Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
Pulmonary Disease, Chronic Obstructive
Postmarketing Surveillance Study of Atrovent® Inhalets in Chronic Obstructive Airways Disease
To obtain further information on the tolerability of Atrovent® inhalets in the treatment of Chronic Obstructive Airways Disease under conditions of daily practice
- Trial name
- NCT02238132
- Testing
- ATROVENT® inhalets
- Volunteers
- 374 people
- Sponsor
- Boehringer Ingelheim
COPD (Chronic Obstructive Pulmonary Disease)
RESP-FIT: A Respiratory Muscle Strength Training Intervention for COPD
Individuals with chronic obstructive pulmonary disease (COPD) often experience dyspnea, low physical activity, and reduced quality of life.
- Trial name
- NCT07811219
- Testing
- RESPFIT Intervention
- Volunteers
- 288 people
- Sponsor
- Medical University of South Carolina
Pulmonary Disease, Chronic Obstructive
Advair® DISKUS® Versus Serevent® DISKUS® For Chronic Obstructive Pulmonary Disease Exacerbations
This study evaluates the effect of two medicines on COPD (Chronic Obstructive Pulmonary Disease) exacerbations. This study will last up to 56 weeks, and subjects will visit the clinic 10 times.
- Trial name
- NCT00115492
- Testing
- Fluticasone Propionate/Salmeterol Combination Product, Salmeterol
- Where
- 110 sites in United States, Canada
- Volunteers
- 797 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
A Randomized Controlled Trial to Determine Outcome and Cost Effectiveness of Case Management of Chronic Obstructive Pulmonary Disease (COPD) Patients
This randomized controlled trial (RCT) will examine a nurse case management model for patients suffering from chronic obstructive pulmonary disease (COPD) in a Danish municipality, and is performed in order to evaluate the use of…
- Trial name
- NCT01512836
- Testing
- Case Management
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Kronikerenheden Nordjylland
COPD
Randomized Trial of the FreeAspire Versus PEP-bottle After Acute Exacerbation in COPD Patients
BACKGROUND: Studies have shown that COPD patients with bronchial hypersecretion have increased risk of acute exacerbations. FREE ASPIRE is an electro-medical device which removes bronchopulmonary secretions noninvasively, without…
- Trial name
- NCT02640430
- Testing
- standard treatment, Free Aspire
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 40 people
- Sponsor
- Maugeri Foundation
COPD, Chronic Obstructive Pulmonary Disease
Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients.
The Objectives of this study are to assess the safety of Aclidinium bromide on major adverse cardiovascular events (MACE), to assess the overall safety of Aclidinium bromide and to assess whether Aclidinium bromide reduces…
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease, Moderate to Very Severe COPD
- Trial name
- ASCENT COPD (NCT01966107)
- Testing
- Aclidinium Bromide
- Where
- 468 sites in United States, Canada
- Volunteers
- 3,635 people
- Sponsor
- AstraZeneca
COPD
Daily Magnesium-treatment of Patients With Chronic Obstructive Pulmonary Disease
The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that a daily magnesium supplement will benefit patients with asthma and chronic…
- Trial name
- NCT01118936
- Testing
- Magnesium supplement (magnesium hydroxide/ -oxide)
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- University of Aarhus
COPD, Physical Activity
Physical Activity Following Pulmonary Rehabilitation in COPD
The aim of this feasibility study is to identify the acceptability of an intervention designed to promote physical activity following pulmonary rehabilitation for individuals with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT03660644
- Testing
- WhatsApp, Pedometer and Step Diary
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- University of Lincoln
Copd
Optimizing Self-management COPD Treatment Through the American Lung Association Helpline
Although self-management treatment improves quality of life among individuals with COPD, there is limited understanding of which elements of treatment are most effective.
- Trial name
- NCT05106257
- Testing
- Self-management education (short), Ground-based walking training, Inhaler training
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Rush University Medical Center
COPD
Evaluation of the Reversibility of the Bronchial Obstruction by Impulse Oscillometry Technique in Chronic Obstructive Pulmonary Disease (COPD): Correlation With Functional Features Measured by Plethysmography and Dyspnoea
Limitation of expiratory flows is considered as the main determiner of dynamic distension and dyspnoea in chronic obstructive pulmonary disease (COPD).
- Trial name
- OSCILLOREVERS (NCT02928744)
- Testing
- COPD
- Where
- 2 sites in France
- Volunteers
- 23 people
- Sponsor
- Hopital Foch
Chronic Obstructive Pulmonary Disease, Asthma
Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool
This study is designed to evaluate the effectiveness and implementation of the Assessment of Burden of Chronic Conditions (ABCC)-tool for patients with COPD, asthma, diabetes mellitus type 2 or heart failure (and any combination…
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Diabetes Mellitus, Type 2, Heart Failure
- Trial name
- NCT04127383
- Testing
- Assessment of Burden of Chronic Conditions (ABCC)-tool
- Where
- Netherlands
- Volunteers
- 237 people
- Sponsor
- Maastricht University
Chronic Obstructive Pulmonary Disease
The Effects of Aerobic Exercise Training on Vascular, Cardiac and Cerebral Vascular Function in COPD
The primary cause of chronic obstructive pulmonary disease is smoking, which can lead to inflammation in the lungs and blood vessels that can lead to secondary problems such as blood vessel disease, high blood pressure and heart…
- Trial name
- NCT02875522
- Testing
- Individualized, non-linear aerobic exercise training
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pulmonary Disease (COPD), Chronic Obstructive
Comparison of Arterial and Capillary Blood Gas Analyses in Patients With Respiratory Distress Due to COPD or APE
The assessment of gas exchange is crucial for the management of patients suffering from respiratory distress due to an exacerbation of chronic obstructive pulmonary disease (COPD) or cardiogenic acute pulmonary edema (APE).
- Trial name
- GAZOCAP (NCT07835945)
- Testing
- Capillary blood gas analysis
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Healthy Volunteer, Stroke
Motivation While Doing Physical Exercise in a Social Dual-task Virtual Environment
The goal of this interventional study is to assess the difference in participants' motivation while performing a virtual reality-based dual-task exercise in a single-player vs. multi-player modality.
- Conditions
- Healthy Volunteer, Stroke, COPD, Cerebral Palsy
- Trial name
- ActivE3 (NCT07050654)
- Testing
- Dual-task cycling
- Where
- 4 sites in Italy
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Chronic Obstructive Pulmonary Disease (COPD), Emphysema
Evaluating Genes in Sputum to Measure Drug Response in COPD
The purpose of this research study is to determine whether analysis of genes in sputum is a useful noninvasive technique for measuring response to drugs in patients with COPD.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Emphysema, Chronic Bronchitis
- Trial name
- NCT00233051
- Testing
- Salmeterol or Salmeterol/Fluticasone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Jewish Health
COPD Exacerbation
Emotional-distress-based Integrated Care Programme in Patients With an Acute Exacerbation of COPD
The investigators have developed a new counseling service that focuses on the emotional distress experienced by people living with COPD.
- Trial name
- EmoD (NCT07351929)
- Testing
- EmoD Intervention
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease, Chronic Bronchitis
Determine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects With COPD
The purpose of this study is to assess the bronchodilator effect and safety of multiple daily doses of arformoterol administered for 12 weeks as maintenance treatment in patients with COPD
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema
- Trial name
- NCT00064402
- Testing
- arformoterol tartrate inhalation solution, Salmeterol
- Where
- 65 sites in United States
- Volunteers
- 741 people
- Sponsor
- Sumitomo Pharma America, Inc.
COPD, Asthma
AirSonea Wheeze Detection Study
The purpose of this study is to determine if the AirSonea device provides an objective assessment of breath sounds for the presence of wheeze in both medical and home environments.
- Trial name
- NCT01927172
- Testing
- AirSonea
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- iSonea
COPD
Quality Control and Evaluation in Standard COPD Management
There is lack of quality control and evaluation indexes for standard COPD management in hospitals in China, leading to nonstandard in COPD management and discrepancy in therapeutic efficiency.
- Trial name
- NCT03314077
- Testing
- GOLD 2017
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Tongji Hospital
COPD
The Effect of High Dose N-acetylcysteine on Airtrapping and Airway Resistance in Chronic Obstructive Pulmonary Disease (COPD) Patients
This study is to investigate the add-on effect of high dose NAC (600mg tablet twice daily) on reduction of airtrapping and airway resistance in stable COPD patients as well as to study it's effect in reducing exacerbation…
- Trial name
- NCT01136239
- Testing
- N-acetycysteine (600mg twice daily)
- Where
- China
- Volunteers
- 133 people
- Sponsor
- Kwong Wah Hospital
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