Clinical trials: Quadriceps Muscle Function
Muscle Weakness
Electrical Stimulation to Strengthen Muscles in the Lower Legs in Patients Requiring Prolonged Mechanical Ventilation
The primary aim of this proposal is to test the effectiveness of NMES in improving functional status and muscle function in patients requirng prolonged mechanical ventilation
- Trial name
- NCT01825135
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- RML Specialty Hospital
ACL - Anterior Cruciate Ligament Rupture
Optimizing Graft Selection for ACL Reconstruction
Purpose: To investigate the differences between the three most common methods for reconstruction of the anterior cruciate ligament (ACL), to support the development of the best method for the individual patient.
- Trial name
- GRASE-ACL (NCT05342441)
- Testing
- QT graft, ST/Gr graft, BPTB graft
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Hvidovre University Hospital
COPD, COPD Exacerbation
Ultrasonographic Evaluation of Diaphragm and Quadriceps in Chronic Obstructive Pulmonary Disease (COPD) Patients
The purpose of this study is to evaluate the prognostic role of echographic diaphragmatic assessment and vastus lateralis muscle ultrasound (US) in two independent populations of patients hospitalized for exacerbated Chronic…
- Trial name
- EDIFEB (NCT04509128)
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele Roma
Quadriceps Muscle Function
Central and Peripheral Changes in Quadriceps Femoris Function After Different Types of Isometric Strength Training
The purpose of this investigation is to examine the effects of 6-week unilateral isometric training interventions over quadriceps femoris on maximal strength and RFD-SF parameters and cortical excitability.
- Trial name
- NCT04624438
- Testing
- Isometric training with electromyostimulation, Isometric training with voluntary activation, Isometric training with combination of electromyostimulation and voluntary activation
- Where
- Serbia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms
GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)
Recently integrated in clinical practice, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification states that a mild (stage I) chronic obstructive pulmonary disease (COPD) is present, in a smoker, when…
- Conditions
- Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms, Physical Activity
- Trial name
- GOLD (NCT01360788)
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Laval University
Osteoarthrosis
Effect of Methylprednisolone on Quadriceps Muscle Function in Patients Undergoing Total Knee-arthroplasty
This study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total knee-arthroplasty (TKA).
- Trial name
- NCT02319343
- Testing
- Methylprednisolone, Isotonic Sodium Chloride
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
ACL - Anterior Cruciate Ligament Deficiency, ACL Injury
Tourniquet Use in Anterior Cruciate Ligament Repair
The purpose of this study is to assess the intra-operative and post-operative effects of tourniquet use during ACL reconstruction. We hypothesize that: 1.
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, ACL Injury, ACL Tear
- Trial name
- NCT05931627
- Testing
- Patients undergoing ACL reconstruction with or without a tourniquet
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Healthy Volunteers, Neuromuscular Function
Eco-guided Neuromodulation of the Femoral Nerve on the Performance of Amateur Athletes.
This randomized crossover study aims to evaluate whether different percutaneous electrical nerve stimulation (PENS) protocols produce changes in neuromuscular performance in healthy adults.
- Trial name
- NCT07719179
- Testing
- Theta Burst Protocol, 10-10-10 Protocol, 5-55 Protocol
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Knee Osteoarthritis
Effect of Hip Abductors Versus Knee Extensor Strengthening in Knee Osteoarthritis
This study will try to answer the following question: Would strengthening of hip abductors be equal to, or more effective than, knee extensors strengthening in improving pain, function and knee extensors isometric strength in…
- Trial name
- NCT04503304
- Testing
- Exercises
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Patellofemoral Pain Syndrome
Quadriceps Strengthening At Different Angles in Patellofemoral Pain
Introduction: Patellofemoral pain (PFP) is characterized by anterior, retropatellar and/or peripatellar pain during activities such as running, squatting, kneeling, or prolonged sitting.
- Trial name
- NCT06502795
- Testing
- Protected Range Quadriceps Strengthening group, Patient-Guided Range Quadriceps Strengthening group
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Universidade Federal do Ceara
ACL Tears
Characterizing Clinical and Biomechanical Contributions to Function Following ACL Reconstruction
Quantify differences in quadriceps function and gait biomechanics in individuals within 2 years of ACL reconstruction compared to a healthy comparison group and establish the feasibility of conducting a progressive strengthening…
- Trial name
- NCT03132987
- Testing
- Progressive strengthening program
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Creighton University
Patello Femoral Syndrome
The Effect of Patellar Taping and Isometric Strength Training on Quadriceps Strength with Patellofemoral Pain Syndrome.
Patellofemoral pain syndrome is one of the most common young adult female complaints, caused by changes in the patellofemoral joint's physical and biomechanical properties.
- Trial name
- NCT05168332
- Testing
- patellar taping combined with isometric strength training
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Majmaah University
Patellofemoral Disorder, Anterior Knee Pain Syndrome
Efficacy of Patellar Taping and Electromyographic Biofeedback Training at Various Knee Angles on Quadriceps Strength and Functional Performance in Patellofemoral Pain Syndrome
This study compared the effects of patellar taping and electromyographic-biofeedback (EMG-BF) guided isometric quadriceps strengthening at different knee angles in patello-femoral pain syndrome (PFPS).
- Trial name
- NCT05055284
- Testing
- Electromyographic-biofeedback guided (EMG-BF) isometric quadriceps strengthening with patellar taping five days a week for six weeks.
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Burns, Muscle Weakness
Reallocating Rehabilitation Time to Wii Fit or Pilates After Lower-Limb Burn Injury
This randomized controlled trial will evaluate whether reallocating part of a fixed-duration supervised rehabilitation session to Wii Fit or Pilates will improve functional outcomes in adults with healed lower-extremity burns.
- Conditions
- Burns, Muscle Weakness, Exercises, Functional Performance
- Trial name
- NCT06081504
- Testing
- Wii fit exercises program, Pilates exercises program, Standard physical therapy program
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Knee Arthritis Osteoarthritis, Balance Assessment
Popliteus and Quadriceps Muscle Thickness and Clinical Parameters in Knee Osteoarthritis
This study aims to examine the relationships between the ultrasonographic muscle thicknesses of the popliteus and quadriceps muscles and functional capacity, balance, and pain levels in elderly patients with knee osteoarthritis…
- Trial name
- NCT07834827
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Afyonkarahisar Health Sciences University
Muscle Strength Development, Muscle Strength
Acute Effects of Proprioceptive Neuromuscular Facilitation on Hamstring-to-Quadriceps Strength Ratio
This study aimed to compare the acute effects of proprioceptive neuromuscular facilitation (PNF) and static stretching on hamstring-to-quadriceps (H/Q) strength ratios in healthy young men.
- Conditions
- Muscle Strength Development, Muscle Strength, Neuromuscular Function
- Trial name
- Acute Effects (NCT07589712)
- Testing
- PNF Stretching, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Emphysema
Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment
Rationale: Chronic obstructive pulmonary disease (COPD) is characterised by a high prevalence of peripheral muscle dysfunction, which can have significant clinical consequences, including decreased exercise capacity, reduced…
- Trial name
- ENDURANCE (NCT06025500)
- Testing
- 31P-Magnetic Resonance Spectroscopy (31P-MRS)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Vascular Remodeling, Sedentary Behavior
Effect of Training Intensity on Microvascular Function
The aim of this trial is to investigate the effect of aerobic training intensity on muscle vascular function: continuous versus interval.
- Conditions
- Vascular Remodeling, Sedentary Behavior, Hemodynamic Rebound
- Trial name
- NCT07237854
- Testing
- Percutaneous muscle biopsies of the vastus lateralis (quadriceps), Measurement of the maximal oxygen uptake (VO2max), Non-Invasive Cardiac Output Measurement (Innocor)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Osteoarthritis, Knee, Exercise
The Effect of Contralateral Isokinetic Lower Extremity Exercises in Unilateral Painful Knee Osteoarthritis
Patients with unilateral knee pain due to knee osteoarthritis presenting to our clinic will be included in a 20-session treatment program, either on an outpatient basis or as inpatients at our clinic.
- Trial name
- NCT06675318
- Testing
- Cross training for quadriceps muscle of contralateral lower limb, Quadriceps isometric exercises, along with hot pack and TENS for painful knee
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Gazi University
Intensive Care Unit Acquired Weakness, Muscle Weakness
Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasive Mechanical Ventilation
Patients in intensive care often develop acquired muscle weakness (ICUAW or Intensive Care Unit Acquired Weakness) due to immobilization and muscle atrophy.
- Trial name
- DYNAMOREA (NCT07069959)
- Testing
- Early assessment of quadriceps muscle strength
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital