed one of the following studies: AAB-001-201 or AAB-001-102.
- Trial name
- NCT00606476
- Testing
- Bapineuzumab (AAB-001)
- Where
- 29 sites in United States
- Volunteers
- 194 people
- Sponsor
- JANSSEN Alzheimer Immunotherapy Research & Development, LLC
Substance Abuse
Adolescent Substance Abuse: Progressive Treatment
The purpose of this study is to find out more about how to provide effective further treatment for adolescents who have received six weeks of group therapy for substance-use problems and continue to use drugs.
- Trial name
- ADAPT (NCT00680576)
- Testing
- CBT, Cognitive Behavioral Therapy, FFT, Family Functional Therapy
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Major Depressive Disorder
Comparison of Anodal Transcranial Direct Current Stimulation (t-DCS) and Sham Stimulation in Patients With Treatment-resistant Depression
Major depressive disorder (MDD) is a significant public health problem. Existing treatment modalities are not always sufficient to alleviate this disorder. Treatment refractoriness is a common clinical problem.
- Trial name
- NCT02141776
- Testing
- Transcranial direct current stimulation (t-DCS)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Florida
Insomnia, PTSD - Post Traumatic Stress Disorder
Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD
This study is a two-arm individually randomized group treatment clinical trial evaluating behavioral therapies for insomnia, nightmares, and PTSD.
- Conditions
- Insomnia, PTSD - Post Traumatic Stress Disorder, Nightmares
- Trial name
- NCT07069517
- Testing
- Cognitive-Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Written Exposure Therapy (WET)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Palo Alto Veterans Institute for Research
Anxiety
Investigating Predictors of Outcomes From LENS
Anxiety is a very common mental health problem. For people living with anxiety, it can have a huge impact on their lives. There are treatments that can help, such as Cognitive Behavioural Therapy (CBT).
- Trial name
- NCT07339917
- Testing
- Learning Effective New Strategies (LENS)
- Volunteers
- 4,400 people
- Sponsor
- King's College London
Gender Dysphoria
Subcutaneous Testosterone Project
For people who identify as transgender, there is a strong sense that they were born into the wrong body and that their outward looking body does not match how they truly feel about themselves.
- Trial name
- STP (NCT02229617)
- Testing
- Subcutaneous testosterone
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal trial in patients with major…
- Trial name
- CLARITY (NCT07484217)
- Testing
- Solriamfetol 150 MG
- Where
- 40 sites in United States
- Volunteers
- 508 people
- Sponsor
- Axsome Therapeutics, Inc.
Traumatic Brain Injuries, Caregivers
Tidal Model Nursing for TBI Caregivers
Brain injury is a broad concept that may develop as a result of head trauma or surgical interventions, vascular injuries (such as subarachnoid hemorrhage or stroke), metabolic or toxic causes, cerebral anoxia, inflammation, or…
- Conditions
- Traumatic Brain Injuries, Caregivers, Psychological Distress
- Trial name
- Tidal-TBI (NCT07507357)
- Testing
- Tidal Model Based Nursing
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Addiction Opiate, Chronic Pain
Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population
This is a randomized controlled trial. Patients will be randomly assigned to either the control or treatment group, with equal allocation using block randomization.
- Conditions
- Addiction Opiate, Chronic Pain, Fractures, Bone, Buprenorphine Dependence
- Trial name
- SUPER-ERAS (NCT04464512)
- Testing
- Sufentanil
- Where
- United States
- Sponsor
- West Virginia University
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