Clinical trials: RANDOMIZED
Hamstring Flexibility
Effects of Combining PNF With NMES in Young Basketball Players
Hamstring muscle injuries are common in basketball and result in long periods of inactivity. This study aims to compare two different stretching programs to assess their effects on hamstring flexibility and, secondarily, on…
- Trial name
- PNF+NMES (NCT06648356)
- Testing
- Neuromuscular electrical stimulation (NMES), Contract-Relax PNF (crPNF)
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Renal Insufficiency, Chronic, Graft Occlusion, Vascular
External Ionizing Radiation to Prevent Restenosis on Haemodialysis Vascular Access
Although ionizing radiations have been proposed for the prevention of intimal hyperplasia in coronary and peripheral arteries, information is lacking on how irradiation may prevent neointimal smooth-muscle cell proliferation and…
- Conditions
- Renal Insufficiency, Chronic, Graft Occlusion, Vascular, Thrombosis, Intimal Hyperplasia
- Trial name
- RASTA (NCT00379366)
- Testing
- External ionizing radiations
- Where
- 5 sites in France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Bordeaux
Aging
Effects of Monarda Didyma Extract Supplementation on Biological Ageing
This research aims to explore the potential benefits of supplementation of a natural ingredient, the Monarda didyma extract, to reduce / delay the biological aging of a susceptible population, thus contributing to two relevant…
- Trial name
- EMODISU (NCT05399966)
- Testing
- Monarda Didyma extract
- Where
- Italy
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Sofia Pavanello
Perinatal Loss, Grief
Digital Perinatal Bereavement Support Program for Women After Pregnancy Loss
This study aims to evaluate the effectiveness of a digital perinatal bereavement support program designed for women who have experienced pregnancy loss.
- Conditions
- Perinatal Loss, Grief, Depression Anxiety Disorder
- Trial name
- DPBSP (NCT07545551)
- Testing
- Supportive Care
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gazi University
Metastatic Solid Tumors of Metastatic Disease
Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain
The purpose of the study is to compare the outcome of patients who receive standard treatment versus those who receive preventative radiation and then standard treatment.
- Trial name
- NCT03523351
- Testing
- Radiation Therapy, Systemic Therapy
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Obesity, Overweight
Nutrition and Soccer for Pediatric Overweight and Obesity
This study will examine whether two months of youth soccer, combined with a single brief behavioral/nutritional intervention, can reduce BMI in 5th grade overweight or obese females.
- Trial name
- NCT00365651
- Testing
- Youth Soccer
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Leach Chiropractic Clinic
Type 1 Diabetes Mellitus
Clinical Trial Evaluating Technosphere® Insulin Versus Insulin Aspart in Subjects With Type 1 Diabetes Mellitus Over a 24-week Treatment Period
Open-label, randomized, forced-titration clinical trial evaluating the efficacy and safety of TI Inhalation Power in combination with a basal insulin versus insulin aspart in combination with a basal insulin
- Trial name
- NCT01445951
- Testing
- Technosphere® Insulin with MedTone C Inhaler, Technosphere ®Insulin with Gen2 Inhaler, Insulin Aspart in combination with a basal insulin
- Where
- 90 sites in United States, Brazil and 2 more
- Volunteers
- 518 people
- Sponsor
- Mannkind Corporation
Percutaneous Endoscopic Gastrostomy (PEG)
Additional Benefit of Thoracic Impedance Monitoring (TIM) for Propofol-sedation Monitoring During PEG Placement
The present study is a randomized, prospective, single-blinded study. A total of 172 patients presenting for percoutaneous endoscopic gastrostomy (PEG) under sedation will be included according to the statistical sample size…
- Trial name
- TIMPEG (NCT04202029)
- Testing
- thoracic impedance monitoring, pulseoxymetry, non-invasive blood preassure monitoring
- Where
- Germany
- Volunteers
- 173 people
- Sponsor
- Georg Dultz
Healthy Male Volunteer
The Pharmacokinetic Interaction Between CKD-501 and Sulfonylurea
To assess the pharmacokinetic Interaction between CKD-501 and sulfonylurea (Glimepiride) in healthy male subjects.
- Trial name
- CKD-501 DDI (NCT01133431)
- Testing
- CKD-501 0.5 mg tablet, Glimepiride 4 mg tablet
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy Volunteers
Trial on Single/Multiple Ascending Doses for Safety, PK and PD for CBP-0276 in Healthy Subjects
A double-blind, randomized, placebo-controlled, single and multiple ascending dose study with food effect to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of CBP-0276.
- Trial name
- CBP276SADMAD (NCT07708831)
- Testing
- CBP-0276 Acetate
- Where
- 2 sites in Mexico
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Clarent Biopharma, Inc.
Overweight and Obesity, Healthy
The Impact of High-Fat Ketogenic Diet and Low-Fat Diet in Women Body Weight
The aim of this study is investigated the effect of high fat Ketogenic Diet (HFKD) in weight reduction compared to the low-fat diet (LFD) among Saudi overweight and obese women.
- Trial name
- NCT05811702
- Testing
- A randomized acute controlled trial of twenty-eight healthy overweight or obese women
- Where
- Saudi Arabia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- King Faisal University
Overactive Bladder
MIrabegron With oveRACtive bLadder Symptoms in mEn
The proportion of male patients who participated in the phase III study of mirabegron was about 28% and the data on the efficacy and safety of mirabegron in Korean male OAB patients have limits.
- Trial name
- NCT02361502
- Testing
- mirabegron
- Where
- 15 sites in South Korea
- Volunteers
- 462 people
- Sponsor
- Seoul National University Hospital
Spinal Muscular Atrophy, Neuromuscular Diseases
A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy
This trial will study the efficacy and safety of taldefgrobep alfa as an adjunctive therapy for participants who are already taking a stable dose of nusinersen and/or risdiplam and/or have a history of onasemnogene abeparvovec…
- Conditions
- Spinal Muscular Atrophy, Neuromuscular Diseases, SMA
- Trial name
- RESILIENT (NCT05337553)
- Testing
- taldefgrobep alfa
- Where
- 53 sites in United States, Belgium and 7 more
- Volunteers
- 269 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Transient Tachypnea Newborn, Cesarean Delivery Affecting Fetus
Misoprostol Before Elective Caesarean Section for Decreasing the Neonatal Respiratory Morbidity
Neonatal respiratory distress may occur in either term or preterm newborns with a higher relative risk in preterm, and whether born vaginally or through caesarean section, but in a higher percentage after elective caesarean…
- Trial name
- NCT03031353
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Ain Shams University
Hemorrhoids
EnSeal Device Versus Ferguson Technique in Hemorrhoidectomy
This study will compare hemorrhoid surgery by comparing a sutureless heating device with the old standard hemorrhoid surgery. Patients will be followed closely for wound healing and satisfaction.
- Trial name
- NCT00853853
- Testing
- EnSeal Device, Ferguson Hemorrhoidectomy technique
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Steven Schechter, M.D.
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Parkinson's Disease
Tango for Treatment of Motor and Non-motor Manifestations in Parkinson's Disease.
Parkinson's disease involves many motor difficulties as well as non-motor ones. Recent research has strongly suggested that exercise is very important for Parkinson's disease.
- Trial name
- NCT01573260
- Testing
- Argentinean Tango classes, Simple pamphlet about the exercise in PD
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Colon Cancer, Colorectal Cancer
Yttrium Microspheres With Cetuximab Plus Irinotecan for Patients With Advanced Colorectal Cancer Mets to Liver
The goal of this clinical research study is to find out what effects radioactive particles, SIR-spheres, have when injected into the liver, followed by systemic chemotherapy with a combination of cetuximab and irinotecan compared…
- Trial name
- NCT00766220
- Testing
- SIR-spheres Agent Administration, Cetuximab, Irinotecan
- Sponsor
- M.D. Anderson Cancer Center
Impaired Fasting Glucose, Newly-diagnosed Type 2 Diabetes
A Randomized Trial to Assess the Efficacy and Safety of GO2KA1(Chitosan Oligosaccharide)on Blood Glucose Control
The effects of chitosan on blood glucose levels have been contradicting. Hypoglycemic effects of high molecular weight chitosan are related to diabetic models with hypoinsulinemia but have shown little effect on the blood glucose…
- Trial name
- NCT01496820
- Testing
- GO2KA1
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Bladder Cancer
A Study of Intravesical Qapzola (Apaziquone) as a Surgical Adjuvant in Participants Undergoing Transurethral Resection of Bladder Tumor (TURBT)
This is a randomized, multicenter, two-arm, double-blind, placebo-controlled study of Qapzola in participants with low- to intermediate-risk non-muscle invasive bladder cancer (NMIBC), assessed according to the 2016 American…
- Trial name
- NCT03224182
- Testing
- Qapzola
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Spectrum Pharmaceuticals, Inc
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