Clinical trials: Pulmonary Resistance
Prevention of COVID-19
Effects of Surgical Mask Use on Peak Torque, Total Work and Interset Fatigability During Isokinetic Strength Testing
The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmittable person-to-person when an infected individual coughs, sneezes or talks while within at least 6…
- Trial name
- NCT04706299
- Testing
- Resistance Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pathogen Resistance, Pneumococcal Infection
Aerosolized and Intravenous Colistin in Healthy Adults
Colistin is amphipathic, cannot be absorbed from the gastrointestinal tract and is administered intramuscularly, intravenously (IV) or via inhalation.
- Conditions
- Pathogen Resistance, Pneumococcal Infection, Pneumonia
- Trial name
- NCT01863719
- Testing
- Colistimethate sodium
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pulmonary Disease, Healthy
Reliability of Different FOT Devices to Measure the Human Respiratory Impedance
The objective of the study is to evaluate the reliability of the impedance data in adult subjects measured with five different FOT devices.
- Trial name
- NCT01868607
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
High Altitude, Healthy
Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals
To study the effect of a re-ascent after a one-week stay at sea level (after prior descent from 2850m) to high altitude (Quito Ecuador: 2850m) on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in healthy…
- Conditions
- High Altitude, Healthy, Healthy Adult, High Altitude Effects
- Trial name
- NCT07804589
- Testing
- Re-Ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Early Adult Lung Function, Small Airway Disease
Factors Affecting Early Adult Lung Function
Attainment of peak healthy lung function during the 18-26 yr window is a strong determinant of the rate of lung function decline during the later years of life.
- Conditions
- Early Adult Lung Function, Small Airway Disease, Metabolic Syndrome
- Trial name
- FEAL (NCT03187158)
- Testing
- Forced Oscillation Technique
- Where
- India
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Council of Scientific and Industrial Research, India
COVID-19 Pandemic
Effects of Diagrammatic Breathing With and Without Resistance in Post Covid Patients on ADLs
Effects of diaphragmatic breathing exercise with and without resistance exercise program on functional capacity and activity of daily living in post covid patients
- Trial name
- NCT05543551
- Testing
- Diaphragmatic breathing with Resistance Training, diaphragmatic breathing with out resistance training
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Covid19, Personal Protective Equipment
Rational Use of Personal Protective Equipment During COVID-19 Pandemic
This study aims to improve the personal protective equipment (PPE) used while treating patients with COVID-19, to protect staff and avoid cross-infection of patients.
- Trial name
- RUPERT (NCT04712045)
- Testing
- New PPE, Old PPE
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Rifampicin-Resistant Pulmonary Tuberculosis Patients
Drug-Drug Interaction and Food Effect of Sudapyridine(WX-081) With Itraconazole and Rifampin in Healthy Chinese Adults
The goal of this clinical trial is to learn how Sudapyridine (WX-081) tablets interact with other drugs and how food intake affects its pharmacokinetics in healthy Chinese adults.
- Trial name
- WX081-DDI (NCT06701136)
- Testing
- Sudapyridine, Itraconazole, Rifampin
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiatan Pharmatech Co., Ltd
Allergic Rhinitis, Asthma
Leukotriene D4 Nasal Provocation Test in Allergic Rhinitis
Leukotrienes play critical roles in the inflammatory process in allergic rhinitis and bronchial asthma, therefore, anti-leukotriene therapy is part of treatment for asthma.
- Trial name
- NCT01963741
- Testing
- leukotriene D4, histamine
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Pulmonary Arterial Hypertension, Heart Failure
Effects of Apelin on the Lung Circulation in Pulmonary Hypertension
The purpose of this study is to determine the effects of Apelin on the lung circulation. The investigators hypothesise that Apelin will relax the lung blood vessels and improve the pumping ability of the heart.
- Trial name
- NCT01457170
- Testing
- Apelin
- Where
- 3 sites in United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
Nasal Polyps, Asthma
Assessment of Oral and Nasal Breathing With Sensors Analyzing Algorithm
The goal of this observational study is to learn about the agreement between sensors analyzing algorithm and body plethysmography in measuring oral and nasal breathing in healthy adults, and in patients with chronic…
- Conditions
- Nasal Polyps, Asthma, COPD, Allergic Rhinitis
- Trial name
- NCT05869071
- Testing
- Sensor analyzing software (own development), Body plethysmograph
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Insulin Resistance, Decreased Pulmonary Function
Associations of Exposure to Phthalates With Insulin Resistance and Epigenetic Change
Phthalate is an endocrine disrupting chemical, which works as an anti-androgenic agent. Phthalate is mainly used as PVC plasticizer and easily found in commonly used products such as electronic device, paint, lubricant…
- Trial name
- NCT02284477
- Testing
- non- PVC containing packing materials, PVC containing packing materials
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Covid19, Obesity
COVID-19, Aging, and Cardiometabolic Risk Factors Study
COVID-19 pandemic has made a tremendous impact on Indonesian economic and health care system especially with the double burden of diseases facing by Indonesia as a developing country.
- Conditions
- Covid19, Obesity, Diabetes Mellitus, Aging
- Trial name
- CARAMEL (NCT04802044)
- Where
- 2 sites in Indonesia
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pulmonary Disease, Chronic Obstructive
Breathing With a Facemask Exercise Performance
This study will determine the dyspnea response in chronic lung disease volunteers during treadmill walking with and without added inspiratory resistance.
- Trial name
- NCT05633017
- Testing
- CereVu Objective Dyspnea Score
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- CereVu Medical, Inc.
Lung Diseases, Pulmonary Disease
A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis
Although Cystic Fibrosis is a complex genetic disease affecting many organs, lung disease is the primary cause of mortality. The objective of this study is to determine the safety and tolerability of SNSP113 in healthy subjects…
- Conditions
- Lung Diseases, Pulmonary Disease, Cystic Fibrosis, Cystic Fibrosis Lung
- Trial name
- NCT03309358
- Testing
- Inhaled SNSP113
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Synspira, Inc.
Smoking
Effect of Lower Limb Resistance Versus Endurance Training in Smokers
Patients was selected based on inclusion and exclusion criteria. Experimental group was treated with Resistance training while control group received endurance training.
- Trial name
- NCT06674174
- Testing
- lower limb strength training, endurance training
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Insulin Resistance
Insulin- and Glucose Metabolism in Pulmonary Arterial Hypertension
Insulin resistance is a key mechanism in metabolic disorders, which has also been implicated in the development of pulmonary hypertension.
- Trial name
- NCT03584607
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Obesity, Metabolic Syndrome
Exercise Capacity and Dyspnea in Obese Patients With Metabolic Syndrome: Effects of Weight Loss
Dyspnea is a common complaint in obese patients. The mechanisms behind this dyspnea and the effects of weight loss on dyspnea are not completely understood.
- Trial name
- NCT03035149
- Testing
- Weight Management Program
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Iron-deficiency, Ventricular Function
Iron Status and Cardiopulmonary Physiology
This study involved human volunteers undertaking a high-altitude expedition. It assessed changes in physiological parameters of relevance to high-altitude cardiopulmonary physiology.
- Conditions
- Iron-deficiency, Ventricular Function, Pulmonary Vascular Resistance Abnormality, Altitude Hypoxia
- Trial name
- NCT03707249
- Testing
- Ferric Carboxymaltose Injectable Product, Normal Saline 0.9% Infusion Solution Bag
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Royal Centre for Defence Medicine
Metabolic Syndrome, Overweight and Obesity
Age-related Post-lockdown BMI Variations
The COVID-19 lockdown has represented an unedited model of increased metabolic risk in all age groups, due to negative changes in dietary habits, physical activity, lifestyle.
- Trial name
- COVIDLOCKMET01 (NCT05430542)
- Where
- Italy
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of Bari