Clinical trials: Psychological Disorders
Attention Deficit-Hyperactivity Disorder
Real World Evidence of the Efficacy and Safety of FOQUEST
This study is a four-month, phase IV, open-label study of ADHD symptomatology and functional outcomes in pediatric (6 to 17 years old) and adult (≥18 years or older) patients with ADHD treated with FOQUEST or VYVANSE.
- Trial name
- reFOQus (NCT04152629)
- Testing
- Methylphenidate Hydrochloride, Lisdexamfetamine Dimesylate
- Where
- 12 sites in Canada
- Volunteers
- 257 people
- Sponsor
- Purdue Pharma, Canada
Borderline Personality Disorder
Mindfulness for Intense Emotions: A Feasibility Trial
This study explores the feasibility of a mindfulness-based intervention for people with a diagnosis of borderline personality disorder.
- Trial name
- MindIE (NCT02849431)
- Testing
- Mindfulness-based intervention
- Where
- United Kingdom
- Sponsor
- Canterbury Christ Church University
Binge-Eating Disorder
Binge Eating Liraglutide Intervention
The study is a 17-week, single-center, double-blind, parallel-group, randomized placebo controlled trial that will test the efficacy of liraglutide 3.0 mg/d as compared to placebo in reducing the number of binge episodes per…
- Trial name
- BELIEVE (NCT03279731)
- Testing
- Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kelly Allison
Dementia, Nursing Homes Residents
Sing Out Loud: A Choral Singing Program for Persons Living With Dementia
This study intends to investigate whether a singing programme for nursing home residents living with dementia can reduce the mental and physiological effects of dementia. The main questions it aims to answer are: 1.
- Trial name
- SOL (NCT06880237)
- Testing
- Singing
- Where
- Singapore
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Psychosis
Strengthening Care in Collaboration With People With Lived Experience of Psychosis in Uganda
Background: Mental health services are most effective and equitable when designed, delivered, and evaluated in collaboration with people with lived experience of mental health conditions.
- Trial name
- SCAPE-U (NCT05863572)
- Testing
- Primary care health worker training, Community Health Workers Training, Home visits
- Where
- Uganda
- Volunteers
- 179 people
- Sponsor
- George Washington University
Psychiatric Disorder
Effect of Vitamin D Supplementation on Mental Health: An Exploratory Study on A University Students Suffering From Vitamin D Deficiency
University students are susceptible to psychological burdens such as depressive symptoms, anxiety, and stress which might have been linked to vitamin D deficiency. Low serum vitamin D level is well recognized around the world.
- Trial name
- NCT06458686
- Testing
- Vit D
- Volunteers
- 70 people
- Sponsor
- German University in Cairo
PTSD
Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder
This study, conducted at the NIH and the Mount Sinai School of Medicine, will examine the effectiveness of a substance P or NK1 antagonist study drug known as GR205171 in treating the symptoms of posttraumatic stress disorder…
- Trial name
- NCT00383786
- Testing
- NK1 Antagoist (GR205171), Psychophysiology (Trauma Script), Psychophysiology (Verbal Threat)
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Baylor College of Medicine
Combat Disorders, Stress Disorders, Post-Traumatic
Quetiapine Augmentation for Treatment-resistant PTSD
The purpose of this study is to compare the response of veterans with PTSD without an optimal response to paroxetine to quetiapine augmentation versus placebo.
- Trial name
- NCT00292370
- Testing
- Open Label (OL) Paroxetine, Quetiapine
- Where
- 3 sites in United States
- Volunteers
- 124 people
- Sponsor
- VA Office of Research and Development
Delivery, Post Partum
Evaluation of Postpartum Posttraumatic Stress Disorder at Angers University Hospital (ESPT-PP)
The purpose of this study is to estimate the prevalence of post-traumatic stress disorder (PTSD) at one month in women who have given birth at the University Hospital of Angers over a period of 1 year.
- Trial name
- ESPT-PP (NCT04160273)
- Testing
- patient questionnaire and telephone follow-up
- Where
- France
- Volunteers
- 1,451 people
- Sponsor
- University Hospital, Angers
Brain Concussion, Brain Trauma
Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)
The proposed study will evaluate a new approach to cognitive rehabilitation of mTBI using a brain stimulation technique called "Remotely Supervised Transcranial Direct Current Stimulation combined with Cognitive Training"…
- Conditions
- Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries
- Trial name
- COGNETRIC (NCT06413173)
- Testing
- Active tDCS and Cognitive Training Intervention
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- United States Naval Medical Center, San Diego
Early Psychosis, Schizophrenia Prodromal
Perception and Integration of Sensory Information in the Early Stages of Psychosis
The goal of this observational study is to investigate the early sensory system in clinical high risk (CHR), first episode psychosis (FEP) individuals and heathly controls.
- Trial name
- PRIOR-ePSY (NCT07446569)
- Testing
- behavioral tasks, Electroretinography, Comprehensive Assessment of At Risk Mental States (CAARMS)
- Where
- 4 sites in France
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Major Depressive Disorder
Assessment of Transcultural Psychotherapy in Child Major Depressive Disorder
The symptomatic and clinical expression of psychiatric disorders in children and adolescents is strongly influenced by the cultural setting they are growing up in.
- Trial name
- EDPT-ADOS (NCT04206969)
- Testing
- Transcultural psychotherapy
- Where
- 4 sites in France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fear, Stress
Epi-Genetic Modulators of Fear Extinction in Alcohol Dependence
Background: Researchers want to learn if people with alcohol dependence have more difficulty learning to feel calm, or learn to fear things more easily.
- Conditions
- Fear, Stress, Alcohol Dependence
- Trial name
- NCT02438969
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Work Related Stress
Validation of an Employee Remote Workplace Stress Measure Embedded Within a Novel Employee Wellbeing App
This study aims to validate an adapted workplace stress scale (American Institute of Stress) for employees working remotely during the COVID-19 pandemic.
- Trial name
- NCT04752683
- Testing
- MyBuddy Employee Wellbeing App
- Volunteers
- 220 people
- Sponsor
- Holly Risdon
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Alcohol Dependence
Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence
The purpose of the study is long-term safety, tolerability and efficacy of nalmefene in patients with alcohol dependence.
- Trial name
- SENSE (NCT00811941)
- Testing
- Nalmefene
- Where
- 60 sites in Czechia, Estonia and 8 more
- Volunteers
- 665 people
- Sponsor
- H. Lundbeck A/S
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Patient Relations, Nurse, Patient Satisfaction
Aromatherapy Methods in Reducing Anxiety Before Breast Biopsy
A breast biopsy is a cause for anxiety for most women when faced with a diagnosis of breast cancer. Physiological and psychological effects of breast biopsy may continue in the pre-biopsy and post-biopsy period.
- Conditions
- Patient Relations, Nurse, Patient Satisfaction, Anxiety State, Breast Cancer
- Trial name
- NCT05276505
- Testing
- Lavender Aromatherapy Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Fibromyalgia, Insomnia
Sleep and Pain Interventions in Women With Fibromyalgia
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia.
- Conditions
- Fibromyalgia, Insomnia, Chronic Widespread Pain
- Trial name
- SPIN-II (NCT03744156)
- Testing
- Cognitive Behavioral Treatment-Insomnia, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Missouri-Columbia
Schizophrenia, Delusional Disorders (ICD-10)
Cognitive Determinants of Psychoeducation and Information in Psychoses
The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can…
- Trial name
- COGPIP (NCT00646256)
- Testing
- COGPACK training, psychoeducation
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- German Research Foundation
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