Clinical trials: Pulpitis
Irreversible Pulpitis, Caries,Dental
Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth
The aim of the study is to evaluate effectiveness of cinnamon extract versus sodium hypochlorite as root canal irrigant for in pulpectomy of primary teeth in reduction of bacterial count .
- Trial name
- NCT05860712
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Effect of Passive Ultrasonic Irrigation Activation Cycle on Postoperative Pain
One of the most important goals of root canal treatment is to eliminate bacteria from infected canals. However, conventional irrigation methods combined with mechanical preparation applied during root canal treatment may not be…
- Trial name
- NCT06711029
- Testing
- Conventional needle irrigation, Passive Ultrasonic Irrigation with 3*20 sn, Passive Ultrasonic Irrigation with 6*10 sn
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Esin Özlek
Irreversible Pulpitis
Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis
To compare the effect of different VPT methods using Calcium Enriched Mixture (CEM) cement for management of human dental pulp with irreversible pulpitis.
- Trial name
- NCT01561183
- Testing
- Indirect pulp capping (IPC), Direct pulp capping (DPC), Miniature pulpotomy (MP)
- Where
- Iran
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Symptomatic Irreversible Pulpitis
Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis
The purpose of this study is to evaluate the success of inferior alveolar nerve block, after the local application of Mepivacaine plus Tramadol in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT02110966
- Testing
- Mepivacaine, Mepivacaine plus Tramadol
- Where
- Mexico
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Postoperative Pain
Comparative Evaluation of the Effect of Prophylactic Intraligamentary Injection of Dexamethasone and Piroxicam on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis
the study is conducted to assess and compare the efficacy of local intraligamentary injection of glucocorticoids(dexamethasone) and NSAID(piroxicam) on reduction of postoperative pain in patients with symptomatic irreversible…
- Trial name
- NCT03745105
- Testing
- Dexamethasone sodium phosphate, Piroxicam Injectable Solution, Mepivacaine HCL
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo
Aim. To compare the outcome of preoperative administration of single-dose ketorolac, non-steroidal anti-inflammatory drug and placebo on postoperative pain in teeth with irreversible pulpitis and apical periodontitis.
- Trial name
- PreOp (NCT03116672)
- Testing
- one dose ketorolac 10 mg, One dose Diclofenac
- Where
- Mexico
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Pain
Comparison of Post Operative Endodontic Pain in Patients With Irreversible Pulpitis Treated With and Without Dexamethasone.
Root canal procedure is a common procedure in dentistry. Acute inflammatory response in peri-radicular tissues after root canal treatment is the main cause of post op pain.
- Trial name
- NCT06432712
- Testing
- Dexamethasone 4mg
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shoaib Rahim
Irreversible Pulpitis
Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents
The goal of this clinical trial is to to compare effect of wound lavage agents NaOCl and Chlorhexidine on the outcome of partial pulpotomy in mature permanent posterior teeth with signs and symptoms indicative of irreversible…
- Trial name
- NCT06240130
- Testing
- Partial pulpotomy
- Where
- India
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Reversible Pulpitis
Direct Pulp Capping Agent on Human Pulp Tissue
This in- vivo study was conducted to evaluate the response of human pulp tissue following direct pulp capping using four different pulp capping agents in premolars scheduled for extraction in patients undergoing orthodontic…
- Trial name
- NCT06435065
- Testing
- Biodentine, Mineral Tri-Oxide Aggregate, THERACAL LC
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DR SURINDER SACHDEVA
Symptomatic Irreversible Pulpitis
Assessment of Pain and Treatment Success After VPT Versus RCT in Mature Permanent Mandibular Molars With SIP: A RCT
Assessment of postoperative pain and treatment success after vital pulp therapy versus root canal treatment in mandibular molar with signs and symptoms of irreversible pulpitis.
- Trial name
- NCT05681494
- Testing
- Root canal treatment, Vital pulp therapy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Comparing the Outcome of Pulpotomy Using Biodentine and Portland Cement in Mature Cases With Irreversible Pulpitis: Randomized Clinical Trial
The aim of the study is to compare the treatment outcome of pulpotomy using Biodentine or Portland cement regarding success rate and post-operative pain.
- Trial name
- NCT04573374
- Testing
- Pulpotomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Postoperative Dental Pain, Pulp Disease, Dental
Effect of Different Apical Actions on Local Inflammatory Mediators and Pain
The goal of this clinical trial is to determine patients' the inflammation and pain response to different apical actions used in rotary instrumentation during root canal shaping process.
- Conditions
- Postoperative Dental Pain, Pulp Disease, Dental, Pulpitis - Irreversible
- Trial name
- NCT06760312
- Testing
- Root canal shaping with Continuous Rotation, Root canal shaping with Apical Reverse, Root canal shaping is conducted with Apical slow-down kinematic.
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Symptomatic Irreversible Pulpitis
Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teeth and Premolars in Symptomatic Irreversible Pulpitis
Symptomatic irreversible pulpitis is a painful condition that requires anesthesia to perform effective dental procedures. The mental nerve block and inferior alveolar nerve block are two commonly used techniques for achieving…
- Trial name
- NCT06333730
- Testing
- inferior alveolar nerve block, mental nerve block
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prime Foundation
Pulpitis
Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis
Ninety patients with irreversible pulpitis diagnostic will participate in this clinical study. The participants will be divided into 2 groups of 45 patients, who will receive the inferior alveolar nerve block injections of 1.8 mL…
- Trial name
- Volumes (NCT02422823)
- Testing
- Articaine, Epinephrine
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Isabel Peixoto Tortamano
Deep Caries, Pulpitis Reversible
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults.
- Conditions
- Deep Caries, Pulpitis Reversible, Pulp Hyperemia
- Trial name
- NCT05816525
- Testing
- Partial removal of carious tissue, Final restoration
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Irreversible Pulpitis, Tooth Extraction
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.
- Trial name
- NCT06245161
- Testing
- Quicksleeper5, conventional anesthesia
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pulpitis
Efficacy of Combining an Inferior Alveolar Nerve Block With a Buccal Infiltration
OBJECTIVE To compare the effectiveness of using both a combined technique of an Inferior Alveolar Nerve block and buccal infiltration with that achieved by utilizing an Inferior Alveolar Nerve block alone for endodontic treatment…
- Trial name
- NCT06276842
- Testing
- Inferior Alveolar Nerve Block, Buccal Infiltration, Inferior Alveolar Nerve Block and Buccal Infiltration
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CIMS Dental College
Pain, Postoperative
Comparison of Post-operative Pain After Using Different File Systems
To compare the postoperative pain in patients undergoing root canal instrumentation with two different file systems, WaveOne and ProTaper systems.
- Trial name
- NCT06665152
- Testing
- ProTaper File System, WaveOne File System
- Where
- Pakistan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Ahmed Abdullah
Drug Effect, Pulpitis - Irreversible
Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis
This is a randomized controlled trial comparing the anaesthetic efficacy of 1.8 and 3.6 mL of Articaine for inferior alveolar nerve block when treating mandibular molars with Irreversible Pulpitis
- Trial name
- IANB (NCT05840913)
- Testing
- Articaine HCl 4 % / EPINEPHrine 1:100,000 in 1.8 mL Dental Cartridge
- Where
- 2 sites in Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan