Clinical trials: Psychology
Nurse-Patient Relations, Psychology, Social
Meaning-Centered Psychotherapy at Home
The purpose of this study is to train nurses from the VNS Health Visiting Nurse Service to deliver Meaning-Centered Psychotherapy for Palliative Care Patients (MCP-PC) to homebound people, and to evaluate how effective MCP-PC is…
- Trial name
- NCT05495737
- Testing
- Meaning-Centered Psychotherapy/MCP-PC Training, Meaning-Centered Psychotherapy/MCP-PC, Treatment As Usual/TAU
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Stress (Psychology)
Effects of Mechanical Massage on Sleep Quality, Immunity, and Stress
This bicentric, randomized, single-blind clinical investigation aims to evaluate the effects of a multisession mechanical massage (endermologie) program on sleep quality, immune function, and stress levels in individuals…
- Trial name
- NCT07811284
- Testing
- Mechanized Massage (LPG Cellu M6 Alliance)
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bescored
Anxiety, Somatization
Effect of an ACT-based Intervention to Reduce Anxiety in Medical Students
Objective: To evaluate the association between ACT-process with negative psychological variables in a cross-sectional design, and to evaluate the effect of an ACT-based intervention to diminish anxiety in a sample of medical…
- Conditions
- Anxiety, Somatization, Depressive Symptom, Stress (Psychology)
- Trial name
- ACT (NCT07813520)
- Testing
- ACT_based intervention, Active Control group
- Where
- Mexico
- Volunteers
- 135 people
- Sponsor
- University of Guadalajara
Stress (Psychology)
Feasibility of Implementing the Internet-Delivered Stress Recovery Intervention FOREST for Healthcare Staff in a Real-World Healthcare Setting
The aim of the study is to assess the feasibility of implementing the internet-delivered stress recovery intervention FOREST for healthcare staff in a real-world healthcare setting and to obtain preliminary estimates of changes…
- Trial name
- FOREST-IN (NCT07808762)
- Testing
- FOREST
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Kidney Transplant Failure and Rejection
Treatment of Early Borderline Lesions in Low Immunological Risk Kidney Transplant Patients (TRAINING)
Background: Subclinical inflammation, including borderline lesions (BL), is very common (30-40%) after kidney transplantation (KT), even in low immunological risk patients, and can lead to interstitial fibrosis/tubular atrophy…
- Trial name
- NCT04936282
- Testing
- Grafalon, Normal Treatment
- Where
- 4 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Fundación Canaria Instituto de Investigación Sanitaria de Canarias
Emotional Distress, Anxiety
Mindfulness Intervention for Emotional Distress: An EEG Study
This is a randomized controlled trial examining the efficacy and neural mechanisms of a standardized Mindfulness Intervention for Emotional Distress (MIED) in adults with subclinical emotional distress.
- Conditions
- Emotional Distress, Anxiety, Depression, Stress (Psychology)
- Trial name
- MIED-RCT (NCT07692269)
- Testing
- MIED, PMR
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University
Body Dysmorhpic Disorder, Positive Psychology
Effectiveness of a Self-Guided Intervention for Body Dysmorphia and Positive Psychological Outcomes Among Adolescents
The goal of this clinical trial is to learn if self guided intervention for body dysmorphia works to treat the symptoms and effective in bringing positive psychological outcomes in adolescents.
- Trial name
- NCT07803796
- Testing
- Self-Guided Psychological Intervention for Body Dysmorphic Disorder (6 weeks)
- Volunteers
- 100 people
- Sponsor
- National University of Modern Languages
Nurses, Resilience, Psychological
Effectiveness of Positive Psychological Intervention on Resilience Improvement in Nurses
The nursing profession, comprising over 27.9 million individuals and representing 59% of the health sector, plays a critical role in frontline healthcare globally.
- Conditions
- Nurses, Resilience, Psychological, Positive Psychology
- Trial name
- NCT06572202
- Testing
- Positive Psychology Intervention
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fitria Endah Janitra
Rejection; Transplant, Kidney, Rejection; Transplant, Pancreas
A Multicenter Randomized Controlled Trial to Treat Acute T Cell Mediated Rejection in Kidney and Kidney-Pancreas Transplant Recipients
After a kidney or a kidney-pancreas transplant, some patients may face problems with their new organs. This happens because the body sometimes makes a mistake and tries to get rid of the organ. This problem is called rejection.
- Trial name
- TACKLE-IT (NCT06474273)
- Testing
- Methylprednisolone, Prednisone
- Where
- 30 sites in Australia, Canada and 1 more
- Volunteers
- 540 people
- Sponsor
- University of Sydney
No Disease or Condition is Being Studied, Stress (Psychology)
Caring for Dementia Caregivers in Ethnic Immigrant Communities
Many caregivers of people with Alzheimer's disease or other dementias-especially those in immigrant communities who don't speak English well-don't get access to helpful, proven support programs.
