Clinical trials: Radiculopathies
Cervical Radiculopathy, Cervical Radicular Pain
Investigation of the Effects of Interlaminar Epidural Steroid Injection on Upper Extremity Proprioception in Patients With Chronic Cervical Radiculopathy
Cervical radiculopathy is a common condition caused by irritation or compression of cervical nerve roots, often leading to unilateral neuropathic pain and functional impairment.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Proprioception
- Trial name
- NCT07307846
- Testing
- Interlaminar Epidural Steroid Injection (ILESI)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Marmara University
Radiculopathy
The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery
The median Orthopaedic surgery wait time in Canada is 36.7 weeks (Esmail 2008), thus there is a need to find alternative treatments for pathologies such as lumbar disc herniations (LDH).
- Trial name
- NCT01073995
- Testing
- Kenalog and Sensorcaine
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Horizon Health Network
Intervertebral Disc Disorders With Radiculopathy, Lumbar Region
The Effects of Perioperative Nutritional Optimization on Blood Markers
The purpose of this study is to see if taking an oral nutrition supplement (Ensure Nutrition Shake) before and after lumbar spine surgery affects blood tests related the nutritional status of patients.
- Trial name
- NCT04464161
- Testing
- Ensure
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Discogenic Low Back Pain
McKenzie Extension Protocol Versus Core Stability Exercises Combined With Spinal Decompression in Discogenic Lumbar Radiculopathy
The pathophysiology arises from structural and biochemical degeneration within the intervertebral disc rather than direct nerve root compression alone.
- Trial name
- D-MECS (NCT07730502)
- Testing
- McKenzie Extension Protocol, Core stability Exercise, Spinal decompression, Moist heat, interferential current
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Ibadat International University, Islamabad
Cervical Radiculopathy, Proprioception
Assessment of Upper Extremity Proprioception in Patients With Cervical Radiculopathy
There is no study in the current literature that systematically investigates the extent of upper-extremity proprioceptive impairment in patients with radicular neuropathic symptoms secondary to cervical disc herniation, nor its…
- Conditions
- Cervical Radiculopathy, Proprioception, Cervical Disc Herniation, Proprioception Reaching Test
- Trial name
- NCT07319156
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Radiculopathy
CBD for Chronic Radicular Pain on Chronic Opioid Therapy (COT)
This double-blind, placebo-controlled, exploratory trial is designed to compare effects of oral CBD 600mg to placebo (PCB) in 20 outpatients with chronic spinal radiculopathies (without co-occurring Opioid Use Disorder)…
- Trial name
- NCT04760613
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- NYU Langone Health
Spinal Cord Diseases
Reorganization of Brain Functions in Patients With Cervical Myelopathy Using fMRI and MRS
Decompressive surgery to relieve symptoms of spinal cord compression due to dysfunction, such as arthritis, has proved variable in success.
- Trial name
- NCT00447343
- Testing
- Decompressive cervical spine surgery, fMRI and MRS scan
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
Cervical Disc Disease, Cervical Radiculopathy
Rehabilitation After Anterior Cervical Discectomy and Fusion
Anterior cervical discectomy and fusion (ACDF) is a commonly performed surgical procedure for cervical disc herniation, cervical radiculopathy, and degenerative cervical spine disorders.
- Conditions
- Cervical Disc Disease, Cervical Radiculopathy, Postoperative Dysphagia
- Trial name
- ACDF-REHAB (NCT07814950)
- Testing
- Structured Postoperative Rehabilitation Program, Standard Postoperative Follow-up
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Cervical Radiculopathy
Effects of Neural Mobilization With or Without Soft Tissue Mobilization in Cervical Radiculopathy
This study will evaluate Effects of Neural Mobilization with or without Soft Tissue Mobilization in Cervical Radiculopathy, half of the subjects will receive treatment of Neural Mobilization along with Soft Tissue Mobilization…
- Trial name
- NCT03838315
- Testing
- Neural Mobilization with Soft Tissue Mobilization, Neural Mobilization without Soft Tissue Mobilization
- Volunteers
- 60 people
- Sponsor
- Isra University
Lumbar Radiculopathy
Comparative Effect Between Mulligan Leg Raise and Spinal Mobilization With Limb Movement in Lumbar Radiculopathy
This study examines the comparative effects of mulligan leg raise traction and Spinal Mobilization with Leg Movement (SMWLM) on lumbar radiculopathy
- Trial name
- NCT07887685
- Testing
- Mulligan Leg Raise traction, Spinal Mobilization with Limb Movement - SMWLM
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Low Back Pain
Interventional Study of Effects on Spine Height With Two Unloading Positions
The purpose of this study is to test a physical therapy intervention for reducing pain in the low back and into the legs. With individuals over the age of 40 years, this pain may be associated to changes in back height from aging…
- Trial name
- NCT01048749
- Testing
- aquatic vertical suspension., land-based supine flexion
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Texas Tech University Health Sciences Center
Cervical Degenerative Disc Disease
Real World Data Collection on the Synergy Disc
This is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts.
