Clinical trials: Pulmonary Consolidation
Healthy Subjects
Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Younger, Healthy Subjects
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent…
- Trial name
- NCT01832740
- Testing
- brain stimulation
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Elderly Subjects
Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Elderly Healthy Subjects
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent…
- Trial name
- NCT01791790
- Testing
- Stimulation
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Language Development Disorders
Perceptual Learning and Memory Consolidation in Adults With and Without LI
This study tests a memory-based account of atypical speech perception in adults with language-based learning disability (also known as developmental language impairment [LI]).
- Trial name
- NCT03609502
- Testing
- behavioral training
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Intrusive Memories
The Effect of Dronabinol on the Acquisition and Consolidation of Trauma-Associated Memories
The aim of the current project is to investigate the impact of an activation of the cannabinoid system with an exogenous cannabinoid dronabinol (delta-9-tetrahydrocannabinol) on the formation of intrusive memories after analog…
- Trial name
- NCT04871269
- Testing
- Dronabinol
- Where
- Germany
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Lymphoid Leukemia in Remission, Stage I Chronic Lymphocytic Leukemia
Tositumomab and Iodine I 131 Tositumomab in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma in First Remission
This phase II trial studies how well tositumomab and iodine I 131 tositumomab works in treating patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that have had their first decrease in or…
- Conditions
- Lymphoid Leukemia in Remission, Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia
- Trial name
- NCT00476047
- Testing
- Tositumomab and Iodine I 131 Tositumomab
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Healthy
Effects of MDMA on Emotional and Social Memories
The purpose of this study is to examine the effects of MDMA on encoding and retrieval of emotional and social memories in healthy young adults.
- Trial name
- NCT03050541
- Testing
- MDMA
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Colonic Carcinoma, Laparoscopic Right Hemicolectomy
Standardizing Right Hemicolectomy for Colon Cancer
A surgical intervention might be highly variable amongst surgeons and centers. This variability has a potential relevance concerning clinical outcomes.
- Conditions
- Colonic Carcinoma, Laparoscopic Right Hemicolectomy, Standardisation, Training
- Trial name
- Right (NCT04889456)
- Testing
- Implementation standardised laparoscopic right hemicolectomy with proctoring, Implementation standardised laparoscopic right hemicolectomy without proctoring
- Where
- Netherlands
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Obstructive Sleep Apnea
Memory Consolidation in Obstructive Sleep Apnea
The overarching goal of the research proposed here is to test the hypothesis (i) that the pathophysiological mechanisms of OSA lead to deterioration in sleep-dependent memory consolidation across memory systems, with the genetic…
- Trial name
- NCT01800786
- Testing
- CPAP
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
Treatment Strategy for Relapsed/Refractory Hodgkin Lymphoma
The choice of the best second-line therapy in patients with high LH R/R risk, it is a niche of knowledge not covered at the moment, especially the role of Brentuximab (BV) plus PD-1 blockade and auto-HSCT.
- Conditions
- Hodgkin Lymphoma, Refractory Hodgkin Lymphoma, Relapsed Hodgkin's Disease, Adult
- Trial name
- NCT05595447
- Testing
- Brentuximab Vedotin 50 MG [Adcetris]
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Sleep
Memory Consolidation in Pharmacologically Enhanced Naps
This study will examine whether various drugs affecting sleep cycles can improve different kinds of memory.
- Trial name
- NCT00777829
- Testing
- zolpidem
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Sleep, Memory
Hypnotic Medications and Memory: Effect of Drug Exposure During the Night
The purpose of this study is to determine the effect of two hypnotic medications, zolpidem extended release and zaleplon, on memory.
- Trial name
- NCT01159652
- Testing
- zaleplon, zolpidem extended release
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Rectal Neoplasms
Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer
Given the growing focus on preserving organ function and the utilization of neoadjuvant therapy, it is important to investigate and enhance the application of comprehensive neoadjuvant therapy in low rectal cancer.
- Trial name
- NCT06417476
- Testing
- Short-course radiotherapy, Irinotecan, Oxaliplatin
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pei-Rong Ding
Locally Advanced Rectal Cancer
Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29
The aim of the ShorTrip trail is to evaluate the activity and the safety of total neoadjuvant strategy with FOLFOXIRI as consolidation therapy preceded by short-course radiotherapy and followed by surgery in LARC patients.
- Trial name
- ShorTrip (NCT05253846)
- Testing
- Irinotecan, Oxaliplatin, Lederfolin
- Where
- Italy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gruppo Oncologico del Nord-Ovest
Healthy Subjects
Effects of Brain Stimulation During Daytime Nap on Memory Consolidation in Younger, Healthy Subjects
The beneficial effect of daytime sleep on memory consolidation has been shown in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent declarative…
- Trial name
- NCT01840865
- Testing
- brain stimulation, no stimulation
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Intrusive Memories
Behavioral Modulation of Intrusive Memories
The purpose of the study is to examine whether sleep affects the development of intrusive memories.
- Trial name
- NCT03227081
- Testing
- Sleep Deprivation
- Where
- Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Posttraumatic Stress Disorder
The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)
The purpose of the study is to learn how differences in learning under mildly-stressful circumstances may be changed by taking oxytocin. Oxytocin is a hormone made naturally in the body.
- Trial name
- NCT01466127
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
PTSD, Intrusive Memories
Estradiol and Intrusive Memories
The aim of the current project is to investigate the impact of 3mg of oral estradiol valerate on the formation of intrusive memories after analog trauma.
- Conditions
- PTSD, Intrusive Memories, Intrusion Symptom, Trauma
- Trial name
- EstraMemo (NCT07419594)
- Testing
- Estradiol Valerate
- Where
- Germany
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Memory Reactivation, Memory Consolidation
Toward a Real-time Access to Sleepers' Mental Content
Sleep is crucial for global cognitive functioning, but its exact functions and mechanisms are still poorly understood. Cognitive studies of sleep typically rely on linking electrophysiological changes measured during sleep with…
- Conditions
- Memory Reactivation, Memory Consolidation, Sleepwalking
- Trial name
- SleepDance (NCT05452733)
- Testing
- differences of behavior between sleepwalking and non sleepwalking patient
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
B-Cell Acute Lymphoblastic Leukaemia
Blinatumomab Consolidation in Real World
This will be a multi-center registry for patients with B-ALL. Patient data will be collected both retrospectively and prospectively.
- Trial name
- NCT07117136
- Where
- 5 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Learning, Humans
Human Learning of New Structured Information Across Time and Sleep
Acting adaptively requires quickly picking up on structure in the environment and storing the acquired knowledge for effective future use.
- Conditions
- Learning, Humans, Consolidation, Sleep
- Trial name
- NCT05910762
- Testing
- Associative inference, Category learning, Sleep
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania