Clinical trials: RHINOPLASTY
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Rhinoplasty, AI (Artificial Intelligence)
AI in Assessing Aesthetic Outcomes in Rhinoplasty
This study aims to thoroughly assess the predictive accuracy of artificial intelligence-based nasal outcome simulations by comparing AI-generated preoperative predictions with objective postoperative nasal morphology using…
- Trial name
- NCT07580573
- Testing
- AI
- Volunteers
- 20 people
- Sponsor
- Assiut University
Nasal Obstruction
Medical Rhinoplasty: Evaluation of the Efficacy of Hyaluronic Acid in the Treatment of Internal Nasal Valves.
Nasal obstruction is a possible complication of rhinoplasty surgery. Several causes can explain it: deviation of the nasal septum, appearance of mucosal flanges inside the nasal cavity, but also collapse of the internal valve by…
- Trial name
- Rhinomedifon (NCT05134831)
- Testing
- Rhinomanometry
- Sponsor
- Hospices Civils de Lyon
Rhinoplasty, MeSh E02.218.755
Comparative Evaluation of Cocaine and Adrenaline as Topical Vasonconstrictor Agents in Cosmetic Rhinoplasty
This study aims to compare two vasoconstrictive agents topically applied in cosmetic rhinoplasty: cocaine HCl 5% and adrenaline 1:1000. Blood loss during surgery as well as systemic effect of the studied agents are evaluated.
- Trial name
- NCT02381041
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Clínica Fernández
Postoperative Sleep Disturbances
Comparison Of The Effects Of Melatonin Premedication And Ketamine On Postoperative Sleep Quality İn Rhinoplasty
Background Postoperative sleep disorders are common complications of surgery and anesthesia that prolong morbidity and hospital stay. Various methods are being explored to prevent and treat these issues.
- Trial name
- NCT06898463
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine), Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Konya City Hospital
Effect of Postoperative Topical St. John's Wort Oil (Hypericum Perforatum) on Periorbital Edema and Ecchymosis Following Rhinoplasty
THE EFFECT OF ST. JOHN'S WORT OİL APPLİCATİON ON PERIORBITAL EDEMA AND ECCHYMOSİS AFTER RHİNOPLASTY
Rhinoplasty is one of the most frequently performed procedures in aesthetic and reconstructive surgery, with steadily increasing demand worldwide.
- Trial name
- NCT07448051
- Testing
- Topical St. John's Wort oil application
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Rhinoplasty Surgery
Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology.
- Trial name
- Effects of Dex (NCT06138574)
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Rhinoplasty, Nasal Surgery
Lateral Crural Steal With Columellar Strut Graft in Primary Open Rhinoplasty
The goal of this clinical trial is to assess the effect of Lateral crural steal with Columellar strut graft done in Primary Open Rhinoplasty and its long-term sustainability on nasal tip projection and nasal tip rotation.
- Conditions
- Rhinoplasty, Nasal Surgery, Aesthetic Outcomes
- Trial name
- LCS/CS (NCT07317947)
- Testing
- Lateral crural steal with columellar strut graft in Primary Open Rhinoplasty
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Kafrelsheikh University
Remimazolam, Emergence Delirium
Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty
The aim of this research is to confirm the effectiveness of remimazolam in preventing delirium during recovery from anesthesia in adult patients who have undergone one of the rhinological surgeries (septoplasty, rhinoseptoplasty…
- Conditions
- Remimazolam, Emergence Delirium, Rhinoplasty
- Trial name
- NCT06398275
- Testing
- Remimazolam 20 MG Injection [Byfavo], NaCl 0.9%
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University Hospital of Split
Nasal Obstruction, Nasal Surgical Procedures
Antibiotic Prophylaxis in Rhinoplasty
This study compares the efficacy of a single intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides), alone versus both intra-operative (intravenous) dose of…
- Trial name
- NCT04194216
- Testing
- Intra-operative single intravenous(iv) dose of "cephalexin" 2 g or "clindamycin" 900 mg., Intra-operative single dose (iv) of "cephalexin" 2 g or "clindamycin" 900 mg and postoperative oral dose of "cephalexin" 250mg (every 4 hours) or "clindamycin" 150mg(every 6 hours) for 3 days
- Where
- United States
- Volunteers
- 864 people
- Sponsor
- Stanford University
Head and Neck Surgery, Plastic Surgery
Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty
Septorhinoplasty is generally a prolonged surgical procedure that frequently involves osteotomy, which may lead to increased intraoperative remifentanil requirements.
- Conditions
- Head and Neck Surgery, Plastic Surgery, Rhinoplasty, Pain
- Trial name
- PRISM (NCT07233538)
- Testing
- Maxillary block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Outpatient Rhinoplasty
Facial Block for Outpatient Rhinoplasty Analgesia
A bilateral facial block (infraorbital and infratrochlear) will be performed immediately after intubation in patients undergoing outpatient rhinoplasty with 2.5% levobupivacaine (intervention group) or saline as control.
- Trial name
- FABLORA (NCT01872728)
- Testing
- Bilateral facial block after general anesthesia before surgery
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Rhinoplasty
Comparison of Septal Advancement Flap and Columellar Strut Effect on Nasal Tip
The aim of the study to compare and evaluate the effect of septal advancement flap in preserving and reshaping the nasal tip with columellar strut graft
- Trial name
- NCT06370455
- Testing
- comparison of septal advancement flap effect on nasal tip in primary rhinoplasty to columellar strut technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Wound Healing
Arnica Montana and Bromelain in Rhinoplasty
The purpose of this study is to assess the perioperative use of Arnica Montana and the combined use of Arnica Montana and Bromelain in aiding the body's wound healing functions during the postoperative period after rhinoplasty.
- Trial name
- NCT03586232
- Testing
- Arnica Montana, Bromelain
- Where
- United States
- Sponsor
- Boston Medical Center
Pain, Postoperative
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
The purpose of this study is to find out which pain medication is more effective in reducing pain after nose surgery (rhinoplasty).
- Trial name
- NCT07689162
- Testing
- Standard Bupivacaine, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Washington University School of Medicine
Ecchymosis; Eyelid, Edema
Topical Tranexamic Acid Application in Rhinoplasty
The aim of this study is to examine the effectiveness of topical Tranexamic acid application in overcoming periorbital ecchymosis and edema after rhinoplasty, which are common and do not have a standard treatment.
- Conditions
- Ecchymosis; Eyelid, Edema, Rhinoplasty
- Trial name
- NCT05326139
- Testing
- Tranexamic acid, Isotonic saline
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Baskent University
Rhinoplasty, Edema
Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre
This single-centre, randomized, double-blind, sham-controlled clinical trial evaluates whether preoperative photobiomodulation (PBM) with red and infrared light can reduce early postoperative periorbital edema in patients…
- Trial name
- NCT07033039
- Testing
- Photobiomodulation, Simulation of Photobiomodulation, Standard treatment protocol
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Ecchymosis
The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery
Arnica montana is a homeopathic drug that is made in accordance with the official methods of the Homeopathic Pharmacopoeia of the United States (HPUS) and is commonly used by cosmetic surgeons throughout the world, although there…
- Trial name
- NCT01164644
- Testing
- Arnica montana
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wisconsin, Madison
Rhinoplasty Techniques
Spreader Graft and Lateral Crural Overlay Technique in Rhinoplasty
Most of the studies performed to compare the present techniques of rhinoplasty have been based on the clinical examination and change of postoperative complaints that cannot be very precise in evaluating the advantages of one…
- Trial name
- NCT01852643
- Testing
- Spreader graft, Lateral crural overlay
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences
Rhinoplasty, Nursing Education
Education's Impact on Involuntary Thoughts and Healing in Rhinoplasty Patients
With planned trainings prepared by taking into account the needs of patients and given by nurses, levels of anxiety and involuntary thoughts can be reduced and the quality of service and recovery can be increased.
- Trial name
- NCT06771297
- Testing
- nursing education
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk Training and Research Hospital