Clinical trials: Pulmonary Atelectases
Obesity, Respiratory Insufficiency
Open Lung Strategy in Critically Ill Morbid Obese Patients
The goal of this interventional crossover study in morbidly obese intubated and mechanically ventilated patients is to describe the respiratory mechanics and the heart-lung interaction at titrated positive end-expiratory pressure…
- Conditions
- Obesity, Respiratory Insufficiency, Right-Sided Heart Failure, Pulmonary Atelectasis
- Trial name
- NCT02503241
- Testing
- PEEP INCREMENTAL, PEEP DECREMENTAL
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Massachusetts General Hospital
Respiratory Distress Syndrome (Neonatal)
Open-label Randomized Controlled Trial of Two Protocols for Weaning From High Frequency Oscillatory Ventilation in Preterm Neonates With Respiratory Distress Syndrome Admitted in the NICU of Mansoura University Children Hospital
Our study is a randomized controlled trial that compares two weaning protocols of preterm infants with respiratory distress syndrome who are ventilated on high frequency oscillatory ventilation in order to establish the best…
- Trial name
- NCT07202299
- Testing
- HFOV weaning protocol 1, HFOV weaning protocol 2
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University Children Hospital
Postoperative Pulmonary Complications
Consensus Statements on Definition, Components and Grading of Postoperative Pulmonary Complications
An international team of experts is working on a project called PrECiSIOn to develop a clear, consistent definition of PPCs. The goals of this study are to: Define postoperative pulmonary complications in a way that makes sense…
- Trial name
- PrECiSIOn (NCT06916598)
- Testing
- Delphi study, Structured Interview
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Postoperative Complications
Air-test as a Predictor of Pulmonary and Systemic Complications After Laparoscopic Surgery
One of the main risk factors for the development of postoperative pulmonary complications (PPC) in postsurgical patients is the persistence of atelectasis during this period.
- Trial name
- NCT04895527
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Atelectasis, Postoperative Pulmonary
Driving Pressure-guided PEEP Titration in Robot-assisted Laparoscopic Surgeries
The purpose of this study is to investigate the effect of driving-pressure guided positive end-expiratory pressure (PEEP) titration.
- Trial name
- NCT04327193
- Testing
- Titrated PEEP based on driving pressure, Conventional PEEP
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Neonatal Respiratory Distress
In-person Versus Online Debriefing in HBB
The objective of this study is to assess the effectiveness of online formative feedback and debriefing on nursing and medical students enrolled in the HBB course in comparison to traditional face-to-face feedback.
- Trial name
- NCT05257499
- Testing
- On line debriefing
- Where
- 2 sites in Lebanon
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Infant, Premature, Neonatal Respiratory Distress
Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants
Oxygen treatment is common in management of preterm babies requiring intensive care. Delivery of too much or too little oxygen increase the risk of damage to eyes and lungs, and contributes to death and disability.
- Conditions
- Infant, Premature, Neonatal Respiratory Distress, Oxygen Saturation, Bronchopulmonary Dysplasia
- Trial name
- MODERATION Neo (NCT05030012)
- Testing
- Automated Control, Manual Control
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Vapotherm, Inc.
Postoperative Atelectasis, Lung Recruitment
Lung Recruitment Maneuvers for Postoperative Atelectasis Prevention After Idiopathic Adolescents' Scoliosis Correction
The investigators hypothesized that an ultrasound-guided lung recruitment maneuvers would be more effective in preventing postoperative atelectasis than conventional alveolar recruitment after surgical correction of idiopathic…
- Conditions
- Postoperative Atelectasis, Lung Recruitment, Scoliosis; Adolescence
- Trial name
- NCT05325463
- Testing
- conventional lung recruitment, ultrasound- guided lung recruitment
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Pediatric Respiratory Diseases, Bronchiolitis
Assessment of NeuroBOX and NeuroPAP in Infants.
Non-invasive ventilation (NIV, delivered via a mask or cannulas) permits to reduce the need for tracheal intubation in infants who needs a ventilatory support.
- Conditions
- Pediatric Respiratory Diseases, Bronchiolitis, Infant Respiratory Distress Syndrome
- Trial name
- NeuroPap2 (NCT03650478)
- Testing
- NeuroPAP ventilation (2h) and NeuroBox monitoring (23h), NeuroPAP ventilation (4h) and NeuroBox monitoring (25h)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- St. Justine's Hospital
Neonatal Respiratory Distress
A Study to Evaluate the Use of the Neotech RAM Nasal Cannula for CPAP and Bi-PAP Application in Infants 28-42 Weeks Gestation in a Neonatal Intensive Care Unit (NICU)
This study will explore the RAM Nasal Cannula as a means of providing CPAP and Bi-PAP to infants 28-42 weeks gestation to prevent nasal septal erosion.
- Trial name
- NCT04096235
- Testing
- RAM Nasal Cannula
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Englewood Hospital and Medical Center
Pulmonary, Lung
A Randomized Trial Comparing a Ventilatory Strategy To Prevent Atelectasis Versus a Lateral Decubitus Strategy During Robotic Bronchoscopy (VESPA vs. LADS Trial)
To learn if LADS is better than VESPA at preventing atelectasis during a robotic bronchoscopy.
- Trial name
- NCT05714033
- Testing
- Ventilatory Strategy To Prevent Atelectasis, Lateral Decubitus Strategy (LADS)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- M.D. Anderson Cancer Center
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Atelectasis
Effects of Small-dose S-ketamine on Anesthesia-induced Atelectasis in Anesthetized Patients Accessed by Pulmonary Ultrasound
Background: Atelectasis occurs in the majority of patients with general anesthesia, which can lead to postoperative pulmonary complications (PPCs) and affect the postoperative outcome.
- Trial name
- NCT04745286
- Testing
- S-ketamine, normal saline group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Robotic Surgery, Urologic Surgical Procedures
Timing of Recruitment Maneuver in Robotic Prostate Surgery
Robotic prostate surgery is commonly performed under general anesthesia with carbon dioxide pneumoperitoneum and steep Trendelenburg positioning.
- Conditions
- Robotic Surgery, Urologic Surgical Procedures, Postoperative Pulmonary Complications (PPCs), Pulmonary Atelectasis
- Trial name
- ROBPROREC1 (NCT07662642)
- Testing
- Recruitment maneuver after insufflation and Trendelenburg positioning, Recruitment maneuver in the supine position
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ankara University
Atelectasis
The Effect of Lung Recruitment Maneuver on Postoperative Atelectasis in Children
The investigators compare the degree of atelectasis in recovery room between conventional recruitment maneuver and ultrasonography-guided lung recruitment during surgery.
- Trial name
- NCT03453762
- Testing
- recruitment maneuver, ultrasonography-guided recruitment maneuver
- Where
- South Korea
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Premature Birth, Respiratory Distress Syndrome
Comparison of the Results of Transcutaneous Carbon Dioxide and Oxygen Pressure in Premature Neonates Who Underwent MIST Under HHHFNC or Nasal CPAP Methods
Intratracheal surfactant treatment is applied in Respiratory Distress Syndrome (RDS) Continious Positive Airway Pressure(CPAP) treatment.
- Conditions
- Premature Birth, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- TCOPHC (NCT04505176)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Postoperative Pneumonia, Postoperative Pulmonary Atelectasis
Intravenous Lidocaine Infusion Reduce Postoperative Pulmonary Complications in Patients Undergoing Minimally Invasive Esophagectomy
The goal of this double-center, double-blind, randomized controlled clinical trial is to compare the effect of intravenous lidocaine infusion on postoperative pulmonary complications in patients undergoing minimally invasive…
- Conditions
- Postoperative Pneumonia, Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Edema
- Trial name
- NCT06138041
- Testing
- intravenous lidocaine infusion, Saline
- Volunteers
- 770 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Atelectasis, Ventilation, Mechanical
Impact of Nebulized Dornase Alpha on Mechanically Ventilated Patients
The investigators hypothesized that dornase alpha, administered twice a day (BID) by in-line nebulizer, would improve oxygenation, compliance, and time to extubation in adult patients receiving mechanical ventilation.
- Trial name
- NCT01095276
- Testing
- Pulmozyme (nebulized dornase alpha), Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
COVID-19, Virus; Pneumonia
PEEP Incremental and Decremental Alveolar Recruitment of Critically Ill Corona Virus Disease-19 (COVID-19) Patients
COVID-19 originated from Severe Acut Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection leads to critical condition due to hypoxemic respiratory failure with the background of viral pneumonia.
- Conditions
- COVID-19, Virus; Pneumonia, Atelectasis
- Trial name
- NCT04360837
- Testing
- alveolar recruitment
- Where
- Hungary
- Volunteers
- 2 people
- Sponsor
- Szeged University
Atelectasis
Chest Compression Technique in Infants
Evaluate the effect of chest manual compression technique (CCT) in the variables of oxygenation, hemodynamic and respiratory work in infants with respiratory diseases that are associated with atelectasis.
- Trial name
- NCT01858844
- Testing
- CHEST COMPRESSION TECHNIQUE (CCT)
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes