Clinical trials: Radical Pelvic Surgery
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Radiation Therapy With or Without Chemotherapy in Patients With Stage I-IIA Cervical Cancer Who Previously Underwent Surgery
This randomized phase III trial studies radiation therapy with chemotherapy to see how well they work compared to radiation therapy alone in treating patients with stage I-IIA cervical cancer who previously underwent surgery.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Stage I Cervical Cancer AJCC v6 and v7
- Trial name
- NCT01101451
- Testing
- Cisplatin, External Beam Radiation Therapy, Intensity-Modulated Radiation Therapy
- Where
- 719 sites in United States, Japan and 1 more
- Volunteers
- 340 people
- Sponsor
- GOG Foundation
Prostate Neoplasm, Prostatectomy
Efficacy of Extracorporeal Biofeedback Device for Post-prostatectomy Incontinence
To evaluate the efficacy of postoperative pelvic floor muscle training using personalized extracorporeal biofeedback device among patients with post-prostatectomy incontinence
- Conditions
- Prostate Neoplasm, Prostatectomy, Surgical Procedures, Robotic, Urinary Incontinence
- Trial name
- NCT02485665
- Testing
- Extracorporeal biofeedback device (Any Kegel)
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Urological Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Urological Surgeries
Study name：A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Urological Surgeries； Study purpose：This clinical trial is a real-world study to evaluate the clinical…
- Trial name
- SPiM-RWS-URO (NCT06181942)
- Testing
- SP
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Uterine Cervical Neoplasms, Laparoscopic Surgical Procedures
2D Versus 3D Radical Laparoscopic Hysterectomy for Cervical Cancer: a Prospective Randomized Trial
The aim of this prospective randomized pilot study is to verify if the operative time of a Radical abdominal hysterectomy (LRH) with pelvic lymphadenectomy for early stage cervical cancer (FIGO stages IA2-IB1-IIA<2cm) and for…
- Trial name
- NCT02320578
- Testing
- 3D Laparoscopy, Standard Laparoscopy
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Catholic University of the Sacred Heart
Prostate Cancer
PSMA-Guided Surgery and Tissue-Resident T-Cell Profiling in Node-Positive Prostate Cancer
TACTIC-P is a single-center, prospective, single-arm study in 12 men with biopsy-proven prostate cancer and pelvic lymph-node uptake on preoperative PSMA PET, without bone or visceral metastases, who are scheduled for…
- Trial name
- TACTIC-P (NCT07879820)
- Testing
- PSMA-Radioguided Robot-Assisted Radical Prostatectomy With Extended Pelvic Lymph-Node Dissection
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Niguarda Hospital
Bladder Cancer
Robotic-Assisted Laparoscopic Extended Pelvic Lymph Node Dissection for Transitional Cell Carcinoma of the Bladder
The goal of this clinical research study is to evaluate how many lymph nodes are left behind after robotic-assisted removal and are then found after a wider incision is made, in patients who are having their bladder removed for…
- Trial name
- NCT00963859
- Testing
- Robotic-assisted laparoscopic surgery
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Urothelial Carcinoma
A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract
The purpose of this study is to find out whether the study drug, enfortumab vedotin, is an effective and safe treatment for people who have urothelial carcinoma of the upper urinary tract.
- Trial name
- NCT05868265
- Testing
- Enfortumab Vedotin, Radical surgery
- Where
- 8 sites in United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gynecological Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries(SPiM-RWS-GYN)
Study name：A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries Study purpose：This clinical trial is a real-world study to evaluate the clinical…
- Trial name
- NCT06082011
- Testing
- da Vinci SP Surgical System
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Prostate Cancer, Lymphocele After Surgical Procedure
Effect of Peritoneal Fixation on Lymphocele Formation
The PerFix Trial aims to compare the use of peritoneal fixation technique to standard of care (no fixation) during robot-assisted radical prostatectomy with extended pelvic lymph node dissection (RARP + eLND) for the prevention…
- Trial name
- PerFix (NCT04853095)
- Testing
- Peritoneal fixation (PerFix), Standard of care
- Where
- Czechia
- Volunteers
- 260 people
- Sponsor
- University Hospital Olomouc
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer
This clinical trial studies the physical function and quality-of-life before and after surgery in patients with stage I cervical cancer.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Lymphedema
- Trial name
- NCT01649089
- Testing
- Conization, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 185 sites in United States, Canada and 1 more
- Volunteers
- 224 people
- Sponsor
- GOG Foundation
Prostate Cancer, Prostate Ectomy
Effects of Kieser Resistance Training Plus Kieser Pelvic Floor Training vs. Kieser Resistance Training Plus Traditional Pelvic Floor Exercise on Urinary Incontinence in Prostate Cancer Patients After Radical Prostatectomy
Surgical removal of the prostate (radical prostatectomy) is the most common therapy in prostate cancer patients. However, urinary incontinence often occurs as a side effect.
- Conditions
- Prostate Cancer, Prostate Ectomy, Pelvic Floor Disorders, Incontinence, Urinary
- Trial name
- RECON (NCT06206993)
- Testing
- Resistance training including the Kieser A5 pelvic floor trainer, Resistance training without pelvic floor biofeedback Kieser A5 pelvic floor trainer
- Where
- Germany
- Volunteers
- 99 people
- Sponsor
- University Hospital Heidelberg
Prostate Cancer, Incontinence
Is the HIFEM Procedure an Effective Treatment for Men With Post-prostatectomy Incontinence?
Urinary incontinence after radical prostatectomy surgery is a common condition that negatively affects daily life. Patients often experience discomfort due to urine leakage and the resulting need to use pads daily.
- Conditions
- Prostate Cancer, Incontinence, Pelvic Floor Muscle Weakness
- Trial name
- HIFEM for PPI (NCT06372704)
- Testing
- HIFEM
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Gynecologic Neoplasms
Safety of Regular Diet as the First Meal in Patients Who Underwent Surgical Treatment for Gynecologic Cancer
The purpose of this study is to determine whether it is safe to give a regular diet as the first postoperative meal in patients who underwent surgical treatment for clinically early-stage gynecologic cancer.
- Trial name
- NCT00328757
- Testing
- Regular diet as the first postoperative meal
- Where
- Thailand
- Volunteers
- 240 people
- Sponsor
- Chiang Mai University
BRCA1 Mutation, BRCA2 Mutation
Radical Fimbriectomy for Young BRCA Mutation Carriers
Some BRCA-mutated women are reluctant to undergo laparoscopic bilateral salpingo-oophorectomy. The goal of the bilateral laparoscopic radical fimbriectomy the investigators suggest, is to suppress the tubal source of possible…
- Conditions
- BRCA1 Mutation, BRCA2 Mutation, Hereditary Breast and Ovarian Cancer
- Trial name
- FIMBRIECTOMIE (NCT01608074)
- Testing
- Radical fimbriectomy, Histopathology SEE-FIM
- Where
- 14 sites in France
- Volunteers
- 123 people
- Sponsor
- Centre Oscar Lambret
Renal Pelvis Cancer
Radical Radiotherapy Versus Radical Surgery for UTUC
This study is a prospective cohort study, and the proposed plan is to recruit 30 patients with radical radiotherapy for renal pelvic ureteral cancer, according to the actual clinical situation, enrolling the same period of time…
- Trial name
- NCT06652009
- Testing
- Radical nephroureterectomy, Radical radiotherapy
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Cervical Cancer
Thunderbeat Technology vs Standard Bipolar Electro Surgery in Laparoscopic Radical Hysterectomy and Pelvic Lymphadenectomy for Cervical Cancer
This prospective randomized pilot study is aimed to verify if the operative time of a LRH with pelvic lymphadenectomy for early stage cervical cancer (FIGO stages IA2-IB1-IIA<2cm) and for advanced stage cervical cancer (FIGO…
- Trial name
- Thunder Cervix (NCT01717781)
- Testing
- Thunderbeat technology, Standard bipolar electrosurgery
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Catholic University of the Sacred Heart
Cervical Carcinoma
Clinical Study of Indocyanine Green Displaying Pelvic Nerve in Radical Operation of Cervical Cancer
Indocyanine green was injected intravenously into patients with cervical cancer before operation. The nerve development was observed by infrared imaging system during operation, which was used as the basis for nerve preserving…
- Trial name
- NCT05087264
- Testing
- Indocyanine green
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Bladder Cancer
S1011 Standard or Extended Pelvic Lymphadenectomy in Treating Patients Undergoing Surgery for Invasive Bladder Cancer
RATIONALE: Lymphadenectomy may remove tumor cells that have spread to nearby lymph nodes in patients with invasive bladder cancer.
- Trial name
- NCT01224665
- Testing
- therapeutic conventional surgery, therapeutic standard lymphadenectomy, therapeutic extended lymphadenectomy
- Where
- 35 sites in United States, Canada
- Volunteers
- 658 people
- Sponsor
- SWOG Cancer Research Network
Prostate Cancer
Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Androgens can cause the growth of prostate cancer cells.
- Trial name
- NCT00567580
- Testing
- PBRT, PLNRT, AA
- Where
- 460 sites in United States, Canada and 2 more
- Volunteers
- 1,792 people
- Sponsor
- Radiation Therapy Oncology Group
Rectal Cancer Surgery, Middle and Low Rectal Cancer
Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery
The goal of this clinical trial is to determine whether closing the pelvic floor peritoneum during laparoscopic radical resection of mid-low rectal cancer can reduce the incidence of postoperative ileus.
- Conditions
- Rectal Cancer Surgery, Middle and Low Rectal Cancer, Intestinal Obstruction, Ileus
- Trial name
- TOWER-1 (NCT07432542)
- Testing
- Pelvic floor peritoneum reconstruction
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sun Yat-sen University