Clinical trials: Radiation Protection
Radiation Protection
Study to Evaluate the Clinical Utility of Radiation Exposure Reduction: Multi-site Rampart Guardian Peripheral Trial
Study to Evaluate the Clinical Utility of Radiation Exposure Reduction (SECURE): Multi-site Rampart Guardian Peripheral Trial
- Trial name
- SECURE (NCT07467720)
- Testing
- Rampart IC System
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Baylor Research Institute
Kidney Failure, Acute, Myopathy; Drugs
The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)
The study aims to improve the safety of the electroporation ablation (PFA) procedure by using muscle relaxants to reduce skeletal muscle damage during the procedure.
- Conditions
- Kidney Failure, Acute, Myopathy; Drugs, Heart Arrhythmia, Succinylcholine Sensitivity
- Trial name
- NCT06707532
- Testing
- Propofol, Rocuronium
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Solar Skin Damage
Flavanols and Skin Photo Protection: a Clinical Trial
As flavanols have antioxidants, anti-inflammatory and anti-DNA damaging effects and may increase microcirculation in skin, the purpose of the study is to investigate the chronic effect of flavanol-rich chocolate as an effective…
- Trial name
- CHOCOPO (NCT01444625)
- Testing
- Flavanol-rich chocolate, Flavanol-free chocolate
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Laval University
Esophageal, Toxicity
MnSOD (Esophageal Protectant) to Prevent Esophagitis During Radiation/Chemotherapy Treatment for Non-Small Cell Lung Cancer (NSCLC)
This is a Phase I-II study evaluating the feasibility, safety, and efficacy of swallowed MnSOD plasmid/liposome (PL) transgene given as protection against radiation-induced esophagitis during concurrent paclitaxel and carboplatin…
- Trial name
- MnSOD (NCT00618917)
- Testing
- Manganese Superoxide Dismutase Plasmid Liposome, carboplatin, paclitaxel
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Joel Greenberger
Melanoma, UV Ray Skin Damage
A Sunscreen Based on Bioadhesive Nanoparticles
The initial focus of the study will be on safety, sun protection factor (SPF) characterization, and substantivity (duration of protection) studies.
- Trial name
- NCT02668536
- Testing
- Standard Sunscreen, BNP
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Yale University
Radiation Induced Oral Mucositis
A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer
The purpose of the phase 2, GT-201 clinical study is to determine if GC4419 administered prior to intensity-modulated radiation therapy (IMRT) reduces the incidence, duration, and severity of radiation induced oral mucositis in…
- Trial name
- NCT02508389
- Testing
- Low Dose GC4419: 30mg/day, High Dose GC4419: 90mg/day, Intensity-Modulated Radiation Therapy
- Where
- 64 sites in United States, Canada and 1 more
- Volunteers
- 223 people
- Sponsor
- Galera Therapeutics, Inc.
Radiodermatitis, Injury, Radiation
Study Using Spray Skin Protector Versus Conventional Treatment to Prevent Acute Radiodermatitis.
This is a randomized, open-label, single-institution trial designed to evaluate the effectiveness of a spray skin protector in preventing moist desquamation caused by radiotherapy treatment.
- Trial name
- NCT04067310
- Testing
- Spray skin protector, moisturizer Dnativ Revita derm
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Radiation Exposure
Clinical Evaluation of a Novel Textile Radiation Protection Device
This study will use procedure-specific dosimetry to evaluate whether Texray's novel woven radiation protection fabric (HeadPeace and MindPeace) reduces occupational radiation dose to the head and thyroid of interventional…
- Trial name
- NCT07768605
- Testing
- Standard PPE, Texray PPE
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Radiation Exposure, Radiation Exposure to Operator
The Radiation ProtEction for Dose RedUction in the Cardiac CathEter Lab Study: The REDUCE Trial
Doctors and nurses who perform heart procedures using X-ray guidance are exposed to radiation, which can be harmful over time. This exposure increases the risk of certain health problems, including cancers, eye damage…
- Conditions
- Radiation Exposure, Radiation Exposure to Operator, Radiation Injuries, Radiation Safety
- Trial name
- REDUCE (NCT06875583)
- Testing
- Radiation
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Healthy Volunteer Study
Phase 1 BIO 300 Oral Suspension
This is a two-part study of BIO 300 Oral Suspension in healthy male and female volunteers. The first part is a multiple ascending dose (MAD) study to test the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of the drug…
- Trial name
- NCT06741345
- Testing
- BIO 300 Oral Suspension
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Humanetics Corporation
Radiation Dermatitis
Skin Protection During Radiotherapy in Patients With Breast Cancer
Radiotherapy may cause severe skin changes that significantly interfere with the patient's quality of life and may reduce radiotherapy effectiveness.
- Trial name
- EVOSKIN (NCT02334345)
- Testing
- Evoskin, Trixiera
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Limoges
Radiation Exposure
Comparison Of Effective Radiation Shielding Between Rampart IC, M1128 Shield vs Conventional Apron And Shields In Clinical Interventional Procedures
Previous studies have documented that orthopedic injuries and musculoskeletal pain are a likely result of wearing heavy leaded aprons.
- Trial name
- RAMPART (NCT05347290)
- Testing
- Rampart IC, M1128, Lead Apron and Ancillary Shield, Rampart IC, M1128 and Lead Apron
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Lung Cancer
Combination Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Specialized radiation therapy delivers a high dose of radiation directly to the tumor which may kill more…
- Trial name
- NCT00004253
- Testing
- carboplatin, paclitaxel, radiation therapy
- Where
- 2 sites in United States
- Sponsor
- Baptist Health South Florida
Radiation Protection
Enhancement and Restoring of Low Dose Abdominal CT Images
Through the rapid growth of multislice Computer Tomography (CT) imaging, radiation protection has become a major issue in the radiological community.
- Trial name
- NCT01059032
- Testing
- Using a 3 dimentional post processing filter
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lars Borgen
Occupational Radiation Exposure in Interventional Cardiology
Zero-cost Radiation Protection Method to Reduce Radiation Exposure of Interventional Cardiologists During Transradial Percutaneous Coronary Procedures (FREEPADRAD Trial)
Ionising radiation is a recognised occupational hazard in interventional cardiology. This prospective, randomised trial aims to evaluate the effectiveness of additional radiation protection by existing devices but with a…
- Trial name
- FREEPADRAD (NCT06931171)
- Testing
- Patient-Applied Pelvic Lead Shielding
- Where
- 2 sites in Greece
- Volunteers
- 500 people
- Sponsor
- National and Kapodistrian University of Athens
Limited Information on Dental Radiography in Egypt
Attitude of Dentists About Radiography, Radiographic Equipment and Radiation Protection in Egypt
A Survey for Attitude and Awareness about radiography, radiographic equipment and radiation protection among dentists in Egypt
- Trial name
- NCT03938519
- Volunteers
- 900 people
- Sponsor
- Cairo University
Radiation Exposure
ATTENUATE (rAdpad proTecTion drapE iN redUcing rAdiaTion Exposure) Trial
The purpose of this study is to examine the impact of the RADPAD in proximal operators in a contemporary cardiac catheterization laboratory (CCL), during diagnostic, coronary and structural cardiac catheterization procedures, in…
- Trial name
- NCT06233578
- Testing
- RADPAD
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Prostate Cancer
Protection of Rectum From High Radiation Doses
The purpose of this study is to evaluate the usefulness of diluted DuraSeal product as a spacer between prostate and rectum in prostate cancer low dose brachytherapy.
- Trial name
- NCT01601691
- Testing
- DuraSeal
- Where
- Finland
- Volunteers
- 10 people
- Sponsor
- University of Oulu
Peripheral Arterial Disease, Peripheral Artery Disease
Digital Variance Angiography in Diagnostic Angiographies for Effective Radiation Dose Reduction
Digital Variance Angiography (DVA) is a new tool in medical imaging with proven image quality reserve. The previously observed quality reserve of Digital Variance Angiography (DVA) in lower extremity angiographies, allowed to…
- Conditions
- Peripheral Arterial Disease, Peripheral Artery Disease, Femoral Artery Stenosis, Femoral Artery Occlusion
- Trial name
- NCT04343196
- Testing
- Diagnostic Angiography (DSA or DVA based on randomization result)
- Where
- Hungary
- Volunteers
- 114 people
- Sponsor
- Kinepict Health Ltd.
Exposure of Member of Staff to Medical Diagnostic X-Ray
EffectivenesS of Additional X-ray PRotection dEviceS in Reducing Scattered Radiation in Radial interventiOn
This study evaluates the radiation exposure of scattered radiation for the interventionalist during coronary angiography using different X-ray protection materials, namely, an X-ray Screen without additional X-ray protection, an…
- Trial name
- ESPRESSO (NCT03634657)
- Testing
- Plain X-ray protection shield, Protection shield & X-ray protective strips, Protection shield & protective strips & patient cut-outs
- Where
- Germany
- Volunteers
- 700 people
- Sponsor
- Tommaso Gori