Clinical trials: Pulpitis - Irreversible
Postoperative Pain
Effect of Pretreatment Dexamethazone on Pain and Success of Nerve Block
A Comparative Evaluation of the effect of pretreatment dexamethasone versus placebo on post-endodontic pain and success of inferior alveolar nerve block in Mandibular molars with symptomatic Irreversible Pulpitis: A Blinded…
- Trial name
- NCT03199482
- Testing
- Dexamethasone Oral Tablet
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator
Patients with painful molars will be randomly assigned to 2 different groups: GentleWave and EndoActivator. The root canals will be completed using identical protocols except in the mode of delivery and activation of irrigation…
- Trial name
- NCT04552132
- Testing
- Multisonic vs Sonic activation of irrigants
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Symptomatic Irreversible Pulpitis
Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain
The aim of this study is to determine whether inferior alveolar nerve block of ketorolac and lidocaine would improve the success rate in teeth with symptomatic irreversible Pulpitis.
- Trial name
- IANB (NCT03410212)
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Postoperative Dental Pain, Pulp Disease, Dental
Effect of Different Apical Actions on Local Inflammatory Mediators and Pain
The goal of this clinical trial is to determine patients' the inflammation and pain response to different apical actions used in rotary instrumentation during root canal shaping process.
- Conditions
- Postoperative Dental Pain, Pulp Disease, Dental, Pulpitis - Irreversible
- Trial name
- NCT06760312
- Testing
- Root canal shaping with Continuous Rotation, Root canal shaping with Apical Reverse, Root canal shaping is conducted with Apical slow-down kinematic.
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Teeth With Acute Irreverseble Pulpitis
Evaluation of the Effect of Intra-ligamentary Injection of Diclofenac Potassium Versus Articaine on Anaesthetic Efficacy in Mandibular Molars With Symptomatic Irreversible Pulpitis.
This study aims to assess the effect the intraligamentary injection of Diclofenac Potassium versus Articaine 4% on the anaesthetic efficacy \& intensity of intraoperative \& postoperative pain during single visit root canal…
- Trial name
- NCT06500871
- Testing
- Diclofenac Potassium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy
The efficacy of short course orally administered dexamethasone on the reduction of pain before conventional pulpotomy has not yet been demonstrated.
- Trial name
- NCT05761730
- Testing
- Dexamethasone Oral
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- May Samaha
Pulpitis
Use of Tramadol Intraligamentary Injections
Introduction: To achieve painless treatment in patients with a failed primary IANB, supplementary anaesthesia has been advised. The majority of the studies evaluating intraligamentary injections have been performed on…
- Trial name
- NCT05538052
- Testing
- Tramadol hydrochloride, Lidocaine Hydrochloride
- Where
- India
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Pulpitis - Irreversible, Pulpitis - Reversible
Observational Cross-sectional Study Aiming to Determine the Correlation Between Pulpal Status and IL-8 and Presepsin Levels in the Pulpal Blood.
Observational cross-sectional study aims to determine the correlation between pulpal status and IL-8 and Presepsin levels in the pulpal blood.
- Trial name
- Cross-section (NCT07466095)
- Testing
- IL-8 and Presepsin levels in the pulpal blood.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vital Pulp Therapy
Comparative Evaluation of Three Pulpotomy Agents for Permanent Mature Molars With Irreversible Pulpitis
Statement of the problem: Accurate pulpal diagnosis is essential for decision making between vital pulp therapy and root canal treatment.
- Trial name
- NCT06232941
- Testing
- Full pulpotomy procedure
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Irreversible Pulpitis
Comparing MTA Pulpotomy to Root Canal Treatment in Management of Permanent Molars With Irreversible Pulpitis in Children
Dental caries, highly prevalent amongst children, can cause pulpitis. Coronal pulpotomy provides an easier, cost-effective, conservative and biologically-driven treatment option compared to endodontic treatment in mature…
- Trial name
- NCT06488131
- Testing
- MTA Pulpotomy, Root Canal Treatment
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Irreversible Pulpitis, Apical Periodontitis
Evaluation of iRoot SP as Root Canal Sealer: A Clinical Study
The purpose of this study was to evaluate the clinical and radiological outcomes of iRoot SP as a root canal sealer in comparison with AH Plus sealer within 1-year follow up.Patients needing root canal treatment were enrolled and…
- Trial name
- NCT02981693
- Testing
- Root canal sealer
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Hui Chen
Irreversible Pulpitis
Partial Pulpotomy in Mature Permanent Teeth With Signs and Symptoms of Irreversible Pulpits
The main purpose of the present study is to assess the outcome of partial pulpotomy by using two different bioactive materials, namely MTA [MTA Angelus (Angelus, Londrina, Brazil) and Total Fill BC putty (FKG, La Chaux-de-Fonds…
- Trial name
- NCT04870398
- Testing
- Vital Pulp therapy-Partial pulpotomy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Post-operative Pain, Pulpitis - Irreversible
Evaluation of Post-operative Pain After Total Pulpotomy and Root Canal Treatment
The aim of this study was to compare post-operative pain following total pulpotomy (TP) and root canal treatment (RCT) in mature molar teeth with severe symptoms indicative of irreversible pulpitis.
- Trial name
- NCT05923619
- Testing
- Total pulpotomy, Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Endodontic Treatment, Irreversible Pulpitis
A Clinical Study: the Antibacterial Effect of Insoluble Antibacterial Nanoparticles (IABN) Incorporated in Dental Materials for Root Canal Treatment
The effect of Antibacterial Nanoparticles, Incorporated in root canal sealer material and in provisional restoration is going to be examined.
- Conditions
- Endodontic Treatment, Irreversible Pulpitis, Health Pulp, Infected Pulp
- Trial name
- IABN (NCT01167985)
- Testing
- IABN
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Irreversible Pulpitis
Assessment of L-PRF, Nanohydroxyapatite Combined With L-PRF Using Pulpotomy in Mature Mandibular First Molars
Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.
- Trial name
- NCT06613932
- Testing
- pulpotomy
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Endodontic Inflammation, Pulp Disease, Dental
Evaluation of Clinical and Radiological Success of Vital Amputation Treatment
Total amputation therapy; is a treatment method aimed at maintaining the vitality of the radicular pulp remaining as a result of complete removal of coronal pulp tissue.
- Trial name
- NCT03883295
- Testing
- Control, NeoMTA Plus
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Endodontic Inflammation
Comparison Between the Vibringe and the Conventional Needle
The Vibringe is the first endodontic sonic irrigation system that enables delivery and activation of the irrigation solution in the root canal, in only one step.
- Trial name
- NCT03551587
- Testing
- Vibringe
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Extremely Deep Caries
Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy
The aim of this randomised control trial is to compare the effect of different concentrations of NaOCl on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.
- Conditions
- Irreversible Pulpitis, Extremely Deep Caries, Partial Pulpotomy
- Trial name
- NCT06433245
- Testing
- effect of 3% and 5% sodium hypochlorite on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.
- Where
- India
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis
Effect of Occlusal Reduction on Post-operative Pain
effect of occlusal reduction on post-operative pain is evaluated after single visit root canal treatment in upper and lower molar teeth in patients with sypmtomatic irreversible pulpitis and apical periondontis
- Conditions
- Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis, Apical Periodontitis
- Trial name
- NCT03189771
- Testing
- occlusal surface reduction
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
Background The European Society of Endodontology (ESE) and the American Association of Endodontists (AAE) position statements on the management of deep caries and exposed pulp recommended adoption and promotion of strategies…
- Trial name
- NCT06002698
- Testing
- Root canal treatment (Control), Full pulpotomy (Experimental)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya