Clinical trials: Pulmonary Atelectases
Bronchopulmonary Disease
Preterm Lung Patient Registry
The goal of the Preterm Lung Patient Registry is to collect data on individuals with neonatal lung disease to better understand the illness and ultimately improve their care and survival.
- Trial name
- NCT00951366
- Testing
- Patient Registry
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Boston Children's Hospital
Atelectasis
Can 10 Seconds Inspiratory Hold Open Atelectasis in Mechanically Ventilated Patients?
This study evaluates whether sustaining inspiratory pressure for 10 seconds at a time can open collapsed lung areas in non-dependant regions of the lung in mechanically ventilated patients.
- Trial name
- NCT02285894
- Testing
- Inspiratory hold
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Oslo University Hospital
Pleural Effusion, Malignant, Pleural Mesothelioma
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including…
- Conditions
- Pleural Effusion, Malignant, Pleural Mesothelioma, Pleural Empyema, Pulmonary Diseases or Conditions
- Trial name
- VATS (NCT05077111)
- Testing
- Thoracic Epidural Anesthesia, General Anesthesia with One Lung Ventilation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Reda Ashour
Neonatal Respiratory Distress
Vaginal Misoprostol to Improve the Neonatal Respiratory Outcome
Project summary: Objective: To test the hypothesis that administration of vaginal Misoprostol before elective cesarean section will improve the neonatal respiratory outcomes in late preterm and early term neonates through…
- Trial name
- NCT03239327
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 292 people
- Sponsor
- Assiut University
Pulmonary Atelectases, Lung Injury
The Effect of Using High-flow Nasal Oxygen-delivery System in Patients Under Intravenous General Anesthesia
In general anesthesia, gas exchange was altered by shunt and uneven ventilation perfusion ratios. Lung atelectasis was a cause of impaired oxygenation.
- Conditions
- Pulmonary Atelectases, Lung Injury, General Anesthesia
- Trial name
- NCT03019354
- Testing
- high-flow nasal oxygen, Oxygen mask
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Postoperative Pulmonary Atelectases
Lung Ultrasound for the Detection of Pulmonary Atelectasis in the Perioperative Period
Atelectases (collapsed lung areas) of 15-20% of total lung occur in up to 90% of patients who are anaesthetized and intubated. The goal of the present prospective study is to detect atelectatic areas in the perioperative period…
- Trial name
- NCT02121275
- Testing
- Ultrasound of the lungs, Electric impedance tomography
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Transient Tachypnea of the Newborn, Neonatal Respiratory Distress
Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section
Neonatal respiratory morbidities represent a common group of post natal complications including respiratory distress syndrome, transient tachypnea of newborn, and persistent pulmonary hypertension of newborn.
- Trial name
- NCT04780412
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity, Anaesthesia
CPAP/PSV Preoxygenation in Obese Patients
The purpose of this study is to determine whether continuouse positive airway pressure (CPAP), during induction of anaesthesia in morbidly obese patients, result in higher levels of oxygen in the blood.
- Trial name
- NCT01780571
- Testing
- CPAP 5 cm H2O + PSV 5 cm H2O
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Neonatal Respiratory Distress, Oxygenation
Neonatal Oximeter Bias Study
The study aims to determine if there is a systematic difference (bias) between pulse oximeters used in control systems for automated oxygen delivery (A-FiO2) and those used in monitoring systems.
- Trial name
- NOB (NCT06817850)
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Czech Technical University in Prague
Atelectasis, Cesarean Section
Atelectasis by Lung Ultrasonography in Cesarean Sections
In this study aimed to demonstrate that atelectasis developing in the perioperative period of patients undergoing elective cesarean surgery with spinal or general anesthesia methods using lung ultrasound.
- Trial name
- NCT04591327
- Testing
- The Effect of General Anesthesia and Spinal Anesthesia on Postoperative Atelectasis by Lung Ultrasonography in Cesarean Sections
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Lung Collapse
OLA to Lowest DP in Cardiac Surgery
This study aims to compared the effects in driving pressure of an open-lung strategy with a positive end-expiratory pressure (PEEP) titrated to best driving pressure (DP) after a RM versus the recommended protective PEEP of 5…
- Trial name
- NCT03133754
- Testing
- DP-PEEP, RM-5
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Mechanical Ventilation Complication, Postoperative Pulmonary Atelectasis
Flow Controlled Ventilation in Robot-assisted Laparoscopic Surgery
The optimization of ventilation is especially important during general anaesthesia, when active, physiologic respiration suspends and is replaced by non-physiologic mechanical positive pressure ventilation.
- Trial name
- FCV-IMPALA (NCT06256900)
- Testing
- Flow-controlled ventilation, Pressure-controlled ventilation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Pulmonary Atelectasis
Lung Ultrasonography After Laparoscopic Gynecologic Surgery
This study evaluates the influence of surgical and anesthesia-related variable on atelectasis formation during laparoscopic gynecologic oncologic surgery by lung ultrasound.
- Trial name
- LUS-LPS (NCT04116567)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- SONNINO CHIARA
Respiratory Distress Syndrome in Premature Infant, Surfactant Deficiency Syndrome Neonatal
Feasibility Study - Neofact
For therapy of respiratory distress syndrome (RDS) in premature babies, there are several established options. An important therapeutic aspect is the tracheal administration of exogenous surfactant into the child's lung.
- Trial name
- NCT04086095
- Testing
- Neofact application aid
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Lung Ultrasound, Atelectasis
Surgical Positions and Postoperative Atelectasis: A Lung Ultrasound Study
The aim of this study is to prospectively evaluate the effect of surgical position on the development of postoperative atelectasis in patients undergoing surgery in supine, prone, lateral decubitus, and lithotomy positions using…
- Trial name
- NCT07654153
- Testing
- lung ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Cholelithiasis, Epigastric Hernia
Using Pre-op Incentive Spirometer Reduces Chances of Basal Atelectasis in Patients Undergoing Upper Abdominal Surgeries
ABSTRACT Objective: To compare frequency of basal atelectasis in patients undergoing upper abdominal surgery who are provided pre-operative incentive spirometry versus those not provided pre-operative incentive spirometry
- Conditions
- Cholelithiasis, Epigastric Hernia, Duodenal Perforation
- Trial name
- NCT06115941
- Testing
- Pre-Op Incentive Spirometer
- Where
- Pakistan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Dr. Muhammad Naeem
Pulmonary Atelectasis
Ultrasound-guided Alveolar Recruitment in Laparoscopic Gynecological Surgery
The study aims to compare the degree of atelectasis between ultrasound-guided alveolar recruitment group and conventional alveolar recruitment group in patients receiving laparoscopic gynecologic surgery
- Trial name
- NCT03607240
- Testing
- lung ultrasound-guided alveolar recruitment, conventional alveolar recruitment
- Where
- 2 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Respiratory Insufficiency in Children, Newborn Rds
Diaphragmatic Work During HFNC and CPAP Support
The goal of this randomised controlled, cross-over clinical trial is to compare High Flow Nasal Cannulas (HFNC) and Continuous Positive Airways Pressure (CPAP) in neonates over 34 weeks' amenorrhoea (SA) up to children weighing…
- Conditions
- Respiratory Insufficiency in Children, Newborn Rds, Nasal Cannula, CPAP Ventilation
- Trial name
- DiaWorkHFNC (NCT06249009)
- Testing
- Non invasive ventilation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atelectasis
Minimizing Lung Injury During Laparoscopy in Steep Trendelenburg Position
The investigators hypothesize that the level of PEEP is often suboptimally applied in certain operative conditions, such as in laparoscopy with head down (Trendelenburg) positioning.
- Trial name
- optiPEEP (NCT04900714)
- Testing
- Decremental PEEP, Lung ultrasound score, Blood gas analysis
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Respiratory Distress of Newborn, Preterm Birth
Antenatal Dexamethasone for Late Preterm Deliveries
The goal of this clinical trial is to compare dexamethasone in late preterm deliveries. The main questions it aims to answer are: Does antenatal dexamethasone reduce the need for respiratory support in late preterm infants? Does…
- Trial name
- NCT05841121
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 294 people
- Sponsor
- Chulalongkorn University