Clinical trials: Radiation-induced Esophagitis
Radiation Toxicity, Esophagitis
Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis
Purpose：To observe and evaluate the clinical efficacy and safety of deep-sea fish oil in preventing acute radiation-induced esophagitis (ARIE).
- Conditions
- Radiation Toxicity, Esophagitis, Esophageal Cancer
- Trial name
- NCT06392971
- Testing
- Deep-sea fish oil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Chengdu Medical College
Radiation-induced Esophagitis
Spirulina Derivative for Radiation Esophagitis
To evaluate the efficacy and safety of a Spirulina-derived product in preventing and treating radiation-induced esophagitis in esophageal cancer patients undergoing intensity-modulated radiotherapy (IMRT).
- Trial name
- NCT07324018
- Testing
- Hydrogel of spirulina-derived exosomes., Radiotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- West China Hospital
Radiation Esophagitis, Locally Advanced Lung Carcinoma
Esomeprazole and Radiation Induced Esophagitis
Thoracic radiation therapy combined with chemotherapy (with or without immunotherapy) is the cornerstone of management in patients with locally advanced non-small cell lung cancer (NSCLC).
- Trial name
- EERENs (NCT06120803)
- Testing
- Esomeprazole 40 mg
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Rush University Medical Center
Oral Cavity Cancer, Head and Neck Cancers - Tonsils
Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis.
- Conditions
- Oral Cavity Cancer, Head and Neck Cancers - Tonsils, Esophageal Cancer, Laryngeal Cancer
- Trial name
- NCT05369234
- Testing
- 100% Aloe Vera Juice, Magic Mouthwash, Salt and Baking soda rinse
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Covenant Health Cancer Center
Dysphagia, Lung Cancer
Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer
RATIONALE: Manuka honey may prevent or reduce esophagitis-related pain caused by chemotherapy and radiation therapy. It is not yet known whether Manuka honey is more effective than standard care in preventing pain.
- Conditions
- Dysphagia, Lung Cancer, Pain, Esophagitis
- Trial name
- NCT01262560
- Testing
- Manuka honey in liquid form, Manuka honey in lozenge form, Standard supportive care
- Where
- 59 sites in United States
- Volunteers
- 163 people
- Sponsor
- Radiation Therapy Oncology Group
Esophageal Carcinoma, Hypopharyngeal Carcinoma
Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy
This randomized pilot clinical trial studies the effects of taking doxepin hydrochloride as compared to placebo (inactive drug) in treating esophageal pain in patients with cancer located in the chest area receiving radiation…
- Conditions
- Esophageal Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Carcinoma, Lymphoma
- Trial name
- NCT02062632
- Testing
- Doxepin Hydrochloride, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Radiation-induced Oesophagitis
Tepilta® Versus Oxetacaine, Antacids and Placebo
This is a randomised, double-blind, placebo-controlled, therapeutic confirmatory multicentre trial with 4 parallel treatment groups.
- Trial name
- NCT01336530
- Testing
- oxetacaine, aluminium and magnesium hydroxide, oxetacaine, magnesium and aluminium hydroxide
- Where
- 32 sites in Austria, Germany
- Volunteers
- 40 people
- Sponsor
- MEDA Pharma GmbH & Co. KG