- Trial name
- NCT07550075
- Testing
- K-Savvy, Healthy Living
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Heart Transplant, Pediatric Heart Transplant
Non-invasive Prediction of EArly Cardiac rEjection
Acute rejection remains a major cause of morbidity and mortality in pediatric patients after heart transplant. In order to screen for rejection, most centers perform heart catheterizations with endomyocardial biopsies frequently…
- Conditions
- Heart Transplant, Pediatric Heart Transplant, Rejection, Cardiac MRI
- Trial name
- PEACE (NCT07770659)
- Where
- 22 sites in United States
- Volunteers
- 200 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Transplant, Kidney Transplant Failure and Rejection
(TNX-1500) in Kidney Transplant Recipients
The primary objective is to investigate the safety of TNX-1500, an FC-modified anti-CD154 mAb, in five kidney transplant recipients at 12 months.
- Conditions
- Kidney Transplant, Kidney Transplant Failure and Rejection, Immunosuppression, Immunosuppression After Kidney Transplantation
- Trial name
- TONIX-1500 (NCT07204080)
- Testing
- TNX-1500, Kidney Transplant
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Ayman Al Jurdi, MD
Stress (Psychology)
Effectiveness of A Mindfulness-centered Stress Management AI Chatbot to Reduce Stress and Enhance Mental Health Among Men Who Have Sex With Men in China
The goal of this randomized controlled trial is to evaluate the effectiveness of a mindfulness-centered stress management AI chatbot in reducing perceived stress and enhancing mental health among Chinese men who have sex with men…
- Trial name
- MSM (NCT07732621)
- Testing
- Mindfulness-centered stress management AI chatbot, Psychoeducation
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Transplant
Immune Function as Predictor of Infectious Complications and Clinical Outcome in Patients Undergoing Solid Organ Transplantation
At Rigshospitalet, Denmark, we will examine the immune function of solid organ transplant recipients before and at several timepoints after transplantation as well as the clinical outcome, especially the risk of infections…
- Trial name
- Immune-Mo (NCT03847285)
- Testing
- solid organ transplantation
- Where
- Denmark
- Volunteers
- 188 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anxiety, Stress (Psychology)
Cellphone Access for Lowered Maternal Anxiety and Stress in Cesarean Sections
This study looks at whether allowing mothers to use their personal cellphone during a planned cesarean section (C-section) under spinal anesthesia can reduce stress and anxiety and improve their overall birth experience.
- Trial name
- CALMAS-CS (NCT07759726)
- Testing
- Cell Phone Use
- Where
- Lebanon
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Solid Organ Transplantation, Bone Marrow Transplantation
Biomarkers in Transplant Recipients to Improve Outcomes
The objective of this study is to evaluate whether certain proteins, expressed in biological tissues can indict a better understanding of the effect of drugs that are used to treat rejection, and of processes leading to rejection…
- Trial name
- NCT01163578
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Pittsburgh
Kidney Transplant, Rejection
Detection of Circulating Kidney DNA in Kidney Transplant Patients Facing an Episode of Graft Rejection
In France, 3,500 kidney transplants are carried out per year; and 40,000 people succeed in 2019 with a kidney transplant. Despite regular medical monitoring, nearly 30% of transplant patients will develop rejection.
- Trial name
- DART-RREGREF (NCT06351488)
- Where
- 3 sites in France
- Volunteers
- 319 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Transplant Failure and Rejection, Kidney Transplant; Complications
ECP-DL Cell Infusion for Induction in Living Donor Kidney (LDK) Transplants
This is a phase 1 trial, 36 month duration for subjects with end-stage renal disease (ESRD). The objectives of the trail are1) Determine the safety of ECP-DL cell infusion in living donor renal transplant recipients.
- Trial name
- ECP (NCT07083830)
- Testing
- ECP-DL treated mononuclear cell infusion
- Volunteers
- 24 people
- Sponsor
- Northwestern University
Intimate Partner Violence (IPV), Climate Change
Smartphone Climate Adaptation and IPV Intervention for Women in Informal Settlements in Kenya
This study is testing a smartphone-delivered program to help women living in informal settlements in Kenya manage intimate partner violence (IPV) and stress related to extreme weather events.
- Conditions
- Intimate Partner Violence (IPV), Climate Change, Stress (Psychology)
- Trial name
- NCT07492368
- Testing
- Event-Triggered WINGS-Based EMI, Single-Session Mobile WINGS
- Where
- Kenya
- Volunteers
- 272 people
- Sponsor
- Africa Institute of Mental and Brain Health (AFRIMEB)
Heart Transplant Failure and Rejection
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant
Immunosuppressive therapy is required to prevent organ rejection, however, dosing of immunosuppressive agents is complicated by patient-specific differences impacting the body's absorption and elimination of these agents.
- Trial name
- NCT04380311
- Testing
- Tacrolimus Dosing Support Tool
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Utah