Clinical trials: Pulmonary Lobectomy
Postoperative Pain, Postoperative Complications
A Comparison of Silicone Versus Polyvinylchloride (PVC) Drains Following VATS Lobectomy
The goal of this prospective randomized clinical trial is to compare the impact of the chest tube type on pain, chest drainage efficacy and early postoperative outcome following VATS lobectomy for lung cancer.
- Trial name
- NCT06425601
- Testing
- SIL drain, PVC drain
- Where
- Slovenia
- Volunteers
- 80 people
- Sponsor
- University Medical Centre Ljubljana
Pulmonary Artery Stenosis
Evaluation of Visceral Pleural Lumbar Lymphatic Drainage
Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS).
- Trial name
- SEGPUL (NCT03628326)
- Testing
- Pulmonary arterial tree
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Non Small Cell Lung Cancer
Clinical Outcomes and Quality Of Life After Minimally Invasive Segmentectomy Versus Lobectomy for Lung Cancer
The goal is to compare patient reported outcomes, such as dyspnea, physical functioning and quality of life, between minimally invasive segmentectomy and lobectomy for stage I NSCLC during the first year after surgery.
- Trial name
- NCT07477158
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Pulmonary Complication, Thoracic Surgery
Protective Ventilation During Pulmonary Lobectomy
The investigator will evaluate the influence of lung protective ventilation on postoperative clinical outcome in patients undergoing one-lung ventilation for pulmonary lobectomy.
- Conditions
- Pulmonary Complication, Thoracic Surgery, Inflammation
- Trial name
- NCT03174743
- Testing
- Convential Ventilation 1, Convential Ventilation 2, Protective Ventilation 1
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xuzhou Medical University
Prolonged Air Leak
IBV Valve System for the Treatment of Prolonged Air Leak Under HDE H060002 - Post Approval Study
Study to collect post-market safety data for HUD IBV Valve System, a device to control prolonged air leaks of the lung, or significant air leaks that are likely to become prolonged air leaks following lobectomy, segmentectomy, or…
- Trial name
- HUD-PAS (NCT01166516)
- Testing
- Treatment with HUD IBV Valve System
- Where
- 13 sites in United States
- Volunteers
- 32 people
- Sponsor
- Olympus Corporation of the Americas
Pneumothorax, Pleural Effusion
16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy
The aim of the study is to evaluate postoperative pain in patients receiving a small-bore (16F) chest drain compared to those receiving the standard large-bore (24F) chest drain after minimally invasive pulmonary lobectomy and/or…
- Trial name
- ChestDrain (NCT06958848)
- Testing
- 16 F chest tube, 24 F chest tube, Early removal
- Where
- Switzerland
- Volunteers
- 124 people
- Sponsor
- University Hospital, Basel, Switzerland
Chest Tube
The Affection of Two Chest Management for Enhanced Recovery Program After Video-assisted Thoracoscopic Lobectomy.
Comparing the influences of different chest tube managements for enhanced recovery program after video-Assisted thoracoscopic lobectomy.
- Trial name
- NCT03598296
- Testing
- Large size tube, Drainage ball
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Video Assisted Thoracoscopic Surgery, Thoracic Surgery
Diaphragmatic Thickness and Functional Exercise Capacity in Lobectomy Surgeries With Thoracotomy and VATS
The most commonly treatment for early stage non-small cell lung cancer (NSCLC) is lobectomy. Different surgical interventions during lobectomy are thought to have different effects on respiratory functions and exercise…
- Conditions
- Video Assisted Thoracoscopic Surgery, Thoracic Surgery, Respiratory Muscles
- Trial name
- NCT05669196
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hacettepe University
Non-Small Cell Lung Cancer
SEgmentectomy Versus Lobectomy in T1C Non-Small Cell Lung Cancer (SELTIC)
The goal of this clinical trial is to investigate the role of segmentectomy in clinical T1c (2-3 cm) non-small cell lung cancer (NSCLC). The main questions we aim to answer are: 1.
- Trial name
- SELTIC (NCT06646770)
- Testing
- Segmentectomy, Lobectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Istanbul University - Cerrahpasa
Early Stage Non-small-cell Lung Cancer (Stage 1-2)
Assessment of Ergonomics in 3D vs 2D Thoracoscopic Lobectomy
Video-assisted thoracic surgery (VATS) pulmonary lobectomy is currently widely employed as the first treatment option for surgical management of early stage (stage I-II) non-small-cell-lung-cancer (NSCLC).
