Clinical trials: Quantification
Myocardial Infarction
Optimisation and Quantification of Contrast Enhanced Computed Tomography Myocardial Fibrosis Imaging
Detecting scarred heart muscle is important to diagnose and treat of a wide variety of heart conditions. Magnetic resonance imaging (MRI) can assess scarred heart muscle but it is time consuming, contraindicated for some patients…
- Trial name
- NCT02364687
- Testing
- Computed tomography late enhancement imaging
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Non-Alcoholic Fatty Liver Disease
Ultrasound Quantification of Liver Fat
The investigators plan a prospective study designed to evaluate the accuracy of a new ultrasound method for quantification of liver fat content.
- Trial name
- NCT04523584
- Testing
- Magnetic Resonance Imaging (MRI), Ultrasound Imaging
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Diabetic Macular Oedema
Quantification of Rising the Osmotic Pressure in Diabetic Intraretinal Fluid Accumulation (Diabetic Macular Oedema)
Diabetic macular oedema is characterized by fluid accumulation in the retinal tissue from leaking retinal vessels, the capillaries. This state can lead to severe visual loss and blindness.
- Trial name
- NCT00333671
- Testing
- Glycerol
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Parkinson Disease, Sleep
Quantitation of Glymphatic Functioning in Sleep and Meditative States
This involves development and application of magnetic resonance imaging (MRI) methods for visualizing hemodynamic and metabolic relationships in healthy volunteers with advanced meditation experience.
- Trial name
- NCT04506892
- Testing
- Meditation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pancreatic Exocrine Insufficiency
The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
- Trial name
- DETECTION (NCT05980221)
- Testing
- Metabolomics, 13C MTGT
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Prostate Cancer
Quantification of Respiratory-induced Prostate Motion
Patient anatomy and position during the course of radiation therapy can vary from those used for treatment planning; a function of patient movement, uncertainty in positioning system, and organ motion.
- Trial name
- NCT00980993
- Where
- United States
- Sponsor
- Oregon Health and Science University
Allergic Conjunctivitis
Assessment of Alcon's Ocular Image Quantification System
The purpose of this study was to evaluate ocular responses with different allergen provocation methods.
- Trial name
- NCT01282138
- Testing
- Olopatadine hydrochloride, 0.1% ophthalmic solution (Patanol), Dextran 70 0.1%, hydroxypropyl methylcellulose 0.3% (Tears Naturale II)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Alcon Research
Lymphoma, Nonneoplastic Condition
Biomarkers in Blood Samples From Patients With HIV Infection and Stage III or Stage IV Hodgkin Lymphoma Undergoing Chemotherapy
RATIONALE: Studying samples of blood in the laboratory from patients undergoing treatment with HIV infection and Hodgkin lymphoma may help doctors learn more about the effects of therapy on HIV.
- Trial name
- NCT01319526
- Testing
- DNA analysis, RNA analysis, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- AIDS Malignancy Consortium
Carotid Stenosis
Ultrasonographic Morphology Assessment of Low-grade Carotid Stenosis
Internal carotid artery (ICA) is intended to supply blood to brain. The carotid bulb located upstream of ICA origin is prone to atherosclerosis.
- Trial name
- QUAMUS (NCT05437991)
- Testing
- Independent morphological quantifications by echo-doppler using ECST method
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Depression, Anhedonia
Multimodal Differences in Effort-based Decision-Making in Depression
Major depressive disorder (MDD) is a serious condition that causes long-term symptoms such as feeling sad, losing interest in activities, and having thoughts of self-harm.
- Trial name
- BBQS (NCT06648460)
- Testing
- Effort-based Decision-Making Task
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Pulmonary Cancer
Quantification of microRNAs in Diagnosis of Pulmonary Nodules
One of the main challenges of thoracic oncology lies in earlier diagnosis of lung cancer to improve survival rate, wich is about 15% at 5 years. This poor prognosis is often linked to late diagnosis.
- Trial name
- miR-Nod (NCT03293433)
- Testing
- Blood punction
- Where
- 2 sites in France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Toulouse
Ovary Inflammation
Novel Evaluation of Aspirated Follicular Fluid
A molecular study of follicular fluid aspirated from ovarian follicles during routine in vitro fertilization treatment, after the eggs were identified and separated.
- Trial name
- NCT02999555
- Testing
- Ovum pickup
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Caffeine
Caffeine and Training Intensity Quantification
The goal of this clinical trial is to learn about the effects of caffeine on exercise physiology and the subsequent quantification of athlete training zones in trained cyclists.
- Trial name
- NCT06210984
- Testing
- Low caffeine dose, Moderate caffeine dose
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Leg Length Inequality, Cerebral Palsy
Spine Biomechanics During Gait Following Lower Extremity Treatment in Different Patient Groups
Measuring spine dynamics is a necessity in order to better understand gait deviations throughout the whole body and to evaluate treatment effects on spinal movement during gait.
- Trial name
- NCT01803243
- Testing
- Ankle foot orthosis, Shoe insole, Modified shoe with sole lift
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Children's Hospital Basel
Intermuscular Adipose Tissue Quantification
Impact of Muscle Fat Accumulation on the Genomic Profile of Skeletal Muscle in Older Adults
Subjects were asked to come to the Purdue facilities after an overnight fast on 2 different testing days for 2.5 hours each day.
- Trial name
- NCT02187965
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Purdue University
Type 1 Diabetes Mellitus
Molecular Quantification of Insulin mRNA
The objectives of this study are to: 1. quantitate the level of insulin mRNA in the while cell fraction of whole blood in selected groups of subjects, 2.
- Trial name
- NCT00324207
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
HIV-1-infection
Quantification of Antisense HIV RNA in Patients
The objective of this study is to quantify the expression levels of the HIV-1 unspliced sense transcript and of total HIV-1 antisense transcripts in PBMCs of HIV-1-infected persons, either still untreated or virologically…
- Trial name
- NCT05381844
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Coronary Artery Disease
xSPECT-based Myocardial Perfusion Scintigraphy: Consistency of Functional Values and Feasibility of Myocardial Uptake Quantitation in Patients With Suspected Coronary Artery Disease
This study is to evaluate the feasibility of myocardial Standardized Uptake Volume (SUV) assessment by means of X- (Single photon emission tomography) SPECT/Computed tomography (CT), to assess normal reference value under rest…
- Trial name
- xSPECT MPI (NCT04583787)
- Testing
- 99mTc-sestamibi myocardial perfusion SPECT, 82Rb-Chloride myocardial perfusion PET with CCTA
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Basel, Switzerland
Lateral Gluteal Depression
Analyze Previously Collected Biopsy Samples From Participants Who Completed the "SPLASH: Split-Body Randomized Clinical Trial of Poly-L-Lactic Acid for Adipogenesis and Volumization of the Hip Dell" Study
Primary Objective: use immunofluorescence (IF) on previously obtained biopsies to analyze and quantify changes in adipose tissue of subjects injected with poly-L-lactic acid (PLLA) or saline.
- Trial name
- NCT06656923
- Testing
- Biopsies
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Pressure Ulcer, Bedsore
Quantification of the Pressure Threshold Related to Tissue Injury in Bedriden Paraplegics
The aim of this study is to correlate the intensity and the duration of a mechanical strain, applied over the skin of a bedridden paraplegics, with the microvascularization parameters (oxygen saturation, blood flow and blood…
- Conditions
- Pressure Ulcer, Bedsore, Spinal Cord Injury, Paraplegia
- Trial name
- NCT02412046
- Testing
- Muscle biopsy
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Montpellier