Clinical trials: Pulmonary Disorder, Chronic Obstructive
COPD
Impact of Ibis on Patients With Advanced COPD
The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients with COPD.
- Trial name
- NCT03131622
- Testing
- Digital Therapeutics
- Volunteers
- 240 people
- Sponsor
- Senscio Systems
Copd, Smoking
Clinical Features of Smoker Patients With Chronic Obstructive Pulmonary Disease
Smoking is the most important factor in the etiology of COPD. Some of the patients with COPD continue to smoke despite knowing this situation or they cannot quit even if they want.
- Trial name
- NCT04711629
- Testing
- Clinical Tests
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Chronic Obstructive Pulmonary Disease
Foster® pMDI (CHF 1535) Versus Symbicort® Turbohaler in COPD Patient (FORSYYN)
Primary Objective To demonstrate that CHF 1535 pMDI is non-inferior to Symbicort® Turbohaler® in terms of pulmonary function (change from baseline in pre-dose morning FEV1 at Week 24) in patients with COPD.
- Trial name
- FORSYYN (NCT03888131)
- Where
- 53 sites in China
- Volunteers
- 750 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Copd
Effects of Core Stabilization and Inspiratory Muscle Training in Patients With COPD
In Chronic Obstructive Pulmonary Disease (COPD), a mismatch develops between the respiratory system's demand and the functional capacity of respiratory muscles due to the combination of local and systemic factors increasing the…
- Trial name
- COPD (NCT06510686)
- Testing
- İnspiratory muscle training, Core training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Mustafa Ertuğrul Yaşa
Chronic Obstructive Pulmonary Disease, Type II Diabetes
Mobile Unit Screening of Pathologies Associated With Chronic Diseases - Feasibility
The main objective of this study is to assess the feasibility of standardized screening for comorbidities among patients with one or more of three chronic diseases (diabetes, COPD, atherosclerosis) by a mobile unit at times and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Type II Diabetes, Atherosclerosis
- Trial name
- DéProPAss (NCT02214056)
- Testing
- Patient recruitment, Mobile team exam
- Where
- 13 sites in France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Obstructive Pulmonary Disease
The Effect of Indacaterol on Exercise Endurance in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
This study compared the effect of indacaterol (300 μg once daily [od]) on exercise endurance with that of placebo in patients with moderate to severe chronic obstructive pulmonary disease.
- Trial name
- NCT00620022
- Testing
- Indacaterol 300 μg
- Where
- 20 sites in United States, Belgium and 4 more
- Volunteers
- 90 people
- Sponsor
- Novartis
Chronic Bronchitis
Feasibility Study of the Pulsed Electric Field Ablation System in Treating Chronic Bronchitis
To preliminarily evaluate the safety and feasibility of the pulsed electric field ablation system independently developed by Zhouling (Shanghai) Medical Appliance Co., Ltd. in the treatment of chronic bronchitis.
- Trial name
- NCT05771129
- Testing
- Pulse electric field ablation system developed by Zhouling (Shanghai) Medical Appliance Co., Ltd.
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Jiayuan Sun
COPD
Prevalence of Respiratory Aspiration in Patients With COPD
The aim of the study is to estimate the prevalence of respiratory aspiration in patients with COPD, in a tertiary hospital of Buenos Aires.
- Trial name
- NCT02722629
- Testing
- FEESST
- Where
- Argentina
- Volunteers
- 330 people
- Sponsor
- Hospital Italiano de Buenos Aires
COPD
Feasibility of Noninvasive Trigeminal Nerve Stimulation During Exercise
The purpose of this study is to examine 1) effects of cutaneous electrical trigeminal nerve stimulation (eTNS) on respiratory control in healthy volunteers and 2) explore the potential of this approach to mitigate dyspnea in…
- Trial name
- NCT07686302
- Testing
- Active Stimulation, Fan therapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
COPD
Feasibility of Dance in People With COPD
Despite the benefits associated with individuals with chronic obstructive pulmonary disease (COPD) engaging in pulmonary rehabilitation (PR) programs, the benefits diminish by 6 months.
- Trial name
- NCT03636594
- Testing
- Dance
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- West Park Healthcare Centre
COPD
Study to Determine the Amount of Glycopyrrolate Absorbed in the Lungs After Taking the Medicine With a eFlow Nebulizer and Seebri® Breezhaler® With and Without Activated Charcoal in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).
The purpose of this research study is to determine the amount of medicine absorbed in the lungs following dosing via eFlow nebulizer and Seebri® Breezhaler® with and without activated charcoal in subjects with moderate to severe…
- Trial name
- GOLDEN7 (NCT02512302)
- Testing
- SUN-101 via eFlow nebulizer, SUN-101 via eFlow nebulizer with activated charcoal, Seebri® Breezhaler®
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sunovion Respiratory Development Inc.
COPD, Interstitial Lung Disease
Anxiety Management in Breathlessness.
The goal of this mixed methods study is to learn about cranial electrotherapy stimulation (CES) using Alpha-Stim AID in anxiety related to breathlessness in advanced lung diseases.
- Trial name
- NCT06066658
- Testing
- cranial electrotherapy stimulation (Alpha-Stim AID)
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Leicester
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Pursed-Lip Breathing With Different I:E Ratios on Respiratory Outcomes in COPD Patients
The goal of this clinical trial is to evaluate whether different inspiratory-expiratory (I:E) ratios in the pursed-lip breathing (PLB) technique can improve respiratory outcomes in patients with stable Chronic Obstructive…
- Trial name
- PLB I:E Ratio (NCT07573826)
- Testing
- Participants perform PLB with inspiratory-expiratory ratio 1:3 (2 seconds inspiration, 6 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:4 (2 seconds inspiration, 8 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:5 (2 seconds inspiration, 10 seconds expiration)
- Volunteers
- 122 people
- Sponsor
- Scholastica Fina Aryu Puspasari
Chronic Obstructive Pulmonary Disease
Effects of NIMV on the Health Status of Chronic Obstructive Pulmonary Disease (COPD )Patients
In this proposal, we will implement a randomized controlled trial to determine whether nocturnal NIMV applied for 3 months: 1) improves (disease-specific) health related quality of life (HRQL) of COPD patients compared to a…
- Trial name
- NCT00114426
- Testing
- non-invasive mechanical ventilation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Pulmonary Disease, Chronic Obstructive
Benefits of Epithelial Repair in COPD by Induced Pluripotent Stem Cells (iPS)
The aim of this interventional, cross-sectional and pathophysiological experimental study is to evaluate the potential of a patient's induced pluripotent stem (iPS) cells, used prior to the re-differentiation stage, to enable ex…
- Trial name
- RepCOPDiPS (NCT06755008)
- Testing
- bronchial fibroscopy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Stroke
Brain State-dependent PCMS in Chronic Stroke
After stroke, people often have difficulty using their hands. Combined brain and nerve stimulation can strengthen the neural pathways that control hand function.
- Trial name
- NCT04830163
- Testing
- Brain state-dependent paired corticomotoneuronal stimulation (PCMS)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Texas at Austin
Chronic Obstructive Pulmonary Disease (COPD)
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2)
This is a qualitative research exploration engaging clinical staff at all levels from 10 Practice-Based Research Networks (PBRNs) serving US patient populations of differing gender, racial, ethnic, urban/rural and socio-economic…
- Trial name
- CAPTURE (NCT03653611)
- Testing
- On-site Practice Assessment, Clinical Staff Questionnaires, Patient Opinion Surveys
- Where
- 6 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
COPD
Open Label Study to Assess the Effect of Patient Use and Robustness of Tiotropium 18ug Inhalation Powder, Hard Capsule,Zephir Inhaler Device
An Open Label Study to Assess the Effect of Patient Use and Robustness of Tiotropium 18ug Inhalation Powder, Hard Capsule, Inhaler Device.
- Trial name
- NCT06254664
- Testing
- Tiotropium 18 µg inhalation powder, hard capsule, Zephir inhaler
- Where
- 9 sites in United States, India
- Volunteers
- 116 people
- Sponsor
- Xiromed LLC
Chronic Obstructive Pulmonary Disease
Role of Fibrocytes in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a frequent airway disease characterized by both bronchial inflammation and remodelling. Bronchial mucosa is infiltrated by macrophages, neutrophils and lymphocytes.
- Trial name
- FIREBROB (NCT01196832)
- Testing
- blood sample, Clinical and functional evaluation
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Chronic Obstructive Pulmonary Disease (COPD)
Urolithin A Supplementation During Pulmonary Rehabilitation in Patients With COPD
SUPRA-COPD is a multicenter triple-blind, parallel arm, placebo-controlled randomized controlled trial investigating the efficacy and safety of Urolithin A supplementation during pulmonary rehabilitation in patients with COPD.
- Trial name
- SUPRA-COPD (NCT07871357)
- Testing
- Urolithin A
- Volunteers
- 198 people
- Sponsor
- Bryan A. Ross