Clinical trials: Puncture
Papain, Itch
Characterization of New Human Models of Non-histaminergic Itch
In this experiment the investigators would like to test a new new human itch model based on papain, and to characterize the sensory quality and temporary aspects of papain skin prick test (SPT) in comparison to the…
- Conditions
- Papain, Itch, Skin Prick Test (SPT)
- Trial name
- NCT04515056
- Testing
- Papain 10 µg, Papain 50 µg, Papain 100 µg
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Evaluation of the Radiofrequency Transseptal Puncture System, Atrial Septum Puncture
Prospective, Multicenter, Randomized Controlled, Non-inferior Clinical Study to Evaluate the Safety and Efficacy of Radiofrequency Transseptal Puncture System in Atrial Septul
To evaluate the safety and efficacy of radiofrequency transseptal puncture system and its auxiliary radiofrequency puncture device in atrial septum.
- Trial name
- NCT06990230
- Testing
- Radiofrequency Transseptal Puncture System and Auxiliary Device
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Post-Dural Puncture Headache
The Sphenopalatine Ganglion Block for Post-dural Puncture Headache
This study aims to determine the efficacy of the sphenopalatine ganglion block in the treatment of post-dural puncture headache in post-partum women at the Brigham and Women's Hospital by measuring VAS scores at times between 0…
- Trial name
- NCT03385772
- Testing
- Sphenopalatine ganglion block
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anesthetic Regional Techniques for Vaginal Surgeries
Regional Anesthesia
Both techniques are efficacious for sacral anesthesia during vaginal surgeries. Dural puncture epidural technique allows partial confirmation of epidural catheter placement.
- Trial name
- NCT04933500
- Testing
- Whitacre spinal needle
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Allergic Rhinitis, Asthma
Evaluation and Validation of Novel Diagnostic Tool for Allergists (AbioSCOPE)
In this study, investigators evaluated for the first time the diagnostic efficacy of abioSCOPE® versus Phadia Laboratory System as an aid in the diagnosis of allergic diseases.
- Trial name
- NCT03599908
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Ultrasound Therapy; Complications
Utility of Ultrasound-Guided Site Marking in Pediatric Lumbar Punctures
The standard way to identify landmarks in the spine before inserting a needle for a lumbar puncture is to feel by touch. The purpose of this research is to determine if doing an ultrasound to identify landmarks before performing…
- Trial name
- NCT04828746
- Testing
- Ultrasound Guided Skin Marking
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Pain, Fear
The Effect of Virtual Reality and Buzzy Application on Pain, Fear and Anxiety During Prick Test in Children
Allergy is a hypersensitivity reaction to a triggering agent. Tests used in allergy are divided into two: in vivo and in vitro. Among the in vivo tests routinely used, epidermal, intradermal and patch tests are used, and the most…
- Conditions
- Pain, Fear, Anxiety, Children, Only
- Trial name
- NCT06443060
- Testing
- Virtual Reality Group, Buzzy Application Group, Control Group
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Obstetric Pain, Labor Pain
Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia
The purpose of this prospective randomized controlled study is to compare the number of physician top-up interventions during the first stage of labour between two different neuraxial analgesia techniques : the dural puncture…
- Conditions
- Obstetric Pain, Labor Pain, Anesthesia
- Trial name
- DPE (NCT04728048)
- Testing
- Dural puncture epidural, Standard epidural
- Where
- Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Venous Puncture Pain
Investigating the Impact of Ice Application on the Venous Puncture Pain in the Pediatric Population
the goal of this RCT is: "To evaluate the effectiveness of a non-pharmacological method (ice application) in reducing venous puncture pain among children aged 5 to 7 years.".
- Trial name
- NCT06089889
- Testing
- ice application, control group
- Where
- Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Gynecologic Diseases Requiring Vaginal Hysterectomy
Dural Puncture Epidural Technique For Vaginal Procedures
25G Dural Puncture Epidural Technique will be compared with Conventional Standard Lumbar Epidural Technique During Anesthesia of Laparoscopic Assisted Vaginal Hysterectomy.
- Trial name
- NCT05031117
- Testing
- Conventional Epidural Technique, 25G Dural Puncture Epidural Technique
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Venous Puncture
Comparison of Figure-Of-Eight Suture Perclose ProGlide Suture-Mediated Closure
The study proposes to compare specialized closure devices to achieve hemostasis with the Figure-of-eight suture technique.
- Trial name
- NCT04831008
- Testing
- Figure-of-eight suture, Perclose Device
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Delray Medical Center
Food Allergy Suspected
Comparison of Skin Prick Testing, Extract-specific IgE Antibody Testing and Component Resolved Diagnosis in Diagnosing of Legume Allergy
The study is aimed at improving the diagnosis of food allergy, specifically allergy to commonly consumed legumes such as peas, lentils, chickpeas or green beans.
- Trial name
- CRD (NCT06923878)
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Pilsen
Alzheimer Disease
Evaluation of a Finger Prick Collection Method for Measuring Alzheimer's Disease Blood Biomarkers
This is an observational study that will collect blood from a finger prick (Capitainer SEP10 single channel device) and assess the accuracy of pTau-217 testing in comparison to previously collected venous blood samples from the…
- Trial name
- eDROP-AD (NCT07187921)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Banner Health
CSF Leak, CSF Pressure Increased
Conservative vs Interventional Management of Postsurgical CSF Pseudomeningocele
Dear Sir or Madam, You have been invited to participate in a clinical study whose aim is to compare the effectiveness of two different approaches to the treatment of cerebrospinal fluid (CSF) pseudomeningocele - conservative…
- Conditions
- CSF Leak, CSF Pressure Increased, CSF Circulation Disorder, Puncture
- Trial name
- PSEUDO (NCT07614399)
- Testing
- Lumbar Drainage, Pseudomeningocele Puncture, Puncture with Fibrin Glue Application
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Temperature, Blood Flow Velocity
Effect of Cryotherapy Modalities on Skin Temperature, Radial Artery Size and Flow Where Arterial Puncture Are Performed
Low-intervention clinical trial. The thermal and hemodynamic effects of different cryotherapy devices are evaluated. This study is included in the doctoral thesis of the principal investigator.
- Conditions
- Temperature, Blood Flow Velocity, Radial Artery Size
- Trial name
- ECCRIOGAS (NCT05915234)
- Testing
- Crushed ice, Frozen peas, Room temperature gel
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Julio Alberto Mateos Arroyo
Measurements of Areas of Secondary Hyperalgesia
Delineating Areas of Secondary Hyperalgesia: Influence of the Assessment Method
Assessments of mechanical skin sensitivity include psychophysical responses to stimulation with calibrated polyamide monofilaments.
- Trial name
- NCT02286037
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Pain, Anxiety
Effect of Virtual Reality and Serious Games on Pain, Fear, Anxiety, and Satisfaction During Skin Prick Testing in Children
This randomized controlled trial evaluated the effectiveness of virtual reality (VR) and serious gaming (SG) in reducing pain, fear, and anxiety, and improving satisfaction during skin prick testing (SPT) in children aged 6-12…
- Conditions
- Pain, Anxiety, Fear, Allergy
- Trial name
- NCT06993259
- Testing
- Virtual Reality, Serious game
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University