Clinical trials: Psychosocial Impairment
Mental Health Impairment, Mental Health Disorder
Youth FORWARD Phase 2 YRI and EPP Study
Objectives: The objectives of this research proposal are to study the delivery of an evidence-based mental health intervention in the alternate setting of youth employment programs tied to regional economic development and to…
- Conditions
- Mental Health Impairment, Mental Health Disorder, Psychosocial Problem
- Trial name
- NCT03542500
- Testing
- Youth Readiness Intervention (YRI), Entrepreneurship Training
- Where
- 3 sites in Sierra Leone
- Volunteers
- 1,783 people, healthy volunteers welcome
- Sponsor
- Boston College
Schizophrenia, Schizoaffective Disorder
The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
The study aimed to investigate whether transcranial direct current stimulation could modify auditory hallucination, insight, neurocognitive function, heart rate variability, psychosocial functioning and quality of life in…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucination, Verbal, Neurocognitive Dysfunction
- Trial name
- NCT03388554
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Neuromuscular Diseases, Cerebral Palsy
Effects of Power Wheelchair Soccer for Individuals Presenting With Physical Impairments
This study is a prospective interventional study. It will be conducted at a single center with participants who have neuromotor impairments.
- Trial name
- chair-soccer (NCT06259643)
- Testing
- Power wheelchair soccer
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Catholique de Louvain
Mild Cognitive Impairment
Support Groups for Patients With Mild Cognitive Impairment and Their Partners
This study aims at developing and evaluating a support group program for patients with mild cognitive impairment (MCI) and their partners. These patients have defective memory function but are not demented.
- Trial name
- NCT00285753
- Testing
- support groups
- Where
- 2 sites in Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Mild Cognitive Impairment
Evaluation of an Intervention for Living With Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a significant risk factor for dementia. Persons with MCI experience cognitive changes, most typically affecting memory; that are greater than those experienced in "normal" aging.
- Trial name
- NCT02083237
- Testing
- Behavioural Intervention Program
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Baycrest
PTSD, Functioning, Psychosocial
What Difficulties Do Children and Adolescents Experience in Everyday Activities After a Traumatic Event? Focus Groups and Delphi Survey for the Development of a Questionnaire on PTSD-related Functional Impairment
Post-traumatic Stress Disorder (PTSD) in children and adolescents is often associated with a myriad of significant impairments in daily functioning, including family relationships, school/work, leisure time activities, and social…
- Trial name
- NCT05984706
- Testing
- Focus groups and Delphi Questionnaire
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Children's Hospital, Zurich
Schizophrenia, Schizoaffective Disorder
Theta tACS During Working Memory Training: A Pilot Study of the Effects on Negative Symptoms of Schizophrenia
In this randomized double-blind trial, we investigated whether externally induced left-hemispheric frontoparietal theta synchronization by multi-electrode online theta (6Hz) transcranial alternating current stimulation (tACS)…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Negative Symptoms, Working Memory Training
- Trial name
- NCT04545294
- Testing
- Theta tACS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Breast Cancer
Study of the Effects of Chemotherapy on Memory and Other Mental Functions in Women With Breast Cancer
Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog.
- Trial name
- NCT00260975
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Mild Cognitive Impairment, So Stated
Feasibility Study of a Computerized Cognitive Stimulation
This non-pharmacological interventional feasibility study evaluate a computerized cognitive stimulation program in elderly with mild cognitive impairment.
- Trial name
- PSCogStim (NCT03195829)
- Testing
- Computerized Cognitive Stimulation, Multimedia-based internet
- Volunteers
- 20 people
- Sponsor
- Leila DJABELKHIR
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Stroke Prevention, Blood Pressure
Stroke Telemedicine Outpatient Prevention Program for Blood Pressure Reduction
The purpose of this pilot trial is to compare post-stroke care blood pressure (BP) treatment using an interdisciplinary telehealth model [called the Stroke Telemedicine Outpatient Program (STOP) for Blood Pressure Reduction] to…
- Conditions
- Stroke Prevention, Blood Pressure, Telemedicine, Psychosocial Impairment
- Trial name
- STOP-Stroke (NCT03923790)
- Testing
- Educational Packet, Phone call at 72 hours by discharge nurse navigator, Telehealth visit at 7 days, 1 month, 3 months, and 5 months after discharge
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetes type1
Current State of Impaired Awareness of Hypoglycaemia in People With Type 1 Diabetes
Rationale: Hypoglycaemia is the most frequent complication of insulin treatment in individuals with type 1 diabetes and a limiting factor for achieving optimal glycaemic control.
- Trial name
- NCT04311021
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 700 people
- Sponsor
- Radboud University Medical Center
Mental Health Impairment, Peer Group
Paths to Everyday Life (PEER) - a Community-based Peer Support Intervention
The aim of this randomized, two-arm, investigator initiated, multi municipal, parallel-group superiority trial is to compare the effect on self-reported personal recovery of the following interventions: (1) 10-week group-based…
- Conditions
- Mental Health Impairment, Peer Group, Mental Health Disorder, Problems Psychosocial
- Trial name
- PEER (NCT04639167)
- Testing
- Paths to everyday life (PEER)
- Where
- Denmark
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Temporomandibular Disorder, Temporomandibular Joint Dysfunction
Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders
Temporomandibular disorder is a multifactorial condition that involves the temporomandibular joint, masticatory muscles, and surrounding structures and is influenced by biological, psychological, and social factors.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Dysfunction, Trauma Exposure, Childhood Traumas
- Trial name
- NCT07292103
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Bipolar Disorder
Functional Remediation for Bipolar Disorder
Bipolar Disorder is a major mood disorder with periodic mood episodes that may be very distressing, both to the individual and to others.
- Trial name
- NCT03403179
- Testing
- Functional Remediation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Mental Health, Depression
rTMS for Emotional Difficulties in Verterans
Mental illness rarely occurs as a single, easily categorized condition. Instead, multiple disorders often co-occur. This complicates the treatment plan for many Veterans, especially those suffering the most severe dysfunction.
- Conditions
- Mental Health, Depression, rTMS, Anxiety
- Trial name
- rTMS (NCT03749967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
Obesity, Impaired Health
Effectiveness of a Smartphone App for Adolescent Obesity Management
Though face-to-face treatment of childhood obesity can be effective, it is time consuming and costly. This study will test whether treatment can be delivered via an Android app and whether such treatment reduces obesity.
- Conditions
- Obesity, Impaired Health, Psychosocial Problem, Physical Activity
- Trial name
- NCT01804855
- Testing
- W82GO, smartphone application
- Where
- 2 sites in Ireland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Children's University Hospital, Ireland
Stress, Psychological, Mental Health Impairment
A Psychosocial Program Impact Evaluation in Jordan
The study aims to deliver a robust pre-post evaluation of the wellbeing impacts of an innovative, brief, and scalable psychosocial intervention, delivered to refugee youth living in urban settlements in Jordan.
- Trial name
- NCT03012451
- Testing
- Advancing Adolescents
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Yale University
Emotional Distress, Functional Impairment
Evaluation of Three School-based Mental Health Preventive Interventions in France
To meet adolescents' needs regarding mental health vulnerability, this study aims to propose and evaluate three original school-based preventive interventions delivered to French 13y-adolescents, with respect to their effects on…
- Conditions
- Emotional Distress, Functional Impairment, Psychosocial Problem, Wellbeing
- Trial name
- NCT06059092
- Testing
- Adapt Module, Engage Module, Interact Module
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Nimes