Clinical trials: Pulmonary Function Assessment
Fear Anxiety, Pulmonary
Preparation Methods on PFT Performance
Background: Successful spirometry in children depends on adequate cooperation and correct performance of respiratory maneuvers. Although several preparation strategies have been proposed, evidence comparing their effects on both…
- Conditions
- Fear Anxiety, Pulmonary, Performance Assessment
- Trial name
- NCT07713225
- Testing
- Verbal Instruction with Demonstration, Animation-Assisted Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Lung Diseases, Interstitial
Assessment of Neuropsychiatric Function in Patients With Interstitial Lung Disease
Research on the impact of lung diseases on neuropsychological functioning has revealed impaired cognitive processing in patients with a variety of pulmonary disorders.
- Trial name
- NCT05719233
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
COPD, Obstructive Ventilation Disorder
Evaluation of Novel Lung Function Parameters in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the…
- Conditions
- COPD, Obstructive Ventilation Disorder, Pulmonary Emphysema
- Trial name
- NCT02827721
- Testing
- impulse oscillometry, multiple breath washout test, body plethysmography
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Healthy, Healthy Adult
Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Healthy Individuals
To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in healthy individuals, who live…
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07804537
- Testing
- Re-ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
COVID-19
Endothelial Function and COVID-19
The present study aims to investigate the endothelial vasodilator function in patients with COVID-19
- Trial name
- NCT04525443
- Where
- 2 sites in United States, Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hospital San Carlos, Madrid
Cystic Fibrosis
Longitudinal Assessment of Exercise Capacity and Vascular Function in Patients With CF
This project is an attempt to understand how Orkambi treatment affects exercise capacity and the function of the arteries in CF patients who are homozygous F508del.
- Trial name
- NCT03338595
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Augusta University
Healthy
The Effects of Individualized Respiratory Exercise Device in Healthy Individuals
Respiratory exercise devices can be grouped as respiratory muscle training (RMT) devices and incentive spirometers (IS). IS can improve pulmonary ventilation using visual feedback but cannot increase respiratory muscle strength.
- Trial name
- NCT06245928
- Testing
- Individualized Respiratory Exercise Device, Threshold® IMT + Threshold™ PEP
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biruni University
Pediatric Patients With Bronchiectasis
Determination of Physical Fitness Level in Bronchiectasis
The aim of this study is to assess the physical fitness level of children with bronchiectasis. To determine your physical fitness level, we will conduct some game-like tests.
- Trial name
- NCT07121218
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Melis Usul
Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms
GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)
Recently integrated in clinical practice, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification states that a mild (stage I) chronic obstructive pulmonary disease (COPD) is present, in a smoker, when…
- Conditions
- Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms, Physical Activity
- Trial name
- GOLD (NCT01360788)
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Laval University
Covid19
Respiratory Muscle Strength in Volleyball Players Suffered From COVID-19
In literature, there is no data evaluating respiratory functions in volleyball players during Covid-19 pandemic. The aim of this study is to evaluate and compared pulmonary functions, respiratory muscle strength, body…
- Trial name
- NCT04789512
- Testing
- Respiratory functions
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cystic Fibrosis, Portal Hypertension
Portal Hypertension and Systemic Endothelial Function
Cystic fibrosis can affect organs other than the lungs. Liver disease affects about 30% of patients: its main manifestation is the development of portal hypertension (PHT).
- Trial name
- ENDOTH-MUCO (NCT02850692)
- Testing
- measure of endothelial function, Blood sample, Hepatic elastography
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hopital Foch
Cystic Fibrosis
Sweat Evaporimeter Measurement
The investigators hypothesize that measurement of beta adrenergic induced sweat rate using an evaporimeter can accurately and reliably determine different levels of CFTR dysfunction within a spectrum of patients expressing…
- Trial name
- NCT01708655
- Testing
- Sweat Evaporimeter measurement
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Systemic Sclerosis
Non-Invasive Diagnostic and Functional Evaluation of Cardiac Involvement in Patients With Systemic Sclerosis
The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in systemic sclerosis patients and to establish whether it reflects the severity of RV overload.
- Trial name
- NCT00453752
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Emphysema
Smoking Cessation and Functional CT Assessment
The investigators will study the effect of pulmonary arterial vasodilation to see if it eliminates indices of persistent lung injury in smokers that are susceptible to emphysema.
- Trial name
- NCT03382106
- Testing
- Sildenafil 20 MG, Pulse wave velocity, Carotid artery compliance and stiffness
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Eric A. Hoffman
β-Thalassemia, Pulmonary Function
Correlation Between Pulmonary Functions and Physical Fitness in Children With β-thalassemia
The aims of this study are: 1. To determine the correlation between pulmonary functions and physical fitness in children with β-thalassemia. 2.
- Conditions
- β-Thalassemia, Pulmonary Function, Physical Fitness
- Trial name
- NCT05494333
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caregiver, Lobectomy Patient
Physical Activity Intervention Before and After Surgery in Older Adults With Lung Cancer and Their Family Caregivers
This trial studies whether a telephone-based physical activity intervention before and after lung cancer surgery can be provided to older patients and their caregivers.
- Conditions
- Caregiver, Lobectomy Patient, Lung Carcinoid Tumor, Lung Non-Small Cell Carcinoma
- Trial name
- NCT04085081
- Testing
- E-mail, Exercise Intervention, Quality-of-Life Assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Renal Impairment
Renal Impairment Study of PF-07321332 Boosted With Ritonavir in Adult Participants With Renal Impairment and in Healthy Participants With Normal Renal Function.
This is a Phase 1, non-randomized, open-label, 2-part study to investigate the effect of renal impairment on the pharmacokinetics (PK), safety and tolerability of a single oral dose of PF-07321332 in combination with the PK…
- Trial name
- NCT04909853
- Testing
- PF-07321332/ritonavir
- Where
- 5 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pfizer
Post-COVID-19 Syndrome, COVID-19
Evaluation Of The Chronic Effects Of Covıd-19 Infection On The Respiratory System
The aim of this study is to evaluate whether there are chronic effects in the pulmonary system and systemic level in individuals in the post COVID19 period in order to elucidate the involvement of inflammation after recovery.
- Trial name
- NCT06439134
- Testing
- Pulmonary Ultrasound, Respiratory Function Test
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency
Сohort Study to Evaluate Exacerbations, Respiratory Symptoms, Physical Exercise Intolerance and Lung Functions Among Participants Who Use IQOS With Heatsticks Compared to Smokers of Conventional Cigarettes
This study evaluates frequency of exacerbations, respiratory symptoms, physical exercise intolerance and abnormal lung functions among participants who use IQOS with heatsticks compared to smokers of conventional cigarettes
- Conditions
- Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency, Physical Disability, Respiratory Disease
- Trial name
- NCT03383601
- Testing
- Heated Tobacco product IQOS/heatstick, Smoking combustible cigarettes
- Where
- Kazakhstan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Kazakhstan Academy of Preventive Medicine
Group 1: Healthy Controls, Group 2: Stable CF
Assessment of CFTR-Modulator Treatment in Cystic Fibrosis Lung Disease Using Novel Structural and Functional MRI
This is a prospective, longitudinal observational study conducted at The Hospital for Sick Children (SickKids). The purpose of this study is to evaluate the ability of MRI to detect changes in lung structure and function in CF…
- Conditions
- Group 1: Healthy Controls, Group 2: Stable CF, Group 3: CF Participants Anticipated to Receive CFTR-modulator Therapy, Group 4: 4-8 yo CF Participants Starting Triple Combination Modulator Therapy
- Trial name
- NCT04391322
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children