Clinical trials: Psychological Disorders
Post Traumatic Stress Disorder, Traumatic Brain Injury
TMS-fNIRS Personalized Dosing
The intent of this study is to establish technical feasibility in a clinical population (PTSD, with or without mild TBI) of personalized TMS-fNIRS technology.
- Trial name
- NCT05916417
- Testing
- TMS-fNIRS over the dl-PFC
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Florida State University
Stroke, Motor Disorder
Effects of Brain Network by Simultaneous Dual-mode Stimulation in Subacute Stroke Patients
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03279640
- Testing
- rTMS on ipsilesional M1, tDCS on contralesional M1
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Schizophrenia
The Bioequivalence Of Two Different Lurasidone Formulations In Patients
A Phase I, Bioequivalent Study between 2 Formulations of Lurasidone HCl
- Trial name
- NCT01082250
- Testing
- Lurasidone HCl
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Sumitomo Pharma America, Inc.
ADHD
Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD
Specific Aim 1: As part of a within-subject, two-days, study design, to determine whether acute calcitriol (vs. placebo) pre-treatment is associated with greater amphetamine (Amp)-induced dopamine (DA) release in the caudate…
- Trial name
- NCT03103750
- Testing
- Magnetic Resonance Imaging (MRI), PHNO, calcitriol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
Anxiety
Modular Treatment for Preschool Anxiety
This nonrandomized pilot study is investigating the efficacy of a modularized treatment for anxiety in children ages 3-7 years old.
- Trial name
- NCT02510391
- Testing
- PIPA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Adam Lewin
Alzheimer Disease, Cognition Disorders
Investigation Into Delay to Diagnosis of Alzheimer's Disease With Exelon (InDDEx)
This phase IIIb trial is a prospective, randomized, double-blind, placebo-controlled, 36-month study comparing the length of time of progression from mild cognitive impairment (MCI) to a clinical diagnosis of Alzheimer's disease…
- Trial name
- NCT00000174
- Testing
- Rivastigmine
- Where
- 15 sites in United States
- Sponsor
- Novartis
Mood Disorders, Suicide
Investigation on Suicide Risk Factors of Patients With Mood Disorders
This study investigates the level and distribution of suicide risk and learned suicide ability of patients with mood disorders, investigates the related risk factors of suicide and suicide ability formation of patients with mood…
- Trial name
- NCT07523490
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tianjin Anding Hospital
Healthy
Cannabis and Polysubstance Use: Response Inhibition and Stress Exposure
The purpose of this Phase I non-therapeutic trial is to examine the neurological effects of cannabis on stress reactivity and inhibition in healthy cannabis users.
- Trial name
- CAPU RISE (NCT05261321)
- Testing
- Cannabis oil with a high ratio of THC to CBD, Cannabis oil with a high ratio of CBD to THC
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anorexia Nervosa, Metabolic Syndrome
Does Metabolic Syndrome Exist in Anorexia Nervosa?
The purpose of this study is to examine whether body fat distribution changes that occur with weight gain in women recovering from anorexia nervosa are transient or persistent, and if they are associated with other features of…
- Trial name
- NCT00271921
- Testing
- Calorie controlled diet
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Alzheimer Disease, Subjective Cognitive Impairment
Cerebrovascular Reactivity in Alzheimer's Disease
The etiology of Alzheimer's disease (AD), the most common type of dementia, remains largely undefined and the early diagnostic and effective treatments are still not available.
- Trial name
- VARAD-ET (NCT03650816)
- Testing
- Doppler ultrasonography, Biospecimen collection
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder, Depression - Major Depressive Disorder
Mindfulness-based Psilocybin Therapy for PTSD
The goal of this study is to learn how psilocybin delivered with mindfulness-based therapy may help symptoms of posttraumatic stress disorder (PTSD).
- Trial name
- NCT07104916
- Testing
- Psilocybin + MBCT therapy, Active Comparator: Psilocybin with Support Only
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anthony P King
Behavior, Adaptive, Mental Illness
IPS/Peer Support Intervention in the DTES
Individual placement support (IPS) is an evidence-based supported employment model for people with severe mental illness, designed to achieve employment in mainstream competitive jobs, either part-time or full-time.
- Conditions
- Behavior, Adaptive, Mental Illness, Substance Use
- Trial name
- NCT03748004
- Testing
- IPS/SP, WorkBC
- Where
- 3 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Feeding and Eating Disorders
Impact of COVID-19 Lockdown on Obesity and Eating Behaviors
COVID-19 lockdown presents particular challenges for people living with obesity. Indeed during this period, the lifestyle was deeply modified: diet, activity, and sleep behaviours, home office, take care of child, social…
- Trial name
- CIO (NCT04431284)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Hospices Civils de Lyon
Anxiety Disorders, Mental Health
St. John's Wort for the Treatment of Generalized Social Anxiety Disorder (GSAD)
This study will determine whether the herbal product St. John's wort is safe and effective in treating generalized social anxiety disorder (GSAD). Study hypothesis: Hypericum perforatum (St.
- Trial name
- NCT00118833
- Testing
- Hypericum perforatum (St. John's wort)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Acupuncture Therapy, Preoperative Period
Clinical Study of TEAS Intervention in Relieving Anxiety Before Thoracoscopic Surgery
This single-center randomized sham-controlled trial will be conducted in cardiothoracic surgery department of the Yueyang Hospital of Integrated Traditional Chinese and Western Medicine in China.
- Conditions
- Acupuncture Therapy, Preoperative Period, Anxiety, Thoracoscopic Surgery
- Trial name
- NCT04895852
- Testing
- TEAS
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Schizophrenia, Undifferentiated Type
Comparison of the Effects of Aripiprazole and Risperidone on the Pattern of Brain Activation in Schizophrenic Patients
After an initial screening visit, including an assessment of psychiatric disorders, patients stabilized on antipsychotic medication (aripiprazole or risperidone) for at least 6 weeks and control subjects will undergo an…
- Trial name
- NCT01109147
- Testing
- Imagery, pharmacogenetic sampling
- Where
- 2 sites in France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Qualissima
Postpartum Disorder
The Effect of Back Massage Applied to Mothers in the Early Postpartum Period on Parameters
In the literature, there are separate studies on massage, comfort, anxiety, and physiological parameters for massage practice, but there are no studies that measure the physiological parameters of comfort, pain, anxiety, blood…
- Trial name
- NCT06200649
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Depressive Disorder, Major
Effectiveness of Cariprazine Monotherapy for Treatment of Major Depressive Disorder
This trial protocol aims to evaluate the effectiveness and safety of cariprazine monotherapy compared to treatment as usual for major depressive disorder (MDD) in a pragmatic open-label randomized controlled trial (RCT) conducted…
- Trial name
- NCT05933538
- Testing
- Cariprazine, Treatment as usual
- Volunteers
- 110 people
- Sponsor
- Sultan Qaboos University
Alcohol Use Disorder, Alcohol Dependence
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to alcohol cues in individuals with alcohol use disorder.
- Trial name
- NCT03732248
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
ADHD
The Effect of a Brief Educational Intervention for Adults With ADHD
This RCT-study proposes the evaluation of an intensive educational intervention tailored for adults with Attention Deficit Hyperactivity Disorder (ADHD) in community mental health centers (CMHCs).
- Trial name
- NCT06284655
- Testing
- group-based combined with innovative technology education, Standard treatment
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- St. Olavs Hospital
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