Clinical trials: Pulmonary Resection
Bladder Carcinoma, Prostate Tumor
Validation Study on the Removal of EpCAM-positive Tumour Cells From Blood Collected During Tumour Surgery Using Catumaxomab/Catuvab Device
The REMOVE study was an open-label, multicenter validation study on the removal of EpCAM-positive tumor cells from blood collected during tumor surgery using the CATUVAB Kit.
- Conditions
- Bladder Carcinoma, Prostate Tumor, Gallbladder Carcinoma, Endometrial Carcinoma
- Trial name
- REMOVE (NCT06789224)
- Testing
- CATUVAB
- Where
- 6 sites in Germany
- Volunteers
- 136 people
- Sponsor
- Lindis Bloodcare GmbH
Non-Small Cell Lung Cancer
JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer
To Determine if SAbR improves survival over SR in High Risk Operable Stage I NSCLC
- Trial name
- STABLE-MATES (NCT02468024)
- Testing
- Lung Surgery, Radiation therapy
- Where
- 50 sites in United States, Australia and 2 more
- Volunteers
- 272 people
- Sponsor
- University of Texas Southwestern Medical Center
Non-small Cell Lung Cancer
Pemetrexed/Carboplatin vs Vinorelbine/Carboplatin in Patients With Completely Resected Non-small Cell Lung Cancer (NSCLC)
The main purpose of this randomized phase II trial is to evaluate the clinical feasibility and activity of administering adjuvant chemotherapy of pemetrexed/carboplatin compared with vinorelbine/carboplatin in patients with…
- Trial name
- NCT01258127
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Shanghai Nancy Medical Sci-Tech Co. Ltd
Postoperative Period, Lung Cancer (Diagnosis)
Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery
This randomized controlled clinical trial aims to evaluate the effects of an 8-week tele-yoga intervention in individuals with lung cancer who have undergone lung resection surgery.
- Trial name
- NCT07001670
- Testing
- Tele-Yoga Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Minimally Invasive Surgical Procedures, VATS
Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated.
- Conditions
- Minimally Invasive Surgical Procedures, VATS, RATS Surgery, Pulmonary Lobectomy
- Trial name
- PROTRACT (NCT06638645)
- Testing
- VATS/RATS anatomical lung resection
- Where
- 2 sites in Belgium
- Volunteers
- 140 people
- Sponsor
- University Hospital, Ghent
Lung Cancer, Surgery
Comparison of Sublobar Resection and Lobectomy to Treat Lung Cancer
A multi-center prospective randomized trial in Taiwan to investigate whether sublobar resection, as compared to lobectomy, can offer equivalent clinical results to treat early non-small cell lung cancer.
- Trial name
- NCT03185754
- Testing
- Sublobar resection, lobectomy
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
VATS, Lung
The Comparison of Navigational Bronchoscopic and CT-Guided Preoperative Markings in Minimally Invasive Thoracic Surgery
This clinical trial aims to determine whether navigational bronchoscopic or CT-guided marking is more effective for localizing small pulmonary nodules in minimally invasive thoracic surgery.
- Conditions
- VATS, Lung, ICG (Indocyanine Green)
- Trial name
- NaviGuide (NCT06957600)
- Testing
- Preoperative marking
- Where
- Hungary
- Volunteers
- 66 people
- Sponsor
- Semmelweis University
Hemodynamic Monitoring
Effect of Cardiorespiratory Changes on Carotid Flow Time During Lung Resection Surgery
Cardiorespiratory changes during lung resection surgery, even though generally well tolerated, may lead to hemodynamic compromise, reducing venous return to the heart and hence cardiac output.
- Trial name
- NCT07808749
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Sleeve Gastrectomy, Cholecystectomy
Stanford Program to Accelerate Robotic Children's Surgery
The goal of this clinical trial is to provide additional data to confirm safety and performance of the da Vinci Xi Surgical System in a human clinical setting.
- Conditions
- Sleeve Gastrectomy, Cholecystectomy, Splenectomy, Hysterectomy
- Trial name
- SPARCS (NCT06671639)
- Testing
- da Vinci Xi Robotic Surgery System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Stanford University
Non-Small Cell Lung Cancer
A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection
This is a global study to assess the effects of osimertinib in participants with EGFRm stage IA2-IA3 non-small cell lung cancer following complete tumour resection.
- Trial name
- ADAURA2 (NCT05120349)
- Testing
- Osimertinib
- Where
- 139 sites in United States, Argentina and 18 more
- Volunteers
- 390 people
- Sponsor
- AstraZeneca
Lung Cancer, Nonsmall Cell
Pulmonary Function After Arterial Sleeve Lobectomy
Lung cancer is the leading cause of cancer death worldwide. Despite the evolution of medical and multimodal treatments, surgical treatment remains the curative management in the localized cancer.
- Trial name
- NCT04981938
- Testing
- Lobectomy with pulmonary artery reconstruction
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Régional Universitaire Montpellier
Refractory Pulmonary Tuberculosis
Pimonidazole Hydrochloride to Detect Low Oxygen in Tuberculosis-Infected Lungs
This study will determine whether a drug called pimonidazole hydrochloride shows areas of low oxygen in tuberculosis (TB)-infected lungs.
- Trial name
- NCT00374517
- Testing
- Pimonidazole hydrochloride
- Where
- 2 sites in South Korea
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lobectomy
Tegileridine Combined With Intercostal Nerve Block After Thoracoscopic Lung Resection
Combining tegileridine PCIA with ICNB targeting peripheral nerves, may constitute an ideal analgesic model with complementary advantages.
- Trial name
- NCT07386626
- Testing
- Tegileridine, Intercostal Nerve Block, Sufentanil
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Tongji Hospital
Pancreatic Ductal Adenocarcinoma, Oligometastatic Disease
Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma
Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma (PHOLIPANC). This is an interventional, open-label, non-randomised, single-arm phase II clinical trial.
- Trial name
- NCT06122480
- Testing
- Surgery
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Non-Small Cell Lung Cancer (NSCLC)
A Study In Patients Who Will Undergo Surgical Removal Of Non-Small Cell Lung Cancer To Evaluate Molecular Changes That Occur In Tumor Tissue After Short Term Exposure To PF-00299804
This study will enroll patients who are planned to undergo surgical removal of their tumor. The goal of the study is to evaluate the changes that occur in the tumor after brief (about 8 days) exposure to the study drug.
- Trial name
- NCT00971191
- Testing
- PF-00299804
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pfizer
Lung Cancer
Ventilation Heterogeneity Prior to Lung Resection
This is a single centre prospective six-week observational study to understand the prevalence and clinical relevance of abnormal ventilation of the lung (assessed by Technegas ventilation single photon emission computed…
- Trial name
- NCT04191174
- Testing
- Hyperpolarized 129Xe MRI, Technegas V SPECT, Sputum Induction
- Where
- Canada
- Volunteers
- 115 people
- Sponsor
- McMaster University
Lung Neoplasms
Stereotactic Body Radiotherapy (SBRT) Versus Sublobar Resection for High-Risk Patients Non-Small Lung Cancer
This randomized phase II trial is for medically inoperable early stage non-small cell lung cancer (NSCLC) patients. It is designed to compare the number of patients who are disease free and alive at 2 years between Stereotactic…
- Trial name
- NCT01622621
- Testing
- Sublobar Resection, Stereotactic Body Radiotherapy (SBRT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
ARDS, Human, Ventilator-Induced Lung Injury
Enhanced Lung Protective Ventilation With ECCO2R During ARDS
Acute Respiratory Distress Syndrome (ARDS) is associated with a mortality rate of 30 - 45 % and required invasive mechanical ventilation (MV) in almost 85 % of patients[1].
- Trial name
- PROVE (NCT03525691)
- Testing
- Low flow Extracorporeal CO2 removal
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Hôpital Européen Marseille
Lung Neoplasms
Chemotherapy Treatment in Re-occurring Non Small Cell Lung Cancer (NSCLC) After Previous Chemotherapy and Surgical Removal of the NSCLC Tumor
The purpose of this study is to help answer: Whether pemetrexed, gemcitabine and/or carboplatin can shrink tumor(s) or make tumor(s) disappear in patients with relapsed lung cancer (lung cancer that has come back after surgical…
- Trial name
- NCT00356525
- Testing
- pemetrexed, gemcitabine, carboplatin
- Where
- 17 sites in United States, Brazil and 1 more
- Volunteers
- 41 people
- Sponsor
- Eli Lilly and Company
Lung Cancer
Removal of Lung Nodules After Being Marked With a Microcoil
The objective of this study is to determine if subcentimetre pulmonary nodules can be accurately and safely excised by endoscopic stapling devices after they have been localized using CT and marked with a microcoil device.
- Trial name
- NCT00323089
- Testing
- microcoil insertion and excision
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- University of British Columbia