- Trial name
- NCT03925103
- Testing
- 3D VATS lobectomy, 2D VATS lobectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Rome Tor Vergata
Lung Cancer
Pulmonary Artery Sealing Using the HARMONIC ACE+ Shears(HS) for VATS Lobectomy
VATS anatomical lung resection provides an effective minimally invasive treatment strategy for stage I and II lung cancer. VATS lobectomy is associated with significantly less postoperative atrial fibrillation, blood transfusion…
- Trial name
- NCT01975623
- Testing
- HARMONIC ACE®+ Shears (HS)
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Cancer, Surgery
Comparison of Sublobar Resection and Lobectomy to Treat Lung Cancer
A multi-center prospective randomized trial in Taiwan to investigate whether sublobar resection, as compared to lobectomy, can offer equivalent clinical results to treat early non-small cell lung cancer.
- Trial name
- NCT03185754
- Testing
- Sublobar resection, lobectomy
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Lung Cancer
A Study to Optimize Care for Lung Cancer Patients Undergoing Video-Assisted Thoracoscopic Surgery (VATS)
This is a research study for participants who have been diagnosed with lung cancer and are receiving VATS (Video Assisted Thoracoscopic Surgery) lobectomy or segmentectomy.
- Trial name
- NCT02502695
- Testing
- VATS-associated best practices
- Where
- 6 sites in United States
- Volunteers
- 173 people
- Sponsor
- Dana-Farber Cancer Institute
Lung Neoplasms, Postoperative Pain
Prospective Randomized Trial Comparing the Effectiveness of Continuous Paravertebral Infusion of Local Anesthetics Versus Intravenous Patient-controlled Analgesia on Acute and Chronic Neuropathic Pain After VATS Lobectomy
Since mid-2000, thoracoscopic lobectomy has been replaced with conventional open lobectomy and it has reduced the operative morbidities and mortalities.
- Trial name
- NCT01703351
- Testing
- 0.5% ropivacaine, Fentanyl 500mcg + acupan 160mg + nasea 0.6mg
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Yonsei University
Lung Cancer Stage I
Outside the Cage (OTC) Robotic Lobectomy
This study consists in a prospective pilot study evaluating the feasibility and safety of OTC RATS lobectomies in patients treated for lung cancer.
- Trial name
- OTC-RATS (NCT05832112)
- Testing
- VATS/RATS lobectomy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Adenocarcinoma
Segmentectomy vs Lobectomy for 2 - 3cm IASLC Grade 1-2 Lung Adenocarcinoma: A Multi-center RCT
This study is a prospective, multicenter randomized controlled trial (RCT) designed to compare the efficacy of segmentectomy and lobectomy for invasive lung adenocarcinoma with a diameter of 2-3 cm and intraoperative frozen…
- Trial name
- STAR012 (NCT07169903)
- Testing
- Pulmonary segmentectomy
- Where
- China
- Volunteers
- 587 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Lung Neoplasms, Surgery
Comparison of Segmentectomy Versus Lobectomy for Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field
This study aims to investigate whether segmentectomy had non-inferiority long-term oncological effects (disease-free survival and overall survival) compared with lobectomy in the treatment of patients with early-stage non-small…
- Trial name
- NCT04944563
- Testing
- Segmentectomy, Lobectomy
- Where
- China
- Volunteers
- 1,120 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Lung Neoplasms
VIdeo Assisted Thoracoscopic Lobectomy Versus Conventional Open LobEcTomy for Lung Cancer
Lung cancer is the leading cause of cancer death worldwide and survival in the United Kingdom (UK) remains amongst the lowest in Europe.
- Trial name
- VIOLET (NCT03521375)
- Testing
- Open Surgery, Video Assisted Thoracoscopic Surgery (VATS)
- Where
- 9 sites in United Kingdom
- Volunteers
- 503 people
- Sponsor
- University of Bristol
Lung Cancer
Fast Tracking in VATS Lobectomy: A Prospective, Historically Controlled, Propensity-Matched Clinical Trial
Currently, at the CHUM - Notre-Dame Hospital, there is no standardized patient care pathway for patients undergoing Video Assisted Thoracic Surgery (VATS) lobectomy.
- Trial name
- NCT02584322
- Testing
- Enhanced Recovery pathway
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Neoplasms, Rehabilitation
Rehabilitation for Thoracoscopic Lobectomy
The main aim of this research is to compare the functional recovery after discharge with the preoperative physical activity as a hypothesis generating study.
- Conditions
- Lung Neoplasms, Rehabilitation, Exercise, Pain, Postoperative
- Trial name
- NCT04502654
- Testing
- Actiwatch 2 (Philips Respironics, Murrysville, USA)
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet