Clinical trials: Randomised Clinical Trial
Osteoarthritis, Knee
Medial Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty
In treatment of isolated medial unicondylar osteoarthritis of the knee (MU-OA), it is possible to choose between surgery with a unicondylar knee arthroplasty (UKA), or a total knee arthroplasty (TKA).
- Trial name
- UKAvsTKA (NCT03396640)
- Testing
- Unicondylar Knee Arthroplasty, Total Knee Arthroplasty
- Where
- 11 sites in Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Healthy
Does Perineural Clonidine Prolong Duration of a Nerve Block?
The aim of this trial is to investigate if clonidine prolongs the duration of an adductor canal block. By using healthy volunteers the investigators can perform a bilateral adductor canal block and thereby control for a systemic…
- Trial name
- NCT02444559
- Testing
- Ropivacaine 20ml 5mg/ml+ Clonidine 150ug
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Fetal Surveillance, Intrauterine Growth Restriction
Comparison of Follow-up Protocols in Terms of Fetal, Neonatal and Maternal Results in Intrauterine Growth Retardation
This study will be undertaken to determine whether the frequency of fetal surveillance can be safely reduced from bi-weekly to weekly in the case of fetusus with intrauterine growth restriction.
- Trial name
- NCT04141189
- Testing
- weekly, bi-weekly
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dental Implants
Comparision of Clinical Efficacy of Immediate Implants With T-PRF and Bone-graft Versus PRF and Bone-graft
The normal architecture of the alveolar process is altered by periodontitis, which also causes the loss of alveolar bone surrounding the teeth. Untreated periodontitis may cause teeth to become mobile and leads to loss of teeth.
- Trial name
- NCT06525324
- Testing
- Immediate implant surgery with T-PRF and xenograft, Immediate implant surgery with PRF and xenograft
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Healthy Volunteers, Growth Hormone Deficiency
A Study to Compare the Uptake Into the Blood of Two Strengths of Somapacitan After Injection Under the Skin in Healthy Subjects
This study will compare two strengths of the new long-acting growth hormone somapacitan. The aim of this study is to test if both strengths are taken up in the blood in the same way.
- Trial name
- NCT03905850
- Testing
- somapacitan
- Where
- Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Oral Ulcer
Clinical Efficiency of Natural Herbal Based Gel.
This clinical trial was conducted in School of Dentistry, Islamabad from 15th June 2023 to 16th January 2024. A total 202 participants took part in study and were divided equally into two groups i.e Control group and Experimental…
- Trial name
- NCT06490289
- Testing
- Denpro oral gel
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Nutrition, Healthy
Testing the Veggie Brek Intervention
This programme of work aims to investigate the feasibility and acceptability to both children and nursery staff of offering vegetables to children at breakfast time at nursery.
- Trial name
- NCT05217550
- Testing
- Veggie Brek
- Where
- United Kingdom
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Malaria, Cerebral
Rehabilitation Program for Cognitive Deficits in Ugandan Children After Cerebral Malaria
The purpose of this study is to determine whether computerised cognitive rehabilitation training improves cognition in children who have had cerebral malaria.
- Trial name
- NCT00658450
- Testing
- Cognitive rehabilitation training
- Where
- Uganda
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Makerere University
Anxiety
Feasibility Study of a Music and Social Support Intervention for Postnatal Mothers/Infants
This research study aims to assess the feasibility of conducting a full scale trial of Mamas in Harmony, a group music and social support class delivered by a professional musician for mothers and their babies.
- Trial name
- NCT05930990
- Testing
- Mamas in Harmony
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Muscle Weakness, Osteoporosis, Postmenopausal
Assessing the Effect of Shatavari Supplementation on Bone and Skeletal Muscle Health in Healthy Postmenopausal Women
Shatavari is a plant that grows in Nepal, Sri Lanka, India and the Himalayas and its root has long been used in Ayurvedic medicine.
- Trial name
- NCT05025917
- Testing
- Shatavari, Magnesium stearate
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Psychological Stress
A Randomised Controlled Trial of Self-help Mindfulness-based Cognitive Therapy for Health Workers
This study examines whether a mindfulness-based self-help book is effective at reducing healthcare workers' levels of stress and improving their wellbeing.
- Trial name
- MindSHINE2 (NCT03030040)
- Testing
- The self-help book: Williams, M. & Penman, D. (2011). Mindfulness: A practical guide to finding peace in a frantic world. London: Piatkus.
- Where
- 2 sites in United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Depression, Anxiety
Online Support Groups for Depression and Anxiety
The purpose of this study is to determine the effectiveness of online support groups for anxiety and depression.
- Trial name
- NCT01149265
- Testing
- Online support group, Expressive writing
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children
Plaque Removal in Children Using Charcoal and Nylon Toothbrushes
This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush.
- Trial name
- NCT07563400
- Testing
- soft charcoal infused bristle toothbrush (iLive) with bamboo handle, soft nylon bristle toothbrush (Oral B JUNIOR 6-12)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Retruded Hypoplastic Maxilla
Comparison Between Prebent & Miniplates in Fixation of Lefort I Osteotomty in Maxillary Advancement.
In patients with retruded maxilla ,Will the use of two prebent plates produce more stable results postoperatively in fixation of Le Fort I osteotomy in maxillary advancement than conventional four minplates ? Many studies have…
- Trial name
- NCT03752944
- Testing
- lefort I osteotomy for maxillary advancement
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Kinesiophobia
Impact of Kinesiophobia on Descending Corticospinal and Bulbospinal Projections
Fear of movement (kinesiophobia) is a phenomenon commonly observed in people suffering from chronic pain. The aims of this project are to better understand the neurophysiological basis of this phenomenon, in particular 1) the…
- Trial name
- EchoKinésio (NCT05161832)
- Testing
- Nocebo
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Motor Learning
Brain Training Tools With Physical Practice on Motor Learning
This study evaluates the influence of motor imagery and action observation in combination with physical practice on motor learning
- Trial name
- NCT04129307
- Testing
- Motor imagery, Double time motor imagery, Action observation
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Visual Stress
The ARUTIS Study (Anglia Ruskin University Trial of the Intuitive System)
The goal of this double-masked randomised controlled trial (RCT) is to assess the symptoms of visual stress (VS), reading speed and changes in behaviour / academic performance, when wearing optimal Precision Tinted Lenses…
- Trial name
- ARUTIS (NCT06093516)
- Testing
- Tinted Lenses
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Functional Status, Muscle Tone
Effects of Cryotherapy on Upper Limb Balance Test
The shoulder joint is commonly used and also stricken by high loads and injuries in sports. One technique in emphasis is cryotherapy, a physiotherapeutical intervention characterized by the use of low temperatures for tissue…
- Trial name
- NCT05318664
- Testing
- Cryotherapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Flávia Carvalho
The Efficacy of Percutaneous Catheter vs. Open Chest Tube, Traumatic Hemothorax
Multi-center:The Small (14F) Percutaneous Catheter vs. Large (28-40F) Open Chest Tube for Traumatic Hemothorax (P-CAT)
After sustaining severe trauma to the chest, patients will often bleed into the chest cavity (pleural space) which is called hemothorax or they may also experience air leakage within the chest cavity in combination with the…
- Trial name
- P-CAT (NCT03546764)
- Testing
- Percutaneous catheter
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Arizona
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