- Trial name
- NCT06383949
- Testing
- Synergy Cervical Disc system
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- Synergy Spine Solutions
Cervical Disc Herniation, Cervical Foraminal Stenosis
Endoscopic Posterior Cervical Foraminotomy Versus Anterior Cervical Discectomy and Fusion for Cervical Radiculopathy
Cervical radiculopathy caused by cervical disc herniation or foraminal stenosis is a common condition that may result in upper limb pain, sensory disturbances, and motor deficits.
- Conditions
- Cervical Disc Herniation, Cervical Foraminal Stenosis, Cervical Radiculopathy
- Trial name
- ENDOFOR (NCT07894159)
- Testing
- Uniportal Endoscopic Posterior Cervical Foraminotomy, Anterior Cervical Discectomy and Fusion
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Central Hospital, Nancy, France
Radiculopathy
Outcome of Physiotherapy After Surgery for Cervical Disc Disease: a Prospective Multi-Centre Trial
Many patients with cervical disc disease have long-lasting and complex symptoms with chronic pain, low levels of physical and psychological function and sick-leave.
- Trial name
- NCT01547611
- Testing
- Customary treatment, Structured behavioural medicine program
- Where
- 2 sites in Sweden
- Volunteers
- 202 people
- Sponsor
- Linkoeping University
Cervical Disc Degeneration
Real World Data Collection on the Synergy Cervical Disc
This trial is a real world data (RWD) collection observational study, comprised of both prospective and retrospective arms, that will examine the safety and effectiveness of the Synergy Cervical Disc System in patients with…
- Trial name
- NCT05305430
- Testing
- Synergy Cervical Disc System
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Synergy Spine Solutions
Radiculopathy
Management of Lumbar Discectomy by Endoscopy and Conventional Microscopic Discectomy
Currently, microscopic discectomy is performed as a minimally invasive surgery, thus reducing impact of so-called conventional "open" discectomies.
- Trial name
- ENDOLOMB (NCT06193265)
- Testing
- Discectomy
- Where
- France
- Volunteers
- 539 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Lumbar Radiculopathy
Different Dosage of Decompression Therapy on Symptoms of Lumbar Radiculopathy
This study will provide evidence about how much dose of decompression more effective for the treatment of lumbar radiculopathy. As this hypothesis has no evidence about the dosage of decompression in literature till now.
- Trial name
- NCT04852900
- Testing
- Decompression with 30%, Decompression with 40%, Decompression with 50%
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Riphah International University
Cervical Radiculopathy
Association Between Neck Disability Index Categories and Multidirectional Range of Motion in Patient With Cervical Radiculopathy
This study aims to investigate the association between NDI categories (None, Mild, Moderate, Severe) and ROM in six directions: flexion, extension, right and left side bending, and right and left rotation.
- Trial name
- NCT07152522
- Testing
- cross sectional observational
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Radiculopathy, Myelopathy
RHINE™ Cervical Disc Clinical Study: A Prospective Observational Study for Patients Requiring 1-2 Level C-spine Surgery
A Prospective, open label, multi-center observational study of patients requiring surgical treatment at one or two (contiguous) cervical spine levels.
- Conditions
- Radiculopathy, Myelopathy, Spondylosis, Herniated Nucleus Pulposus
- Trial name
- NCT02403453
- Testing
- Rhine Cervical Disc
- Volunteers
- 68 people
- Sponsor
- K2M, Inc.