Clinical trials: Psychological Disorders
Insomnia
A Study To Investigate The Absorption, Metabolism And Excretion Of [14C] PD 0200390 In Six Healthy Male Volunteers
To determine the mass balance of PD 0200390
- Trial name
- NCT00722306
- Testing
- PD 0200390
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Dementia, Alzheimer Disease
Apathy Associated With Alzheimer's Disease
Apathy, or lack of motivation, affects up to 80% of Alzheimer's disease (AD) patients. These amotivational symptoms increase patient reliance on caregivers, increase caregiver burden and distress, and increase the risk of patient…
- Trial name
- NCT00254033
- Testing
- Dextroamphetamine, Methylphenidate
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cognitive Function Abnormal, Diabetes Mellitus, Type 2
Adaptation of a Cognitive Training Intervention for Diabetes Self-Management
The aims of this project are: (1) to refine an existing cognitive rehabilitation intervention and tailor it for persons with T2DM by using current literature and interview data from 10 participants with T2DM and (2) to conduct a…
- Trial name
- NCT03221452
- Testing
- Memory, Attention, and Problem Solving Skills for Diabetes
- Volunteers
- 29 people
- Sponsor
- University of Texas at Austin
Adherence, Tobacco Use Cessation
Smoking Cessation for Young Adults Who Binge Drink - 1
The purpose of this study is develop and test the success of a new smoking cessation intervention that includes a component to eliminate binge drinking.
- Conditions
- Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
- Trial name
- NCT00218452
- Testing
- Lifestyle counseling
- Where
- 3 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cognitive/Functional Effects, Delirium
Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer
RATIONALE: Donepezil and vitamin E may be able to decrease side effects caused by radiation therapy given to prevent brain metastases in patients with small cell lung cancer.
- Conditions
- Cognitive/Functional Effects, Delirium, Depression, Lung Cancer
- Trial name
- NCT00006349
- Testing
- vitamin E, donepezil hydrochloride
- Where
- 15 sites in United States
- Volunteers
- 9 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Primary Insomnia, Depressive Disorders With Insomnia
Enhancing Performance of Cognitive Behavioral Therapy for Insomnia With an Integrative Mobile Platform
Cognitive Behavioral Therapy for Insomnia (CBT-I) has been proven as an effective intervention for the non-pharmacological treatment of insomnia.
- Trial name
- NCT01978626
- Testing
- App modules, Traditional CBT-I
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Hydrocelectomy, Erectile Dysfunction
Assessment of Sexual Function in Male Patients Undergoing Hydrocelectomy and Their Partners
This study aimed to assess changes in sexual function in men undergoing hydrocelectomy and their partners. Male patients who underwent hydrocelectomy in our clinic between 2020 and 2024 were included in the study This study was…
- Conditions
- Hydrocelectomy, Erectile Dysfunction, Sexual Dysfunction Male, Sexual Dysfunction Female
- Trial name
- NCT07069985
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Insomnia Chronic, Insomnia
Effects of Insomnia Treatment on Metabolism in Patients With Depression
This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.
- Conditions
- Insomnia Chronic, Insomnia, Insomnia, Primary, Depression
- Trial name
- NCT04719143
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder
Early Socioemotional Intervention for Children With Autism Spectrum Disorder in Hong Kong and Mainland China
This study aims to develop a culturally-sensitive parent-training intervention to enhance socioemotional functioning of young children (aged 3-6) with Autism Spectrum Disorder (ASD) in Mainland China.
- Trial name
- NCT04658043
- Testing
- Intervention on socioemotional functioning
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- The University of Hong Kong
Diabetes Mellitus, Type 2
Progressive Relaxation Exercise on Sleep Quality in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the effect of progressive relief exercise on sleep quality in patients with type 2 diabetes.
- Trial name
- NCT05956743
- Testing
- progressive relaxation exercise sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Mersin University
Post Partum Depression
Effectiveness of Thinking Healthy Program for Prevention of Antenatal Depression
The trial is to evaluate the effect of an evidence-informed, depression focused early prenatal prevention intervention at six weeks' postpartum.
- Trial name
- PAD (NCT04663243)
- Testing
- Thinking healthy Program sessions designed for antenatal period
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
PTSD
Efficacy of Cervical Sympathetic Blocks for PTSD
Millions of people suffer from anxiety disorders, including posttraumatic stress disorder (PTSD)-a condition that can profoundly disrupt daily life.
- Trial name
- NCT07087015
- Testing
- Cervical sympathetic nerve block, Ropivacaine, Normal Saline
- Volunteers
- 20 people
- Sponsor
- Stanford University
Emotional Distress, Burnout, Professional
A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers
This is a pilot randomized waitlist control trial assessing if the feasibility of using a mobile mindfulness app to treat emotional distress and burnout amongst nurses taking care of COVID-19 patients.
- Conditions
- Emotional Distress, Burnout, Professional, Stress, Job, Anxiety
- Trial name
- LIFT-HCW (NCT04816708)
- Testing
- LIFT Mindfulness
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Duke University
Gender Dysphoria
Gender Identity and Own Body Perception
This study will provide valuable information on the neurobiological underpinning of gender dysphoria (GD) and the effects of sex hormones, and promises to uncover functional or structural neural patterns that could predict…
- Trial name
- NCT04374708
- Testing
- fMRI
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Bipolar Disorder (BD), Bipolar Disorder NOS
Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents
The present study is an open trial of ketogenic diets for adolescents and young adults (ages 12-21 yrs) in the depressive or mixed phases of bipolar disorder (BD).
- Conditions
- Bipolar Disorder (BD), Bipolar Disorder NOS, Bipolar Disorder I or II, Bipolar Spectrum Disorder
- Trial name
- CBN Keto (NCT06920940)
- Testing
- Ketogenic Therapy
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Post-Traumatic Stress Disorder
Cognitive and Emotional Factors in Visual Exploration Among Patients With Post-Traumatic Stress Disorder (SAILLANCE2)
Post-traumatic stress disorder (PTSD) is characterized by hypervigilance. In particular, previous works suggest that patients tend to scan constantly the environment for possible threats.
- Trial name
- SAILLANCE2 (NCT03519789)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Lille
Type 2 Diabetic Patients, Erectile Dysfunction
Prevalence and Risk Factors of Erectile Dysfunction in Type 2 Diabetic Patients
The investigators evaluated 250 male, type 2 diabetic patients, aged 18-80 years. They will undergo IIEF (International Index of Erectile Function), SAS of Zung (self-rating anxiety state)and SDS of Zung (self-rating depression…
- Trial name
- NCT01049750
- Testing
- type 2 diabetic patients
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- University of Pavia
Traumatic Brain Injury, Depression
Life Improvement Following Traumatic Brain Injury
The purpose of this study is to test the effectiveness of a telephone-based and in-person Cognitive Behavioral Therapy (CBT) intervention for treating Major Depressive Disorder (MDD) following Traumatic Brain Injury.
- Trial name
- LIFT (NCT00878150)
- Testing
- In-person Cognitive Behavioral Therapy, Telephone Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Bipolar Disorder, Dyssomnias
Sleep Disturbance and Bipolar Disorder
The study aims to evaluate a psychological intervention for individuals who suffer from sleep disturbance and bipolar disorder. We are hoping that this treatment will: (1) improve the quality of life of individuals with bipolar…
- Trial name
- NCT00993850
- Testing
- Cognitive behavioral therapy for insomnia, Bipolar education
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Berkeley
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