Clinical trials: Quantification
SARS-CoV-2, SARS-CoV-2 (COVID-19) Infection
Study SARS-CoV-2-CZ-PREVAL-II - Arm of the Olomouc Region
The aim of the study is to find the proportion of people in the population of the Olomouc Region with the presence of IgG (or IgM) antibodies against the S and N antigens of the SARS-CoV-2 virus, therefore people who have already…
- Trial name
- NCT07387211
- Testing
- Blood sampling, Gargle sampling, Questionnaire completion
- Where
- Czechia
- Volunteers
- 2,484 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Parkinson Disease
neuroQWERTY: a Transparent Patient-centered Outcome Method to Quantify Parkinsonian Motor Signs for Drug Trials
The motor impairment produced by Parkinson's disease (PD) is a significant and debilitating part of the condition. Current methods to evaluate this impairment rely on subjective examinations.
- Trial name
- neuroQWERTY (NCT02522065)
- Where
- 6 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundación de investigación HM
Healthy
PET Imaging of Dopamine in Healthy Study Participants
The purpose of this study is to measure molecules on or in cells that interact with a chemical in the nervous system, called dopamine.
- Trial name
- NCT00062946
- Testing
- (18F)fallypride
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Resorption of Mandible
3D Assessment of Mandibular Bone Loss Via STL Superimposition After Complete Denture Occlusal Adjustment
STL registration-based superimposition is an advanced technique for assessing mandibular bone resorption in removable complete denture (RCD) patients.
- Trial name
- NCT06562972
- Testing
- Occlusal equilibration of complete denture using articulating paper, Occlusal equilibration of complete denture using occulosense
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Badr University
Celiac Disease
Quantification of Gluten Peptides in Feces
Treatment for celiac disease (CD) is a lifelong strict gluten-free diet (GFD). Patients should be followed-up with dietary interviews and serologic tests for CD markers to ensure adherence to the diet.
- Trial name
- DELIAC (NCT02711397)
- Testing
- Observational study
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Biomedal S.L.
Disease
Quantification of Microbiota in Health and Diseases
Microbiota consists of trillions of microorganisms located in all the biological cavity. The relationships between individual health status and microbiota are based on a sort of "mutual cooperation." The balance of the microbiota…
- Trial name
- qMHD (NCT03388424)
- Testing
- quantification of microbiota
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Brain Connectivity
Resting State Changes Following Theta Burst Stimulation
Transcranial magnetic stimulation (TMS) is increasingly being applied to effectively treat mental illness, however efforts to quantify the effects of TMS on the network architecture of the brain have largely been limited in scope…
- Trial name
- NCT05322239
- Testing
- Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nicholas Balderston, PhD
Steatosis of Liver
Ultrasound Index Fat Fraction
The objective is to compare the ultrasound index fat fraction (FAT PLUS), derived from several ultrasound biomarkers, with the gold-standard imaging exam for liver fat content evaluation (MRI-PDFF) in patients to quantify the…
- Trial name
- FAT-PLUS (NCT06373796)
- Testing
- Echographic scan
- Where
- France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- SuperSonic Imagine
Liver Fibroses, Hepatic Steatosis
Methods to Detect Liver Fibrosis
The goal of this study is to learn more about liver fibrosis and methods to detect it. We will evaluate and compare multiple MRI based measures of liver fibrosis in subjects with and without liver disease.
- Trial name
- NCT03027700
- Testing
- MRI
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Breast Milk Collection
Analysis of Lipids in Human Milk At Different Gestational Ages
Various studies have shown that the milk of a preterm infant differs from that of a term infant in the composition of micronutrients, vitamins, macronutrients, carbohydrates and proteins.
- Trial name
- NCT05989009
- Testing
- Breastfeeding
- Where
- 2 sites in Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Breast Cancer
Breast Study Investigating a New Light Technique to Monitor Changes in Breast Tissue Density
The purpose of this study is to test the ability of a technique called Transillumination Breast Spectroscopy (TIBS) to monitor an individual's breast density changes over time.
- Trial name
- NCT00188760
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Rheumatoid Arthritis
Quantification of GADD34 Expression in RA
GADD34 is an inducible cofactor of protein phosphatase 1, which has an important role in the Unfolded Protein Response (UPR). UPR is a cellular response to ER stress which is implicated in several autoimmune diseases.
- Trial name
- GADD34-RA (NCT02401165)
- Testing
- Blood test
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Liver Cirrhosis
Clinical Trial Multi-analyte Blood Test
This is a clinical trial designed to evaluate the performance of a multi-analyte blood test alone to ultrasound alone for the detection of HCC within a population that is at high risk for HCC due to liver cirrhosis.
- Trial name
- CLiMB (NCT03694600)
- Testing
- Multi-analyte blood Test
- Where
- 38 sites in United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Helio Genomics
Irritable Bowel Syndrome, Digestive System Diseases
Abnormal Expression Proteins, Mitochondrial DNA and miRNA of Irritable Bowel Syndrome
In the investigators study, the investigators will focus on the screening of the related proteins and miRNA to IBS in order to reveal the possible clues or molecular mechanism for this disorder.
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Gastrointestinal Diseases, Intestinal Diseases
- Trial name
- IBS (NCT01028898)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Gaucher
MR Spectroscopy and Disease Severity Score for Gaucher in Pediatric Population
The bone status in Gaucher disease is very difficult to monitor precisely in children. This is a major problem because lack of optimal treatment, especially enzyme replacement, may cause irreversible severe bone damage that will…
- Trial name
- MRS in Gaucher (NCT01397435)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Long COVID
Health-related Quality of Life and Long COVID
Background: Long COVID is estimated to affect 1.7 million people in the UK. One way of assessing the impact of long COVID is to measure quality-of-life through a standard questionnaire, which can then be used to understand the…
- Trial name
- OpenPROMPT (NCT05552612)
- Where
- United Kingdom
- Volunteers
- 7,574 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Smoking, Cigarette
Establishment of a Method for Extraction and Quantification of Gingival Tissue Nicotine y
establishment of a method for extraction and quantification of gingival tissue nicotine in relation to conventional tobacco biomarkers: a pilot study
- Trial name
- NCT05736250
- Testing
- biopsie
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Liege
Pectus Excavatum
Three-dimensional Optical Surface Imaging as a Diagnostic Tool in Pectus Excavatum
Pectus excavatum (PE) is the most common anterior chest wall deformity. Currently, a chest radiography (CR) or Computed Tomography (CT) scan is acquired to determine and objectify pectus severity using the Haller Index.
- Trial name
- 3D PECTUS (NCT03926078)
- Testing
- 3D optical surface image, Chest radiography, CT scan
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Diabetes, Obesity
Multi-Tracer PET Quantitation of Skeletal Muscle Insulin Resistance in Type 2 Diabetes Mellitus
The purpose of this research is to use a recently developed triple-tracer positron emission tomography (PET) method to study skeletal muscle insulin resistance.
- Trial name
- NCT00222781
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh