Clinical trials: Pupil Diameter
Normal Non-fluency, Cataract
Comparative Study of the Optical Biometer for Measurements of the Eye
The primary purpose of this comparative clinical study is to collect clinical data to demonstrate the equivalence of the investigational device to the predicate device for measurements of the eye.
- Conditions
- Normal Non-fluency, Cataract, Aphakic Eye, Eyes With Corneal Abnormality
- Trial name
- NCT01729962
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Retinopathy of Prematurity
Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical Study
Retinopathy of prematurity (ROP) is one of the common anatomic causes of blindness among Filipinos, accounting for 47.7% of the cases.
- Trial name
- NCT04838665
- Testing
- 0.5% cyclopentolate and 2.5% phenylephrine, 0.5% tropicamide + 0.5% phenylephrine, 0.5% tropicamide + 0.5% phenylephrine with a cotton wick
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the Philippines
Chronic Pain Due to Injury
Effects of Intramuscular (IM) Oxytocin on Pupil Diameter and Heart Rate Variability (HRV)
The goal of this study is to test the effects of oxytocin on heart rate variability and pupil diameter, both of which have subtle effects on the activity rate of the autonomic nervous system.
- Trial name
- NCT04105998
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep Apnea Syndrome, Obstructive, Drowsiness
Ocular Parameters in Patients With Sleep Apnea
The aim of this study is to assess the ocular parameters of drowsiness in patients with diagnosed Obstructive Sleep Apnea Syndrome through objective methods of ocular imaging and subjective evaluation methods (questionnaire)
- Conditions
- Sleep Apnea Syndrome, Obstructive, Drowsiness, Blinking, Concentration Ability Impaired
- Trial name
- NCT05911737
- Testing
- Short video and Questionnaire
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Measurement of Pupil Diameter
Effects of Sevoflurane and Propofol on Light Flash Evoked Pupillometry
Null hypothesis (HO): There will be no difference in pupillometry readings when using any of the maintenance anesthetic techniques within subjects.
- Trial name
- NCT00695890
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
Healthy
Effect of Brimonidine Tartrate Ophthalmic Solution 0.15% on Pupil Diameter in Normal Eyes
The objective of this study is to evaluate the effect of brimonidine tartrate ophthalmic solution 0.15% (Alphagan P) on pupil diameter under different luminance conditions.
- Trial name
- NCT00413751
- Testing
- Brimonidine tartrate ophthalmic solution 0.15% (Alphagan P)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
no Condition, Electroencephalography
Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation
This study investigates the capacity of non-invasive vagus nerve stimulation, applied at the ear, to alter to measures of locus coeruleus output pupil diameter and EEG alpha power.
- Conditions
- no Condition, Electroencephalography, Pupil Diameter
- Trial name
- NCT04455295
- Testing
- Transdermal Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Arkansas Tech University
Pupil Diameter, Arousal
Effects of the Ultra-low Frequencies TENS on the Arousal Circuits
Pupil size is associated with the activity of the noradrenergic system, with an increase reflecting a higher state of arousal. Transmucosal electrical stimulation of the tongue could treat disorders related to dysfunctions of…
- Trial name
- NCT06790459
- Testing
- UlfTens (Ultra-low-frequencies Transcutaneous electrical nervous stimulation)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Measurement of Pupil Diameter
Comparison of Two Different Pupillometer
With the development of refractive surgery, the size of scotopic pupil has been widely concerned by clinicians. Historically, the measurement of pupil size included the use of a pupil ruler, which is known for its drawback of…
- Trial name
- NCT05717244
- Testing
- 2WIN-S, OPD
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- He Eye Hospital
Healthy
The Effect of Topical Treatment With Combigan Compared to Timolol and Brimonidine on Pupil Diameter
In this study we will explore the combined effect of Brimonidine and Timolol 0.5% (Combigan) eye drops on pupil dilation. It is a well studied phenoma that Brimonidine and a miotic effect on the pupil, however the combined effect…
- Trial name
- NCT02214680
- Testing
- Combigan (Combination of Brimonidine and Timolol), Timolol
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center