Clinical trials: Quality of Life Outcomes
Prostate Cancer (Adenocarcinoma), Radical Prostatectomy
Evaluation of Pelvic Floor Function and Psychosocial Sequelae Following Radical Prostatectomy for Prostate Cancer
This observational cross-sectional study aims to evaluate the effects of radical prostatectomy for prostate cancer on pelvic floor function and psychosocial well-being.
- Conditions
- Prostate Cancer (Adenocarcinoma), Radical Prostatectomy, Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- NCT07693647
- Testing
- No Interventions
- Where
- Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Sedentary Lifestyle, Workplace
Effectiveness of a Workplace "Sit Less and Move More" Web-based Program in Spanish Office Employees (Walk@WorkSpain)
This study assesses the short and mid-term impacts of a workplace web-based intervention (Walk@WorkSpain, W@WS) on self-reported occupational sitting time, step counts, activity-related energy expenditure, physical risk factors…
- Conditions
- Sedentary Lifestyle, Workplace, Quality of Life, Intervention Study
- Trial name
- W@WS (NCT02960750)
- Testing
- A workplace "sit less and move more" web-based program for Spanish office employees, Active Comparison group
- Where
- 4 sites in Spain
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06570993)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Hemophilia A
Health-Related Quality of Life Outcomes and Bleeding Rates Among Patients With Severe Hemophilia A on Emicizumab
The main purposes of this study are to determine if use of emicizumab prophylaxis treatment reduces number of bleeding episodes, if it improves quality of life of individuals and if improves arthropathy in persons with hemophilia…
- Trial name
- ML43518 (NCT06104826)
- Testing
- Emicizumab
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Newark Beth Israel Medical Center
Patient Experience, Medical Emergencies
Effectiveness and Clinical Outcomes of Municipal Acute Wards Versus a General Hospital
Demographic changes in the industrialized world are expected to prompt a need for better organized and more efficient health care services.
- Conditions
- Patient Experience, Medical Emergencies, Mortality, Morbidity
- Trial name
- NCT03885206
- Testing
- Level of healthcare services
- Where
- Norway
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Ostfold University College
Dyslipidemias
The Influence of Pilates Exercises Training Volume on Metabolic Outcomes in Dyslipidemic Women.
The aim of the present study was to assess the influence of different volumes of Pilates training exercises on metabolic, blood pressure (BP), functional physical fitness (PF) and quality of life (QL) outcomes in postmenopausal…
- Trial name
- NCT03307031
- Testing
- High Volume Group, Low Volume Group, Control Group
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Breast Implant; Complications, Quality of Life
An Analysis of Adverse Events and Satisfaction Outcomes of Women Who Underwent Primary and Secondary Breast Augmentation Using Silimed® Breast Implants
The study investigates the safety and performance of Silimed® silicone gel breast implants with a textured surface and Silimed® silicone gel breast implants with polyurethane coated surface.
- Conditions
- Breast Implant; Complications, Quality of Life, Satisfaction
- Trial name
- STEPS A (NCT03356132)
- Testing
- Silimed® Textured Silicone Gel-Filled Breast Implant, Silimed® Polyurethane Foam Covered Silicone Gel-Filled Breast Implant
- Where
- Brazil
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Cerclage, Cervical, Cervical Insufficiency
Long-Term Patient-Reported Maternal Outcomes Following Abdominal Cerclage for the Prevention of Preterm Birth
This study aims to explore the maternal patient reported outcomes on pelvic pain sexual health anxiety and depression bladder discomfort foreign body sensation trust in the cerclage, and how these parameters affect the general…
- Trial name
- NCT06875401
- Testing
- Abdominal cerclage (open or laparoscopic)
- Where
- Denmark
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Scleroderma, Systemic, Scleroderma, Diffuse
Exercise With Scleroderma Functional Outcomes
The study aims to investigate the effects of an exercise program applied to patients with scleroderma on functional outcomes (hand and mouth functional results and quality of life).
- Conditions
- Scleroderma, Systemic, Scleroderma, Diffuse, Scleroderma, Limited, Hand Rheumatism
- Trial name
- NCT06425653
- Testing
- Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Trakya University
Cerebral Palsy
Serious Games for Serious Outcomes: Enhancing Cognition, Balance, and Quality of Life in Children With Cerebral Palsy
Children with cerebral palsy (CP) often face challenges with balance, movement, and skills such as memory, problem-solving, and attention. These difficulties can affect not only daily activities but also their quality of life.
- Trial name
- Games4CP (NCT07158424)
- Testing
- Serious games, Intensive rehabilitation, Physical therapy
- Where
- Ukraine
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nataliya Hrabarchuk
Unilateral Primary Osteoarthritis of Hip
Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
The aim of this study is to investigate the clinical outcome of the two different, but widely used, surgical approaches (Posterior approach and Lateral approach) of primary total hip arthroplasty in patients diagnosed with…
- Trial name
- COMPALA (NCT01616667)
- Testing
- Total hip arthroplasty
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Congenital Heart Disease, Comorbidities and Coexisting Conditions
Congenital Heart Initiative-Redefining Outcomes and Navigation to Adult Centered Care
Congenital heart defects (CHDs) are a heterogeneous group of rare diseases of varying severity, each diagnosis with its unique set of co-morbidities.
- Trial name
- CHI-RON (NCT05185232)
- Testing
- Impact of gaps in care/loss to healthcare follow-up
- Where
- 16 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Breast Cancer, Quality of Life
The PreQ-20 TRIAL, a Prospective Cohort Study of Patients Undergoing Prepectoral Breast Reconstruction
The investigators conducted a prospective cohort study to assess the safety, quality of life and cosmetic sequelae of prepectoral breast reconstruction in women with breast cancer and high risk.
- Conditions
- Breast Cancer, Quality of Life, Surgery--Complications
- Trial name
- PreQ-20 (NCT04642508)
- Testing
- Prepectoral reconstruction
- Where
- Spain
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospital A Coruña
Digestion-associated Quality of Life
Radicle GI Health RAATM: A Study Assessing the Impact of Health and Wellness Products on Gastrointestinal-Related Quality of Life and Related Health Outcomes
Radicle GI Health RAA: A randomized, double-blind, placebo- controlled direct-to-consumer study assessing the impact of health and wellness products on gastrointestinal-related quality of life and related health outcomes.
- Trial name
- NCT07653776
- Testing
- Active GI Health Product 1
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Obesity, Bariatric Surgery
Mobile Application for Bariatric Surgery Patients
Introduction: One of the alternative ways, as a result of the increasing demand for health services and the inadequacy of meeting the increasing needs, is mobile health applications.
- Conditions
- Obesity, Bariatric Surgery, Quality of Life, Complication
- Trial name
- NCT05428618
- Testing
- e-BariS app group, Self-Monitoring Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Eosinophilic Esophagitis
A Non-interventional Observational Study to Assess Long-term Efficacy and Safety of Dupilumab for the Treatment of Patients (>= 12 Years) With Eosinophilic Esophagitis Under Real-world-conditions in Germany
This is a longitudinal, observational non-interventional study (NIS) designed to characterize the patient population who receives dupilumab for eosinophilic esophagitis (EoE) treatment in a real-world setting in Germany with…
- Trial name
- ProMEAL (NCT06695897)
- Testing
- Dupilumab
- Where
- 15 sites in Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sanofi
Autism Spectrum Disorder
Individualized Parent-Based Nutrition Education in Preschool Children With Autism Spectrum Disorder
Feeding difficulties, such as food selectivity and refusal to try new foods, are common among preschool children with autism spectrum disorder (ASD).
- Trial name
- NCT07884097
- Testing
- Individualized Parent-Based Nutrition Education Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Firat University
Breast Neoplasms, Alopecia
Effect of Cryotherapy in the Prevention of Madarosis Produced by Chemotherapy in Breast Cancer Patients
Chemotherapy-induced alopecia (CIA) significantly compromises body image in breast cancer patients, particularly when involving eyebrow and eyelash loss (madarosis).
- Conditions
- Breast Neoplasms, Alopecia, Madarosis, Eyebrow Diseases
- Trial name
- NCT06955702
- Testing
- cryotherapy for chemotherapy-induced madarosis
- Where
- 2 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity
Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
The goal of this action research project is to develop and implement nature- and activity-based group interventions across health care, school and leisure settings in Southern Norway.
- Conditions
- Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity, Autism, Tourette Syndrome
- Trial name
- NCT07203469
- Testing
- Universal approach, Selective approach, Outdoor therapy
- Where
- 2 sites in Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Leadless Micra Transcatheter Pacemaker, Quality of Life
Quality of Life in Patients Treated With Leadless Pacemakers
The study aims to carry out a domestic multi-center, prospective, non-randomized, non-blinded post-approval study to assess health-related QoL between Micra TPS and conventional PM implantation.
- Trial name
- NCT05958836
- Testing
- pacemaker
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital