Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
Chronic Obstructive Pulmonary Disease
sTep dOWn Inhalers in the reAl woRlD
To establish the feasibility of stopping inhaled steroids and switching or maintaining dual bronchodilation in one visit - in the real world, for people with COPD.
- Trial name
- TOWARD (NCT03527927)
- Testing
- Any LABA/LAMA
- Where
- United Kingdom
- Volunteers
- 67 people
- Sponsor
- Hywel Dda Health Board
COPD
Implementation of an Evidence Based Smoking Cessation Strategy (SMOCC) for Patients With COPD in Primary Care
A controlled study demonstrated that a smoking cessation protocol in routine primary care, specifically targeted at patients with COPD (SMOCC), doubled the quit rates.
- Trial name
- NCT00294905
- Testing
- Implementation of a combined smoking cessation strategy
- Where
- Netherlands
- Volunteers
- 2,700 people
- Sponsor
- Radboud University Medical Center
COPD Exacerbation
COPD Care Model on Clinical and Patient-Reported Outcomes
This study is the first to evaluate a unique integrated care model for COPD which uses a validated clinical frailty indicator to set care goals and guide health care in hospital and in the community.
- Trial name
- NCT03332394
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Ottawa Hospital Research Institute
COPD, COPD Exacerbation
Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)
This will be a non-blinded feasibility (pilot) study comparing triple therapy nebulizer vs dry powdered inhalers (DPI) for care transitions in Chronic obstructive pulmonary disease (COPD) exacerbation patients.
- Trial name
- NCT03219866
- Testing
- Nebulizers, Dry Powder Inhaler, Brovana
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
Pulmonary Disease, Chronic Obstructive
Study To Evaluate The Efficacy And Safety Of PH-797804 For 12 Weeks In Adults With Moderate To Severe Chronic Obstructive Pulmonary Disease (COPD) On A Background Of Tiotropium Bromide
PH-797804 is an oral anti-inflammatory drug that may reduce the inflammation that is associated with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT01543919
- Testing
- PH-797804
- Where
- 132 sites in United States, Argentina and 12 more
- Volunteers
- 730 people
- Sponsor
- Pfizer
Telerehabilitation, COPD
Telerehabilitation Approaches in Chronic Obstructive Pulmonary Patients
Pulmonary rehabilitation (PR) is a first-line management strategy in chronic obstructive pulmonary patients (COPD) as it reduces shortness of breath, increases exercise capacity, and improves health-related quality of life.
- Trial name
- NCT04694729
- Testing
- videoconference-based, video-based
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Obstructive Pulmonary Disease
Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)
National Institute for Clinical Excellence (NICE) guidelines recommend high dose inhaled steroids for patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD, a common chronic disease related to smoking) who…
- Trial name
- NCT01186653
- Testing
- budesonide / formoterol, fluticasone/salmeterol
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Chronic Obstructive Pulmonary Disease and Allied Conditions
Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease?
This study aims to assess usual walking speed (4-metre gait speed) and markers of sarcopenia predict mortality in patients with chronic respiratory disease.
- Trial name
- NCT02261337
- Where
- United Kingdom
- Volunteers
- 565 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Chronic Obstructive Pulmonary Disease (COPD), Multimorbidities
IMPACT COPD Cohort (China)
Chronic obstructive pulmonary disease (COPD) is a major chronic respiratory condition with high prevalence of multimorbidity. COPD and comorbidities interact dynamically, contributing to symptom fluctuation, acute exacerbations…
- Trial name
- IMPACT (NCT07382986)
- Testing
- Not applicable- observational study
- Where
- 4 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Chao Yang Hospital
COPD
Adverse Health Effects of Mainstream and Secondhand Hookah Smoke in NYC Hookah Bars
The primary purpose of this study is to examine the health effects of mainstream and secondhand hookah (i.e. water pipe) smoke on pulmonary and cardiovascular functions as well as serum levels of inflammatory biomarkers.
- Trial name
- NCT02638194
- Testing
- Active smoking of Tobacco Hookah for 2 hours, Exposure to tobacco hookah second hand smoke, Visit a win bar
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Post Operative Complication, Pulmonary, Lung Cancer
Efficacy of Nebulized Pulmicort Respules in Primary Lung Cancer Patients With COPD
To test the hypothesis that nebulized Pulmicort Respules could reduce post operation pulmonary complication incidence in primary lung cancer patients with COPD.
- Conditions
- Post Operative Complication, Pulmonary, Lung Cancer, COPD
- Trial name
- NCT02504801
- Testing
- Budesonide
- Volunteers
- 73 people
- Sponsor
- Xiuyi Zhi
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The Inspiratory Muscle Activation Pattern and Training Efficacy in Patients With Chronic Obstructive Pulmonary Disease After Acute Exacerbation
The purpose of this study is to assess the activation patterns of diaphragm and sternocleidomastoid (SCM) muscle during different loaded inspiratory muscle performance in patients with COPD after acute exacerbation.
- Trial name
- NCT04316312
- Testing
- Threshold inspiratory muscle trainer
- Where
- Taiwan
- Volunteers
- 1 people
- Sponsor
- National Taiwan University Hospital
Chronic Obstructive Pulmonary Disease
Autologous Bronchial Basal Cells Transplantation for Treatment of Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD) is a kind of chronic bronchitis or emphysema with characteristics of long-term poor airflow, resulting in chronic pulmonary heart disease, chronic respiratory failure or even death.
- Trial name
- NCT03092648
- Testing
- Bronchial basal cell
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Pulmonary Disease, Chronic Obstructive
A 24-week Study to Compare Umeclidinium/Vilanterol (UMEC/VI), UMEC and Salmeterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
COPD is characterized by an airflow limitation, which is not fully reversible, usually progressive and accompanied by chronic cough, sputum production and dyspnea, which can be a major cause of disability and anxiety associated…
- Trial name
- NCT03034915
- Testing
- UMEC/VI 62.5/25 mcg via ELLIPTA, UMEC 62.5 mcg via ELLIPTA, Salmeterol 50 mcg via DISKUS
- Where
- 212 sites in United States, Argentina and 10 more
- Volunteers
- 2,696 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
Utility of Remote Lung Auscultation in Transitions of Care After Pulmonary Exacerbations of COPD
Listening to breath sounds with the stethoscope/auscultation is used by pulmonary physicians in conjunction with pulmonary function, signs and symptoms, oxygen saturation and diagnostic testing to admit, follow and discharge…
- Trial name
- NCT05661435
- Testing
- RESP Biosensor
- Where
- 2 sites in United States
- Sponsor
- Strados Labs, Inc.
Heart Failure, Coronary Artery Disease
COVID-19 Testing in Underserved and Vulnerable Populations
As part of National Institutes of Health Rapid Acceleration of Diagnostics-Underserved Populations (RADx-UP) program, the goal of the RADxUP study is to develop, test, and evaluate a rapid, scalable capacity building project to…
- Conditions
- Heart Failure, Coronary Artery Disease, Cancer, Chronic Kidney Diseases
- Trial name
- NCT05315908
- Testing
- Community outreach method
- Where
- United States
- Volunteers
- 9,120 people
- Sponsor
- Jesse Nodora
COPD (Chronic Obstructive Pulmonary Disease)
Isoinertial Training in Patients With COPD
Isoinertial training is emerging as a potentially effective strategy to improve strength and functionality in older people diagnosed with chronic obstructive pulmonary disease (COPD), due to its influence on muscle mass and…
- Trial name
- ISTrainingCOPD (NCT07605117)
- Testing
- Isoinertial training, Traditional rehabilitation (control group)
- Where
- 2 sites in Colombia
- Volunteers
- 30 people
- Sponsor
- Universidad Manuela Beltrán
COPD
Management of COPD Patients With BoraCare® Remote Monitoring Solution Including BVS3 Early Detection Score for COPD Exacerbations
The goal of this clinical trial is to demonstrate the superiority of remote monitoring with the Bora Care solution in patients with COPD and frequent exacerbations (experimental group) compared to conventional follow-up alone…
- Trial name
- AUSTRAAL (NCT06523140)
- Testing
- Boracare remote monitoring solution
- Where
- 10 sites in France
- Volunteers
- 380 people
- Sponsor
- Biosency
HIV Infections, Emphysema
Prevalence and Pathogenesis of Lung Disease in a Large HIV Cohort-coordinating Center
Despite the availability of highly active antiretroviral therapy (HAART), lung diseases remain a leading cause of morbidity and mortality in those with HIV infection.
- Conditions
- HIV Infections, Emphysema, Chronic Obstructive Pulmonary Disease, Pneumocystis
- Trial name
- MACS (NCT00870857)
- Where
- 2 sites in United States
- Volunteers
- 407 people
- Sponsor
- University of Pittsburgh
COPD, Education
Efficacy of an Education Protocol in the Correction of Inhalation Techniques in COPD
This study evaluates the implementation of an education protocol and its impact on the correct inhalation technique in COPD patients presenting errors or mistakes.
- Trial name
- NCT03144557
- Testing
- Education
- Where
- Argentina
- Volunteers
- 61 people
- Sponsor
- Hospital Italiano de Buenos Aires
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