Clinical trials: Randomised Clinical Trial
Healthy
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body
The main objective of this trial is to investigate relative bioavailability of BI 456906 reference formulation (Formulation A) vs. BI 456906 test formulation (Formulation B2).
- Trial name
- NCT07071974
- Testing
- BI 456906 formulation A, BI 456906 formulation B2
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Child Birth
Room 4 Birth - An Adaptable Birthing Room and the Effect on Labour and Birth
Healthcare Environment influences health outcomes. The effects of physical aspects of the birthing room on maternal and neonatal outcomes is insufficiently studied.
- Trial name
- R4B (NCT03948815)
- Testing
- interventional birthing room
- Where
- Sweden
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Bone Loss in Jaw
Comparison Between Single Implant Retained Partial Over-denture and Conventional Partial Denture
In this study we are going to evaluate patient satisfaction as well as the amount of bone loss on using single implant retained partial over-denture versus conventional partial denture for treatment of mandibular Kennedy class IV…
- Trial name
- NCT03324789
- Testing
- Single Implant Partial Over-denture, Conventional Partial Denture
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV
Depletion of Serum Amyloid P Component to Enhance the Immune Response to DNA Vaccination
This is a clinical proof-of-concept (PoC) study of DNA vaccination after SAP depletion. The investigators will measure the immune responses to DNA vaccination against HIV-1 in healthy adult male volunteers, comparing a group in…
- Trial name
- HIV-CORE003 (NCT02425241)
- Testing
- pSG2.HIVconsv DNA vaccine, ChAdV63.HIVconsv booster vaccine, MVA.HIVconsv booster vaccine
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University College, London
Bronchiolitis
A Study of Hypertonic Saline for Infants Hospitalized With Bronchiolitis
The purpose of this study is to determine if nebulized hypertonic saline (or extra salty water mist) helps infants less than 12 months old hospitalized with bronchiolitis (or bad chest colds) get better enough to be discharged…
- Trial name
- NCT01488448
- Testing
- 3% sodium chloride, 0.9% sodium chloride
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
L-PRF, Surgery
Root Coverage for Gingival Recessions: a Randomized Clinical Trial Using Coronally Advanced Tunnel Technique and Novomatrix®
A randomized clinical trial comparing the modified tunnel technique with the use of acellular xenogeneic matrix and connective tissue with the use leucocyte platlet rich fibrin (L-PRF)
- Trial name
- NCT06719648
- Testing
- Acellular dermal matrix + L-Prf, Connective Tissue graft + L-Prf
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Parkinson Disease
Efficacy of Pattern Respiratory PNF Associated Aerobic Training on Lung Volumes and 6MWT Test in Parkinson Individuals
INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative disorder that causes motor disorders such as bradykinesia, rigidity and tremor.
- Trial name
- NCT02600052
- Testing
- PNF, treadmill
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Major Depressive Disorder
Comparing Efficacy of Optimal Treatment and Conventional Treatment for Major Depressive Disorder in Viet Nam
Comparison of efficacy treatment (respond, remission) between the optimized treatment group (dose adjustment or early change other drug based on the change of total score HAM-D 17) and the routine treatment group (start with the…
- Trial name
- NCT04826614
- Testing
- optimized treatment
- Where
- Vietnam
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Satisfaction
Effectiveness of Office Bleaching Agents in Patients of Different Age Group
To evaluate the effectiveness in terms of color variation, patient satisfaction, absolute risk and intensity of dentin sensitivity due to dental bleaching in the office with 35% hydrogen peroxide (Whiteness HP Automixx 35%, FGM)…
- Trial name
- NCT03194984
- Testing
- Hydrogen peroxide 35%, Hydrogen peroxide 38%
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Nephrolithiasis, Staghorn Calculus
Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy
This study is a double blinded randomized controlled trial evaluating the impact of tranexamic acid use on the transfusion rate in patients with complex kidney stones undergoing percutaneous nephrolithotomy.
- Trial name
- NCT02966236
- Testing
- Tranexamic Acid
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Enamel Demineralization, White Spot Lesions
Silver Nanoparticle-Coated Orthodontic Brackets for Preventing Enamel Demineralization
The goal of this clinical trial is to learn whether orthodontic brackets coated with silver nanoparticles can help prevent early damage to tooth enamel in people receiving fixed braces.
- Trial name
- AgBracket (NCT07707336)
- Testing
- Silver Nanoparticle-Coated Stainless Steel Orthodontic Brackets, Conventional Stainless Steel Orthodontic Brackets
- Where
- United Arab Emirates
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ajman University
Premalignant Conditions, Malignant Lesions
To Evaluate the Best Metric for Inspection Time During a Diagnostic and/or Surveillance Upper Gastrointestinal Endoscopy (Age ≥ 18 Years, Informed Consent), Between Total Inspection Time Versus Withdrawal Time, for the Identification of Malignant Lesions
Gastric cancer is the fifth cause of cancer-related mortality worldwide. Gastric carcinogenesis involves the progression from premalignant conditions such as atrophic gastritis and intestinal metaplasia to premalignant lesions…
- Conditions
- Premalignant Conditions, Malignant Lesions, Gastric, Esophageal
- Trial name
- NCT06696209
- Testing
- Analysis of the withdrawal time of the Upper Gastrointestinal Endoscopy, Analysis of the total time of the Upper Gastrointestinal Endoscopy, Upper gastrointestinal endoscopy: Common Practices
- Where
- Portugal
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Primary Teeth, Dental Pulp Regeneration
Different Treatment Modality in Necrotic Primary Molars
Necrotic primary molars in preschool children will be treated with the regeneration concept to provide a healthy biological environment within the root canal system and regression in clinical signs and symptoms which are the…
- Trial name
- NCT04190914
- Testing
- pulp regeneration for necrotic primary teeth
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- dina darwish
Treatment Resistant Disorders
Adding L-carnitine in Clomiphene Resistant Polycystic Ovary Improves the Quality of Ovulation and the Pregnancy Outcome
Adding L-carnitine is more successful than clomiphene as a first line therapy for ovulation induction in women with clomiphene resistant PCOS
- Trial name
- NCT01665547
- Testing
- l-carnitine
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Orthodontic Appliance Complication
Chairside Time and Bond Failure of Non Custom Versus Custom Base Orthodontic Attachments During Indirect Bonding
compare the chair side time, clinical orthodontic attachment bond failure and accuracy of transfer between non custom attachment base and custom attachment base indirect techniques.
- Trial name
- NCT03365232
- Testing
- non custom base attachment, custom base attachment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Body Image, Eating Disorder Symptom
Evaluation of the Impact of a Comic-based Programme to Promote Body Confidence Among Adolescents in India
Body dissatisfaction is a leading concern for young people and can have serious health consequences. Emerging approaches for improving body image are effective among adolescents in the school setting.
- Trial name
- NCT04317755
- Testing
- AdhaFULL body image comics
- Where
- United Kingdom
- Volunteers
- 2,631 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Anesthesia, In-vitro Fertilization
A Comparison of Sedation/Analgesia & LMA on Anxiety Level and Patient Satisfaction in In-Vitro Fertilization
In vitro fertilization (IVF) is a new expertise of our age. Anesthesia during the assisted reproduction technique is usually required during oocyte removal, which is one of the basic steps throughout the entire procedure.
- Conditions
- Anesthesia, In-vitro Fertilization, Analgesia
- Trial name
- IVF (NCT03814330)
- Testing
- State-Trait Anxiety Inventory, Quality of Recovery Score, Sedation/Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Inonu University
Language Development
Evaluating the Impact of Story Starters on Children's Language Development
The aim of this project is to evaluate whether Beanstalk's 'Story Starters' intervention is effective in boosting vocabulary and grammatical development in young children.
- Trial name
- NCT03268928
- Testing
- Story Starters Intervention, Wait-list Control
- Where
- United Kingdom
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Julian Pine
Dental Restoration, Dental Implant
Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns
To compare biological, technical, radiographic, and patient-reported outcomes of two types of monolithic zirconia crowns screw-retained to implant.
- Trial name
- NCT06417632
- Testing
- Graded Zirconia Crown, Conventional Zirconia Crown
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Airway Obstruction
Maxillary Expansion Effects in Children With Upper Airway Obstruction
The most frequent causes of mouth breathers are the adenotonsillar hypertrophy. Adenotonsillectomy is the main choice for the elimination of the obstruction.
- Trial name
- NCT03004300
- Testing
- Rapid maxillary expansion, Adenotonsillectomy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
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