Clinical trials: Pulpitis
Pulpitis - Irreversible, Anesthesia, Local
Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success
The purpose of this study is to assess the effect of preoperative Diclofenac Potassium (50 mg Cataflam) on the anesthetic success of buccal infiltration with 4% articaine with epinephrine 1:200,000 in mandibular molars with…
- Trial name
- NCT03174860
- Testing
- Diclofenac Potassium 50mg Tab
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Vital Pulp Therapies, Tooth Defect
Assessment of the Number of Missing Tooth Surfaces and the Molecular Findings on the Outcomes of Vital Pulp Therapy Using Two Calcium Silicate Materials
The present study aimed to evaluate and compare the clinical and radiographic outcomes of full pulpotomy in mandibular molar teeth with symptomatic irreversible pulpitis according to: A.
- Trial name
- VPT (NCT06787742)
- Testing
- full pulpotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Irreversible Pulpitis
Comparing the Outcome of Pulpotomy Using Biodentine and Portland Cement in Mature Cases With Irreversible Pulpitis: Randomized Clinical Trial
The aim of the study is to compare the treatment outcome of pulpotomy using Biodentine or Portland cement regarding success rate and post-operative pain.
- Trial name
- NCT04573374
- Testing
- Pulpotomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulpitis - Reversible, Occlusal Caries
Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay
pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels
- Conditions
- Pulpitis - Reversible, Occlusal Caries, Proximal Caries
- Trial name
- NCT07171229
- Testing
- Pulpotomy, Measuring Cytokines level
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Postoperative Dental Pain, Pulp Disease, Dental
Effect of Different Apical Actions on Local Inflammatory Mediators and Pain
The goal of this clinical trial is to determine patients' the inflammation and pain response to different apical actions used in rotary instrumentation during root canal shaping process.
- Conditions
- Postoperative Dental Pain, Pulp Disease, Dental, Pulpitis - Irreversible
- Trial name
- NCT06760312
- Testing
- Root canal shaping with Continuous Rotation, Root canal shaping with Apical Reverse, Root canal shaping is conducted with Apical slow-down kinematic.
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Symptomatic Irreversible Pulpitis
Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teeth and Premolars in Symptomatic Irreversible Pulpitis
Symptomatic irreversible pulpitis is a painful condition that requires anesthesia to perform effective dental procedures. The mental nerve block and inferior alveolar nerve block are two commonly used techniques for achieving…
- Trial name
- NCT06333730
- Testing
- inferior alveolar nerve block, mental nerve block
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prime Foundation
Irriversible Pulpitis
Postoperative Pain After Root Canal Treatment Using Different Root Canal Sealers
This prospective randomized clinical trial aims to compare the effects of three different root canal sealers-AH Plus, ProRoot Bio Sealer, and BC Sealer ion+-on postoperative pain following root canal treatment in patients…
- Trial name
- PO-Pain (NCT07608939)
- Testing
- AH Plus Root Canal Sealer, ProRoot Bio Sealer, BC Sealer ion+ Sealer
- Where
- Cyprus
- Volunteers
- 135 people
- Sponsor
- European University of Lefke
Pulpitis
Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis
Ninety patients with irreversible pulpitis diagnostic will participate in this clinical study. The participants will be divided into 2 groups of 45 patients, who will receive the inferior alveolar nerve block injections of 1.8 mL…
- Trial name
- Volumes (NCT02422823)
- Testing
- Articaine, Epinephrine
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Isabel Peixoto Tortamano
Cryotherapy
Effect of Two Different Cryotherapy Irrigation Protocols on Postoperative Endodontic Pain
The aim of this study is to evaluate the effect of intracanal cryotreated (2-3°C) 2.5% sodium hypochlorite and Saline used throughout the procedure, compared with a room-temperature irrigation protocol with a final cryotreated…
- Trial name
- NAOCL/EDTA (NCT07676409)
- Testing
- Full Cryotherapy Irrigation (FC), Final Flush Cryotherapy Irrigation (FFC), Conventional Irrigation (CI)
- Volunteers
- 45 people
- Sponsor
- Cairo University
Deep Caries, Pulpitis Reversible
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults.
- Conditions
- Deep Caries, Pulpitis Reversible, Pulp Hyperemia
- Trial name
- NCT05816525
- Testing
- Partial removal of carious tissue, Final restoration
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Irreversible Pulpitis, Pulpotomy
R. Officinalis as Pulpotomy Agent in Permanent Teeth With Irreversible Pulpitis
This study evaluates and compares the clinical and radiographic outcomes of Rosmarinus officinalis and Mineral Trioxide Aggregate (MTA) when used as pulpotomy medicaments in vital mature permanent teeth with irreversible…
- Conditions
- Irreversible Pulpitis, Pulpotomy, MTA Vital Tooth Pulpotomy
- Trial name
- NCT07610057
- Testing
- MTA Pulpotomy, Rosemarinus officinalis extract pulpotomy
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Irreversible Pulpitis, Tooth Extraction
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.
- Trial name
- NCT06245161
- Testing
- Quicksleeper5, conventional anesthesia
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pulpitis
Efficacy of Combining an Inferior Alveolar Nerve Block With a Buccal Infiltration
OBJECTIVE To compare the effectiveness of using both a combined technique of an Inferior Alveolar Nerve block and buccal infiltration with that achieved by utilizing an Inferior Alveolar Nerve block alone for endodontic treatment…
- Trial name
- NCT06276842
- Testing
- Inferior Alveolar Nerve Block, Buccal Infiltration, Inferior Alveolar Nerve Block and Buccal Infiltration
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CIMS Dental College
Pulpitis - Irreversible
Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy Medicaments in Primary Teeth
when caries reaches the pulp of the tooth, it has to be removed and replaced with a material. In this study im examining the clinical and radiographic signs and symptoms after using different natural materials in pulpotomized…
- Trial name
- RCT (NCT04719247)
- Testing
- Pulpotomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Pain, Postoperative
Comparison of Post-operative Pain After Using Different File Systems
To compare the postoperative pain in patients undergoing root canal instrumentation with two different file systems, WaveOne and ProTaper systems.
- Trial name
- NCT06665152
- Testing
- ProTaper File System, WaveOne File System
- Where
- Pakistan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Ahmed Abdullah
Pulpitis - Reversible, Pulpotomies on Primary Molars
Pelargonium Graveolens Essential Oil as a Pulpotomy Agent in Primary Teeth
The success of pulpotomy in primary teeth is critical for preserving function and arch integrity in children and depends largely on the biological properties of the medicament used.
- Trial name
- NCT07386925
- Testing
- pulpotomy, Radiation
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Symptomatic Irreversible Pulpitis
Full Pulpotomy in Mature Teeth With Symptomatic Irreversible Pulpitis as a Routine Treatment in the Primary Care Clinics
The present study has the objective of being a first approach of the full feasibility study in order to find out whether the Full Pulpotomy performed by a general practice dentist in a primary care dental clinic at the public…
- Trial name
- NCT05199181
- Testing
- Full pulpotomy
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- Rubén Domínguez Pérez
Drug Effect, Pulpitis - Irreversible
Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis
This is a randomized controlled trial comparing the anaesthetic efficacy of 1.8 and 3.6 mL of Articaine for inferior alveolar nerve block when treating mandibular molars with Irreversible Pulpitis
- Trial name
- IANB (NCT05840913)
- Testing
- Articaine HCl 4 % / EPINEPHrine 1:100,000 in 1.8 mL Dental Cartridge
- Where
- 2 sites in Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Dental Pain, Pulpitis
Evaluation of Pulpal and Salivary Neuropeptides in Dental Pain
This observational cross-sectional study is designed to evaluate pulpal and salivary levels of Substance P (SP) and Calcitonin Gene-Related Peptide (CGRP) in individuals with and without dental pain.
- Conditions
- Dental Pain, Pulpitis, Pulpal Inflammation, Psychological Stress
- Trial name
- PAIN-SPCGRP (NCT07330024)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Kahramanmaras Sutcu Imam University