Clinical trials: Psychological Disorders
Behavior Problems
Mental Health Services for Toddlers in Foster Care
Toddlers (2- to 3-year-old children) in foster care often have difficulty regulating behavior and biology, and are at risk for a host of mental health problems.
- Trial name
- NCT01261806
- Testing
- Attachment and Biobehavioral Catch-up, Developmental Education for Families
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Healthy
A Study to Assess Effects of Clarithromycin on Pharmacokinetics of JNJ-54861911 in Healthy Male Participants
The purpose of this study is to assess the effects of strong cytochrome P450 (CYP) 3A4 inhibitors (Itraconazole and Clarithromycin), on pharmacokinetics (PK) (study of the way a drug enters and leaves the blood and tissues over…
- Trial name
- NCT02197884
- Testing
- JNJ-54861911, 25 mg, Itraconazole 200 mg, Clarithromycin 500 mg
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Schizophrenia and Disorders With Psychotic Features, Psychotic Episode
Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis (AGES-Mind)
The current investigation aims to compare two group intervention in patients with a first episode of psychosis, that is, people who have suffered their first psychotic episode within 5 years prior to their inclusion in the study.
- Trial name
- AGES-Mind (NCT03309475)
- Testing
- SocialMIND, Psychoeducational multicomponent intervention, Psychosocial treatment
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Dementia, Depression
Geriatric Psychiatry and Pharmacovigilance
The purpose of this observational multicenter-study is to investigate safety of psychopharmacological treatment and rates of adverse drug reactions in gerontopsychiatric inpatients.
- Conditions
- Dementia, Depression, Schizophrenia, Psychosomatic Disorders
- Trial name
- GAP (NCT01858857)
- Where
- 5 sites in Germany
- Volunteers
- 4,000 people
- Sponsor
- Hannover Medical School
Post-traumatic Stress Disorder, Moral Injury
Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure
The aim of this study was to determine the efficacy of Adaptive Disclosure for Moral Injury and Loss (AD-MIL), a combat-specific psychotherapy for war-related PTSD stemming from Moral Injury (MI) and traumatic loss (TL) with Iraq…
- Conditions
- Post-traumatic Stress Disorder, Moral Injury, Traumatic Loss
- Trial name
- NCT03056157
- Testing
- Adaptive Disclosure for Moral Injury and Loss, Present Centered Therapy
- Where
- 5 sites in United States
- Volunteers
- 174 people
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment (MCI), Parkinson Disease (PD)
A Study of CST-2032 in Subjects With Cognitive Impairment
This study will evaluate the effects of CST-2032 when administered with pre-administered CST-107 on safety, tolerability, cognition, cerebral perfusion, and cerebral metabolism in patients with cognitive impairment.
- Trial name
- NCT05033912
- Sponsor
- CuraSen Therapeutics, Inc.
First Episose Psychosis, Metabolic Disease
The ATP Project (Antipsychotic-TEP-Psychosis)
The goal of this observational study is to the early impacts of psychosis and antipsychotic medications on brain metabolism in young adults recently diagnosed with a first episode of psychosis.
- Conditions
- First Episose Psychosis, Metabolic Disease, Psychosis; Episode
- Trial name
- ATP (NCT06651112)
- Testing
- Antipsychotic drugs
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Université de Sherbrooke
Obsessive-compulsive Disorders and Symptoms, Obsessive-Compulsive Disorder
An ERP-based Mobile Intervention as an Adjunctive Treatment for OCD
The objective of this feasibility study is to evaluate the feasibility, acceptability, and potential usefulness of the investigational device, a mobile software application (app) (OC Free) for treatment of OCD (contamination…
- Trial name
- NCT05166707
- Testing
- BIXINK OC Free
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- BIXINK Therapeutics Co., Ltd.
Depression, Anxiety
Low-intensity Stepped Care for Internalizing Distress
The purpose of this study is to test the feasibility and efficacy of combining a single session intervention, COMET, with a self-help intervention, Doing what matters in times of stress. In step I, all individuals receive COMET.
- Conditions
- Depression, Anxiety, Emotion Regulation
- Trial name
- COMET-DWM (NCT05441111)
- Testing
- Common Elements Toolbox, Doing What Matters in Times of Stress: An Illustrated Guide, Guided self-help
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- Indiana University
Polyneuropathy, Alpha-Synucleinopathy
Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System
Description of a method to detect Parkinson's disease or Parkinson's-like disease at an early stage (Prodromal Parkinson's Disease) where damage is still confined to the peripheral nervous system damage.
- Conditions
- Polyneuropathy, Alpha-Synucleinopathy, Lewy Body Disease, Parkinson Disease (PD)
- Trial name
- Prompark (NCT06745011)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Radiation Injuries, Cognitive Impairment
The Effect of Donepezil in Radiotherapy-related Cognitive Impairment.
Purpose: This randomized, double-blind, placebo-controlled clinical trial aims to evaluate the therapeutic effects of donepezil in radiotherapy-related cognitive impairment.
- Trial name
- NCT03907371
- Testing
- Donepezil Hydrochloride
- Where
- China
- Volunteers
- 238 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Alzheimer's Disease
Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease
This is a study to evaluate the efficacy and safety of azeliragon in patients with mild Alzheimer's disease. Patients will receive either azeliragon or placebo with a patient's participation lasting approximately 18 months.
- Trial name
- STEADFAST (NCT02080364)
- Testing
- Azeliragon
- Where
- 115 sites in United States, Australia and 5 more
- Volunteers
- 880 people
- Sponsor
- vTv Therapeutics
Panic; Agoraphobia
Virtual Reality for Panic Disorder With Agoraphobia
Panic disorder with agoraphobia (PDA) is associated with considerable personal distress, functional disability and societal costs.
- Trial name
- NCT03101332
- Testing
- Virtual Reality cognitive behavior therapy
- Where
- 2 sites in Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Substance Dependence
Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809
GSK598809 is being developed as an innovative treatment for substance dependence and potentially other compulsive behavioral disorders.
- Trial name
- NCT00437632
- Testing
- GSK598809, Caffeine
- Where
- United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postoperative Delirium
Automated Pupillometry in Patients Underwent Cardiac Surgery to Predict Postoperative Delirium
The rate of postoperative delirium in patients who underwent cardiac surgery is very high. Different predictors and/or scores were studied for the prediction of Post Operative Delirium (POD)after heart surgery, but none of them…
- Trial name
- NCT06255132
- Testing
- Automated pupillometer NPi-200
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Posttraumatic Stress Disorder
Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD - Israel
The goal of this clinical trial is to learn if MDMA-assisted therapy can treat PTSD in participants with PTSD. Researchers will compare two sessions of MDMA-assisted therapy with two sessions of low dose (active placebo)…
- Trial name
- NCT00402298
- Testing
- Full Dose Midomafetamine HCl, Low Dose Midomafetamine HCl
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Resilient Pharmaceuticals
Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics (NeuroToP - a COPANA Follow up)
Fundamental aspects of both neurological and reproductive function are established in fetal life, and there is a present increased awareness of the potential effects of fetal exposures on neurodevelopmental and reproductive…
- Conditions
- Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction, Developmental Disability, Adhd
- Trial name
- NeuroToP (NCT07316387)
- Where
- Denmark
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Erectile Dysfunction
Clinical Investigation Using MED3000 Gel or Tadalafil Tablets in the Treatment of Erectile Dysfunction
An open-label investigation using MED3000 gel or tadalafil (5 mg) tablets in the treatment of erectile dysfunction in patients from 22 to 70 years of age. Each patients will be expected to participate for up to 30 weeks.
- Trial name
- NCT04984993
- Testing
- MED3000 (Male), Tadalafil 5mg (Male), MED3000 (Female)
- Where
- 18 sites in United States, Bulgaria and 2 more
- Volunteers
- 116 people
- Sponsor
- Futura Medical Developments Ltd.
Veterans Family, Military Family
Family Psychoeducation for Military Veterans: A Pilot Study
Operational Stress Injuries (OSIs), including post traumatic stress disorder (PTSD), are prevalent among veterans deployed in recent combat missions, the effects of which are experienced within their families.
- Conditions
- Veterans Family, Military Family, Trauma, Psychological
- Trial name
- NCT04180293
- Testing
- Pilot psychoeducation program, Program evaluation
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Autistic Disorder
Treatment of Autism in Children and Adolescents
This study is designed to determine the effectiveness of risperidone, a drug treatment for the interfering symptoms of Autistic Disorder in children and adolescents between the ages of 5 and 17.
- Trial name
- NCT00005014
- Testing
- Risperidone
- Where
- 5 sites in United States
- Volunteers
- 101 people
- Sponsor
- National Institute of Mental Health (NIMH)
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