Clinical trials: Punctal Stenosis
Management of Punctal Stenosis
Topical Cyclosporin A 0.05% Eye Drops for Management of Symptomatic Acquired Punctal Stenosis. A Prospective, Controlled Clinical Study.
A prospective, controlled, interventional clinical study, includes all patients (16 years) with symptomatic epiphora and diagnosed with grade 1 or grade 2 acquired punctal stenosis.
- Trial name
- NCT05771012
- Testing
- 0.05% cyclosporin (Restasis®, Allergan Inc), mini-monoka stent
- Where
- Kuwait
- Volunteers
- 42 people
- Sponsor
- Farwaniya Hospital
Epiphora
Placement of Three Interrupted Sutures After Triangular Three-snip Punctoplasty
a prospective randomized study conducted upon 40 eyes of 24 patients with lower punctual stenosis (grade 1 or 2 according to Kashkouli scale) attending at Menoufia University hospitals and Kafr Elsheikh ophthalmic eye center.
- Trial name
- NCT04680078
- Testing
- Placement of three interrupted sutures after Triangular Three-snip Punctoplasty of the lower punctum, Conventional Triangular Three-snip Punctoplasty of the lower punctum
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Epiphora, Punctal Stenosis
A Comparative Analysis of the Effectiveness of Nepafenac Combined With a Lubricant Versus a Lubricant Alone in the Treatment of Epiphora Associated With Lacrimal Punctum Stenosis
Establish the efficacy of combined treatment with nepafenac and lubricant versus lubricant alone in improving epiphora and resolving punctal stenosis in Mexican adults.
- Trial name
- CAENLVLTELPMA (NCT07372014)
- Testing
- Nepafenac and lubricant
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Punctal Stenosis
Comparison Between Mini Monaka,Perforated Plugs and 3-Snip Punctoplasty in Punctal Stenosis
To compare the result of mini monaka to perforated plug and 3 snip punctoplasty in management of punctal stenosis.
- Trial name
- NCT06446674
- Testing
- mini monaka
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Ophthalmopathy , Lacrimal System
Evaluation of Lacrimal Punctal Changes by Anterior Segment Optical Coherence Tomography AS-OCT After Topical Combined Antibiotics and Steroids Treatment in Cases of Inflammatory Punctual Stenosis
Punctal stenosis is an important etiological factor that should be considered when assessing patients with epiphora. Anatomically, acquired punctal stenosis is a condition in which the external opening of the lacrimal canaliculus…
- Trial name
- NCT05028907
- Testing
- 5 mg chloramphenicol, 1 mg dexamethasone sodium phosphate, 0.25 mg tetryzoline hydrochloride, 2 mg Hydroxypropyl Methyl Cellulose, 10 mg α-tocopherol acetate and 8 mg macrogol 400)., sodium hyaluronate, polyethylene and propylene glycol based) three times daily for three months
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Sohag University
Epiphora
Topical Cyclosporine-A for Management of Epiphora
to investigate the clinical outcomes and tolerances of Cyclosporine A (CsA) in treating epiphora in eyes with acquired punctum stenosis
- Trial name
- CSA-epiphora (NCT04637633)
- Testing
- topical 0.05% CsA (Restasis®, Allergan Inc, Irvine, California)twice daily dose,
- Where
- Kuwait
- Volunteers
- 12 people
- Sponsor
- Farwaniya Hospital
Epiphora
Management of Lower Punctal Stenosis.
a prospective non-randomized study conducted upon 24 patients with severe lower punctual stenosis (grade 0 according to Kashkouli scale) attending at Menoufia University hospitals. The upper punctum and canaliculus were patent.
- Trial name
- NCT03731143
- Testing
- insertion of self retaining bicanalicular stent
- Volunteers
- 24 people
- Sponsor
- Menoufia University
Epiphora Due to Insufficient Drainage
OCT Guided Punctal Stenosis Management
This is a clinical trial study that was conducted on patients with punctal stenosis.We studied the diameter of stenosed puncta before and after treatment with preserved free steroid eye drops using AS-OCT.
- Trial name
- NCT04318652
- Testing
- Methylprednisolone eyedrops
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Punctal Stenosis
AS OCT Evaluation for Perforated Punctual Plugs
Evaluation of the perforated punctal plugs after implantation in cases of punctal stenosis regarding position and patency in the early postoperative period (during the first operative weak)
- Trial name
- NCT04624022
- Testing
- Anterior segment optical coherent tomography
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Lacrimal Stenosis of Both Eyes
Lacrimal Deroofing for Epiphora
Puncto-canalicular abnormalities, such as obstruction and canaliculitis, are a significant cause of epiphora. They involve proximal lacrimal drainage system.
- Trial name
- NCT06983717
- Testing
- lacrimal deroofing
- Where
- United Arab Emirates
- Volunteers
- 39 people
- Sponsor
- Benha University
Punctal Stenosis
3 Snip Punctoplasty With and Without Mitomycine C.
Punctal stenosis is a progressive constriction of the puncta with resultant epiphora. One of the most effective treatment options is 1- to 4-snip punctoplasty combined with or without Mitomycin-C.
- Trial name
- NCT05586620
- Testing
- 3-snip punctoplasty, 3-snip punctoplasty and Mitomycin C
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University
Punctal Stenosis
Diagnosis of Acquired Punctal Stenosis Using Anterior Segment Optical Coherence Tomography
Purpose of the study To evaluate the lower puntum dimensions in cases of acquired punctal stenosis(APS), using anterior segment optical coherence tomography (AS-OCT).
- Trial name
- NCT03498144
- Testing
- Anterior segment OCT
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Modalities, Treatment
Three Different Modalities for Treatment of Inflammatory Punctal Stenosis
This study aimed to compare the efficacy of three various modalities of treatment of inflammatory punctal stenosis (Punctal dilatation alone, combined punctal dilatation with topical medications, or peri-punctal injection of…
- Conditions
- Modalities, Treatment, Inflammatory Punctal Stenosis
- Trial name
- NCT06798025
- Testing
- Punctal dilation, Punctal dilation and topical medication, Triamcinolone acetonide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Epiphora, Conjunctivitis
Perforated Punctal Plugs for Treatment of Papillary Conjunctivitis in Otherwise Healthy Patients
Assessing efficacy of punctal dilatation with insertion of perforated punctal plugs for the management of acquired punctal stenosis due to allergic conjunctivitis in otherwise healthy patients.
- Trial name
- NCT02503956
- Testing
- Perforated Punctal plugs, Crawford tube insertion, Crawford lacrimal tube
- Where
- Israel
- Volunteers
- 14 people
- Sponsor
- Rabin Medical Center