Clinical trials: Psychological Disorders
Alzheimer Disease, Mild Cognitive Impairment
Evaluating the Efficacy of Artificial Intelligence-based Computer Aided Diagnosis Software That Assists in Determining Whether or Not to Conduct Amyloid PET for the Diagnosis of Alzheimer's Disease by Predicting Amyloid PET Positivity in Mild Cognitive Impairment Patients
Purpose of clinical trial; This clinical trial is designed to evaluate the effectiveness of 'NeuroAI' prediction accuracy compared to the amyloid PET test results by retrospectively collecting medical data of patients with mild…
- Trial name
- NCT05383053
- Testing
- NeuroAI
- Where
- South Korea
- Volunteers
- 227 people
- Sponsor
- Neurozen Inc.
Alcohol Exposed Pregnancy
Reducing Alcohol Exposed Pregnancy Risk: EARLY Randomized Controlled Trial
The EARLY Randomized Controlled Trial (RCT) will test the finalized EARLY preventive intervention against one comparison and one control condition.
- Trial name
- EARLY RCT (NCT01446653)
- Testing
- Motivational Interviewing plus feedback, Video, Informational Brochure
- Where
- 2 sites in United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Binge Eating Disorder, Obesity
Effectiveness of Cognitive Behavioral Therapy Plus Nutritional Counseling in Promoting Weight Loss in People With Binge Eating Disorder
This study will evaluate the effectiveness of adding nutritional counseling to cognitive behavioral therapy in treating obese people with binge eating disorder.
- Conditions
- Binge Eating Disorder, Obesity, Overweight
- Trial name
- NCT00601653
- Testing
- Cognitive behavioral therapy plus general nutrition counseling (CBT+GN), Cognitive behavioral therapy plus low energy density diet counseling (CBT+LED)
- Volunteers
- 50 people
- Sponsor
- Yale University
Psychedelic Experiences, Amnesia
Pilot RECAP Study in Healthy Volunteers
The primary objective of the RECAP Study Program is to investigate the role played by conscious experience in the antidepressant effects of the psychedelic agent psilocybin.
- Trial name
- RECAP (NCT04842045)
- Testing
- Psilocybin and Midazolam
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Type 2, Coronary Artery Disease
Optimizing Audit and Feedback for Primary Care
There remains a large gap between ideal and actual care provided to patients with chronic diseases. Performance feedback reports are often used as a foundation for quality improvement interventions.
- Trial name
- NCT00996645
- Testing
- Worksheet to facilitate goal-setting and action plans
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Adult Day Programs, Continuing Care
Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family/friend Caregivers
This study seeks to understand the effects of adult day programs on older adults, especially those with dementia, and their caregivers.
- Conditions
- Adult Day Programs, Continuing Care, Old Age; Dementia, Family/Friend Caregivers
- Trial name
- NCT06496945
- Testing
- Adult day program use, Other community care (non-attendees)
- Where
- 4 sites in Canada
- Volunteers
- 3,000 people
- Sponsor
- York University
Depressive Symptoms, Anxiety
Psychopharmacology of Psilocybin in Cancer Patients
This research is being done to study the psychological effects of psilocybin in cancer patients. Psilocybin is a naturally occurring substance found in some mushrooms that some cultures have used for centuries in religious…
- Conditions
- Depressive Symptoms, Anxiety, Cancer
- Trial name
- NCT00465595
- Testing
- psilocybin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Eating Disorder, Female Adolescents
Pilates Program in Female Adolescent With Eating Disorders
Physical exercise helps patients with eating disorders by improving their physical fitness, quality of life and other specific variables of this pathology.
- Trial name
- PITCA (NCT03667183)
- Testing
- Pilates
- Volunteers
- 15 people
- Sponsor
- Universidad Pablo de Olavide
LPS, Mood Disorders
Resistance Exercise Plus Vinegar Ingestion on Biomarkers in Healthy Adults
Given its capacity to stimulate exercise-induced neuroplasticity at lower doses compared to aerobic exercise, resistance exercise has become the top-recommended rehabilitation approach for individuals with neurocognitive…
- Conditions
- LPS, Mood Disorders, Cognitive Change
- Trial name
- NCT06437405
- Testing
- Vinegar liquid, vinegar pill
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Major Depressive Disorder, Dysthymic Disorder
Testing a Precision Psychotherapy System for Low-income Patients
The purpose of this study is to evaluate the feasibility of an evidence-based system to recommend core interventions, before the beginning of treatment, to psychotherapists treating low-income patients with depressive or anxiety…
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Specific Phobia, Social Anxiety Disorder
- Trial name
- ML_LMIC (NCT05118594)
- Testing
- Pre-treatment psychotherapy recommendations
- Volunteers
- 111 people
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Anxiety, Depression
An Open Trial of Metacognitive Therapy for Anxiety and Depression in Cancer
Survival rates in cancer continue to improve, with over 2 million adult cancer survivors in the United Kingdom, projected to increase to 4 million by 2030.
- Conditions
- Anxiety, Depression, Cancer
- Trial name
- NCT02580656
- Testing
- Metacognitive Therapy
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Liverpool
Physical Inactivity, Occupational Stress
Braining - Physical Exercise in Psychiatry - Evaluation of Feasibility, Implementation and Health Among Staff
Physical exercise (PE) shows beneficial effects on somatic and psychiatric symptoms. "Braining" is a clinical invention where psychiatric staff exercise together with patients to help patients start and execute PE regularly.
- Trial name
- NCT05111756
- Where
- Sweden
- Volunteers
- 49 people
- Sponsor
- Region Stockholm
Alzheimer Disease
Drug-Drug Interaction to Study the Effect of BMS-708163 on Pharmacokinetics (PK) of Galantamine Extended Release (ER)
The purpose of the study is to find out if the plasma concentration of galantamine extended release is changed when BMS-708163 is administered at the same time.
- Trial name
- NCT01039194
- Testing
- galantamine, BMS-708163
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Bristol-Myers Squibb
Prebiotics, Anxiety
Gut-brain Axis, Brain Function, and Behaviour.
The aim is to test if dietary supplementation with prebiotics reduces measures of anxiety in healthy human participants with high self-reported levels of anxiety.
- Conditions
- Prebiotics, Anxiety, Humans, Magnetic Resonance Imaging
- Trial name
- NCT03554694
- Testing
- Prebiotics
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Bipolar Disorder
Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)
The purpose of this study is to determine if flexibly-dosed ziprasidone is safe and effective for the treatment of children and adolescents (ages 10-17) with bipolar I disorder (manic or mixed).
- Trial name
- NCT00257166
- Testing
- Ziprasidone oral capsules
- Where
- 50 sites in United States
- Volunteers
- 238 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Attention Deficit Disorder With Hyperactivity
An Efficacy and Safety Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the safety and efficacy of Osmotic Release Oral System (OROS) methylphenidate in participants with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01012622
- Testing
- Osmotic Release Oral System (OROS) Methylphenidate Hydrochloride
- Volunteers
- 142 people
- Sponsor
- Janssen Korea, Ltd., Korea
Type 2 Diabetes Mellitus, Mild Cognitive Impairment
LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes
This is an investigator-led prospective, randomized, open label, parallel study to explore and evaluate the therapeutic effects of Liraglutide, Empagliflozin and Linagliptin on the cognitive function in T2DM patients with mild…
- Trial name
- LIGHT-MCI (NCT05313529)
- Testing
- Liraglutide, Empagliflozin, Linagliptin
- Where
- 5 sites in China
- Volunteers
- 396 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Mental Health Disorder, PTSD
Psychosocial and Economic Impacts of Narrative Exposure Therapy for Violence Survivors in Eastern DRC
The objective of the study is to evaluate the impact of Narrative Exposure Therapy (NET) delivered by local counselors, on the mental health and socio-economic empowerment of survivors of Sexual and Gender Based Violence (SGBV)…
- Conditions
- Mental Health Disorder, PTSD, Depression Anxiety Disorder, Gender-based Violence
- Trial name
- NCT04841031
- Testing
- NET Treatment, Alternative Intervention
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 1,053 people
- Sponsor
- World Bank
PTSD
Efficacy of Compassion Focused Therapy in Group for Posttraumatic Stress Disorder
The purpose of this study is to determine the efficacy of a 8-week program of Compassion Focused Therapy in Group comparing to Supportive Cognitive Behavioral Therapy in Group for patients with Posttraumatic Stress Disorder.
- Trial name
- GCFT-PTSD (NCT03154931)
- Testing
- CBT-SG, CFT-G
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo General Hospital
Erectile Dysfunction, Stem Cells
Intracavernous Injection of Autologous Mesenchymal Stem Cells in the Treatment of Erectile Dysfunction Resistant to Oral Treatment in Patients With Type I Diabetes
Diabetes is a major concern in public health because of its high frequency and its negative consequences. Erectile dysfunction (ED) is present, regardless of age, in 50 to 75% of men with diabetes.
- Conditions
- Erectile Dysfunction, Stem Cells, Diabetes Mellitus, Type 1
- Trial name
- MESERIC (NCT03361631)
- Testing
- Autologous Bone Marrow derived Mesenchymal Stem Cells
- Volunteers
- 13 people
- Sponsor
- Central Hospital, Nancy, France
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