Clinical trials: Puerperal Disorder
Caesarean Section, Mother-Child Relations
Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL
The purpose of this study is to assess the safety and efficacy of the mother's active pushing during cesarean delivery.
- Conditions
- Caesarean Section, Mother-Child Relations, Post Operative Pain, Postpartum Depression
- Trial name
- NCT05520580
- Testing
- Mother's push during CS
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Postpartum Hemorrhage
Prevention of Postpartum Hemorrhage With TXA
Hemorrhage remains the leading cause of maternal death worldwide. Tranexamic acid has been shown to reduce rates of hemorrhage when given prophylactically prior to cesarean delivery.
- Trial name
- TXA (NCT03326596)
- Testing
- Tranexamic Acid 1000 mg/10ml normal saline infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Postpartum Hemorrhage
The Association Between Shock Index and Severity of Postpartum Blood Loss
The present study aims to determine the relationship between postpartum changes in the shock index and the severity of blood loss and other PPH results.
- Trial name
- NCT03135158
- Testing
- Exposure to vaginal delivery
- Where
- Colombia
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Period
Effect of Baby Massage on Postnatal Maternal Attachment and Depression
This study aims to examine the effects of providing infant massage training to mothers in the early postpartum period with the goal of preventing postpartum depression and enhancing maternal bonding.
- Trial name
- NCT06475885
- Testing
- Infant Massage Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gazi University
Depression, Postpartum
Determining the Effect of Telephone Counseling Service Provided to Primiparous Mothers on Postpartum Depression
The aim of this study is to determine the effect of telephone counseling services provided to primiparous mothers on postpartum depression.
- Trial name
- NCT06070168
- Testing
- Telephone Counseling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Analgesia, Obstetrical, Postpartum Hemorrhage
Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery
In this randomized, double-blind control trial to evaluate the effect of ketorolac given at the time of cord clamp has on estimated blood loss and postcesarean pain control.
- Conditions
- Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT02509312
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Postpartum Hemorrhage
Umbilical Cord Drainage to Prevent Postpartum Hemorrhage
This study aims to analyze whether there is a significant difference in the occurrence of postpartum hemorrhage between women who underwent umbilical cord drainage and those who did not.
- Trial name
- CORD-PPH (NCT07401160)
- Testing
- Umbilical Cord Drainage, Standard Active Management of Third Stage (No Cord Drainage)
- Where
- 2 sites in Honduras
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Postpartum Depression (PPD), Pregnancy
Clinical Validation of a Predictive Test for Postpartum Depression
The goal of this observational study is to develop a blood test that may be predictive of postpartum depression. This Blood test is investigational and not yet FDA approved.
- Trial name
- PREVAIL (NCT06831968)
- Testing
- Enlighten
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Depression, Postpartum
Multimodal Biomarkers and Precision TMS for Postpartum Depression
The purpose of this study is to identify multimodal biological markers associated with postpartum depression (PPD) and to evaluate the effectiveness of precision brain stimulation treatment.
- Trial name
- MOTHER-TMS (NCT07757815)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 2 sites in Macau
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Macau
Midwifery Student
The Effect of Gamification-Based Instructional Design Developed
Turkish) Abstract: Purpose: Considering the importance of postpartum hemorrhage management in reducing preventable maternal deaths and the key role midwives play in providing this care, it is important to increase the knowledge…
- Trial name
- PPH-GamEd (NCT07207590)
- Testing
- web-based gamification application, control group: traditional classroom learning techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Puerperal Infection
Effect of Vaginal Douching With Betadine Before CS for Prevention of Post Operative Infections
The present study was a prospective randomized controlled trial in which subjects received a vaginal preparation with povidone-iodine solution immediately prior to caesarean delivery or received no vaginal preparation
- Trial name
- NCT03397615
- Testing
- Betadine douches
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Cairo University
To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT
Research Objective: Primary outcome -To compare efficacy Intrauterine vs Sublingual MISOPROSTOL in addition to Oxytocin in reducing blood loss of post-cesarean section in high risk women Secondary outcome -To study…
- Trial name
- NCT04560218
- Testing
- sublingual Misoprostol, Intrauterine Misoprostol
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Obesity, Pregnancy
Promoting Health in Pregnancy and Postpartum
The purpose of this study is to examine the impact of a lifestyle intervention on gestational weight gain, postpartum weight loss, and other secondary outcomes relative to a usual care control group.
- Conditions
- Obesity, Pregnancy, Overweight
- Trial name
- HIPP (NCT02260518)
- Testing
- Lifestyle Intervention, Standard Care
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Pain, Postpartum Depression
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
The purpose of this study is to identify pharmacokinetics of postpartum ketamine infusion. This study will assess ketamine kinetics and metabolism in this setting.
- Trial name
- PREPARE-2 (NCT06767566)
- Testing
- Ketamine (Ketalar)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Preeclampsia Postpartum, Adverse Pregnancy Outcomes
A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
United States maternal mortality and preterm birth rates are among the highest among high-income countries due in part to a combination of racial, regional and socioeconomic disparities in access to care and overall health.
- Trial name
- AW2H (NCT06353256)
- Testing
- usual postpartum care, usual postpartum care + community health worker intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Prevention of Post Partum Haemorrhage
A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section
This is a randomized trial comparing oxytocin versus oxytocin + syntometrine in the prevention of post partum haemorrhage in patients undergoing caesarean section
- Trial name
- NCT02046499
- Testing
- Oxytocin, Oxytocin ergometrine
- Where
- South Africa
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- University of Pretoria
Postpartum Hemorrhage
Tranexamic Acid Pharmacokinetics During Postpartum Hemorrhage
Postpartum hemorrhage (PPH) accounts for 20-25 percent of maternal deaths worldwide. Tranexamic Acid (TXA) is an antifibrinolytic agent that has been shown to reduce the estimated blood loss after delivery and is recommended by…
- Trial name
- NCT03863964
- Testing
- blood test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy, Weight Gain
Cardiovascular Health in Postpartum Women Diagnosed With Excessive Gestational Weight Gain
The investigators will test the efficacy of a tailored behavioral lifestyle modification program to support cardiovascular health in postpartum women with excessive gestational weight gain.
- Trial name
- NCT02142452
- Testing
- behavioral intervention, Usual Prenatal Care
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stanford University
Postpartum Depression, Mother-Infant Interaction
Mobile-Based Exercise in Postpartum Period
Postpartum depression is a global mental health problem affecting 13 million women worldwide each year. It is defined as minor or major depression that occurs up to one year after birth and is estimated to affect 5 to 25% of…
- Trial name
- NCT06390540
- Testing
- Exercise
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara University
Postpartum Hemorrhage, Postpartum Preeclampsia
Postpartum Video Education
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression
- Trial name
- NCT05159726
- Testing
- Video Education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University