Clinical trials: Psychological Disorders
Opioid Dependence, Opioid-Related Disorders
Treatment of Opioid Use: Medication Adherence Therapy
To test the feasibility and acceptability of a novel approach for improving the delivery and effectiveness of XRNTX treatment for opioid use disorder (OUD) - the MAT-PLUS intervention.
- Trial name
- MAT-PLUS (NCT03567356)
- Testing
- MAT-PLUS "Helping Hands"
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Potomac Health Foundations
Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease
Addressing Dementia Via Agitation-Centered Evaluation
This is a multi-center, randomized, double-blind, placebo-controlled study, to assess the efficacy and safety of AXS-05 in the treatment of agitation in patients with Alzheimer's disease.
- Conditions
- Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease, Agitation,Psychomotor
- Trial name
- ADVANCE (NCT03226522)
- Testing
- AXS-05, Bupropion
- Where
- 78 sites in United States, Australia
- Volunteers
- 366 people
- Sponsor
- Axsome Therapeutics, Inc.
Dementia
Multidisciplinary Intervention for Challenging Behaviour (Agitation) in Patients With Dementia
The increasing prevalence of dementia is a major challenge to the health authorities in most countries. Nearly all the persons suffering from dementia experience behavioural and psychological symptoms (BPSD).
- Trial name
- TID (NCT01183351)
- Testing
- Psychosocial intervention
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Sykehuset Innlandet HF
Mental Health Disorder
Homeless Population and Mental Health: Impact of Primer la Llar Program
The main goal is to evaluate the impact of the Primer La Llar housing program for the homeless population on the mental health of the participants.
- Trial name
- NCT03622151
- Testing
- Primer la Llar program
- Volunteers
- 86 people
- Sponsor
- Parc Sanitari Sant Joan de Déu
Compassion Fatigue, Burnout
Student Paramedics' Experiences of Compassion Fatigue: a Phenomenological Mixed-methods Study
This study explored how student paramedics experience compassion fatigue - a type of emotional and physical exhaustion that can occur when regularly caring for others in distress.
- Conditions
- Compassion Fatigue, Burnout, Paramedical Professional, Occupational Stress
- Trial name
- NCT06998602
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Teesside University
Alzheimer Disease, Dementia
A Study of the Safety and Effectiveness of Galantamine in Patients With Alzheimer's Disease
The purpose of this study is to evaluate the long-term efficacy and safety of galantamine in patients with Alzheimer's disease.
- Conditions
- Alzheimer Disease, Dementia, Mental Disorders, Brain Diseases
- Trial name
- NCT00216502
- Testing
- galantamine hydrobromide
- Volunteers
- 254 people
- Sponsor
- Janssen-Cilag S.p.A.
Nasal Disease, Agitation, Emergence
Dexmedetomidine and Agitation After Nasal Surgery
The main objective of study is to compare dexmedetomidine single bolus dose before extubation with continuous infusion as regards their efficacy in mitigating the incidence of emergence agitation in obese adults undergoing nasal…
- Trial name
- NCT06867302
- Testing
- Dexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML), Dexmedetomidine Injection [Precedex]
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Physical Exercise
Can Exercise Rewire the Brain Addiction Circuitry?
The aim of the present study is to apply neuroimaging techniques to investigate how physical exercise may influence the addiction circuitry, ultimately reducing alcohol consumption and craving in youth binge drinkers.
- Trial name
- REWIRED (NCT06317753)
- Testing
- Aerobic Exercise, Agility-Cognitive Exercise, Stretching/relaxation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Minho
Elderly Persons
Mandala for Anxiety, Fatigue, and Sleep
Looking at the studies on social activity programs in individuals living in nursing homes in the literature, it was seen that the studies on Mandala therapy were limited.
- Trial name
- MANDALA (NCT07145853)
- Testing
- Mandala activity
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Marmara University
Psychological Stress, Mental Fatigue
A Multi-Dimensional Comparative Study of Exercise Psychological Experience Under AI Fitness Companion and Human Coach Paradigms
This study conducted a comparative analysis of subjective exercise experiences between an AI-based fitness companion and traditional human coaching among 98 university students participating in a standardized 20-minute functional…
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- NCT07690553
- Testing
- AI-Based Companion, Human-Coached
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Mild Cognitive Impairment
Memory Training in Patients With Amnestic Mild Cognitive Impairment
Preview research reports evidence of cognitive plasticity among individuals with amnestic Mild cognitive Impairment, and small-size studies have suggest that this population can benefit from memory training.
- Trial name
- NCT01978353
- Testing
- Memory Training, Psychoeducation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Primary Progressive Aphasia, Frontotemporal Dementia
Communication Bridge Speech Therapy Research Study
This is a study on Internet-based video-practice speech and language therapy for persons with primary progressive aphasia (PPA), behavioral-variant frontotemporal dementia (bvFTD), or related conditions.
- Trial name
- CB (NCT02439853)
- Testing
- Monthly Check-in Session
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Chicago
Elderly, Major Depression
Depression in the Elderly and Cerebral Amyloid Plaques: Characterization by [18F] AV-45 Affectives Symptoms and Amyloïd Plaques (ASAP)
The primary objective of the study is to compare the brain amyloid load in fully, partially and non remitting depressed elderly patients at 8 weeks of antidepressant therapy, by using PET with [F18]AV45.
- Trial name
- ASAP (NCT01962753)
- Testing
- 18FAV45
- Where
- 10 sites in France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Tours
Emotional Disorder
Metabolic Activation of Brain Areas With Emotional Stimuli Compared With Score in Psychological Test
Quantitative assessment of the activation of brain areas by functional magnetic resonance imaging (fRMI) in the face of positive and negative emotional stimuli using audiovisual materials validated for the local population and…
- Trial name
- fMRI (NCT04974437)
- Where
- Argentina
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Instituto del Corazon, Argentina
Pain, Anxiety
The Effect of Virtual Reality Use in Cystoscopy on Pain, Anxiety, and Comfort: A Randomized Controlled Trial
This study aims to evaluate the effects of virtual reality (VR) distraction on pain, anxiety, and comfort levels patients undergoing cystoscopy.
- Conditions
- Pain, Anxiety, Patient Comfort, Cystoscopy
- Trial name
- NCT07872137
- Testing
- Virtual Reality Distraction, Standard Care
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Karamanoğlu Mehmetbey University
Anxiety, Depression
PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness
This is a stepped wedged randomized controlled trial comparing the PARTNER intervention with usual care in 5 Intensive Care Units.
- Trial name
- NCT02445937
- Testing
- PARTNER II
- Where
- 2 sites in United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Tobacco Use Disorder, Lung Cancer
Assessing the Link Between Smoke Carcinogen Biomarkers and Lung Cancer Risk - 1
Lung cancer is the leading cause of cancer death in the United States. Currently it remains impossible to predict which smokers will get cancer. Each puff of a cigarette delivers a mixture of over 60 known carcinogens.
- Trial name
- NCT00218179
- Testing
- Non-intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Mild Cognitive Impairment
Effects of Memory Boot Camp on Brain Function in Adults With Symptoms of Mild Cognitive Impairment (MCI)
This is a prospective controlled clinical trial to determine the effects of a 12-week Memory Boot Camp (MBC) program on cognitive function in older adults with symptoms of Mild Cognitive Impairment.
- Trial name
- NCT04426162
- Testing
- Multi-domain Intervention
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Neurocore
Sleep Disorder, Shift-Work
Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
The purpose of this study is to test the hypothesis that ingestion of the wake-inhibiting drug suvorexant 30 minutes prior to daytime sleep initiation in individuals working overnight shifts will significantly improve both…
- Trial name
- NCT02491788
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Cardiovascular Risk Factor
Program of Physical, Nutritional and Psychological Activities With Overweight Schoolchildren
Obesity has been considered as one of the primary factors for the development of pathologies and cardiovascular risk factors. In the child it has been mediator for the development of these comorbidities still in childhood, in the…
- Trial name
- PANPES (NCT03041142)
- Testing
- Interdisciplinary intervention, Routine
- Volunteers
- 33 people
- Sponsor
- Universidade Federal do vale do São Francisco
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