Clinical trials: Randomised Clinical Trial
Dietary Modification
Trial of Different Dietary Fat Sources on Blood Lipids and Other CVD Risk Factors
This is a randomised trial in which healthy volunteers, men and women aged 50-75 years from the general community are randomized into one of three arms: participants will be provided with 50 gm extra virgin coconut oil, or 50…
- Trial name
- COCHEESE (NCT03401281)
- Testing
- Coconut oil, Butter, Olive oil
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Reading
Self Efficacy, Nursing
A Blended Learning to Enhance Communication Skill Competence and Self-Efficacy of Nursing Students in Clinical Handovers
This study aimed to examine the efficacy of a blended learning programme in enhancing the communication skill competence and self-efficacy of final-year nursing students in conducting clinical handovers.
- Conditions
- Self Efficacy, Nursing, Communication
- Trial name
- NCT05150067
- Testing
- A Blended Learning Programme, Waitlist control group
- Where
- Hong Kong
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Healthy
Pharmacokinetics of Simvastatin and Its Metabolite Simvastatin Acid With and Without Concomitant Administration of Telmisartan in Healthy Subjects
To assess the pharmacokinetics of simvastatin and simvastatin acid with/without concomitant administration of telmisartan
- Trial name
- NCT02187536
- Testing
- Telmisartan, Simvastatin
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Influenza
A Randomised Controlled Trial on the Effect of Post-exposure Oseltamivir Prophylaxis on Influenza Transmission in Nursing Homes
The incidence of severe morbidity and mortality following an influenza infection during the annual influenza epidemics is highest among the elderly population and 90% of influenzaassociated mortality occurs in this group.
- Trial name
- PEPpIE (NCT01053377)
- Testing
- Tamiflu (verum)
- Where
- Netherlands
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute for Public Health and the Environment (RIVM)
Dental Caries in Children, Tooth Diseases
Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars
The purpose of this randomized clinical trial is to compare the clinical/radiographic success of Hall technique and modified Hall technique in the treatment of primary molars with deep dentine carious lesions in children…
- Conditions
- Dental Caries in Children, Tooth Diseases, Tooth Demineralization, Stomatognathic Diseases
- Trial name
- NCT05220865
- Testing
- Hall Technique, Modified Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Caries Prevention
Retention Rate of Giomer Pit and Fissure Sealant Applied With or Without Etching
The aim of this study is to evaluate the retention rate of Giomer S-PRG filler containing pit and fissure sealant applied with or without etching by using split mouth technique.with null hypothesis that Giomer S-PRG filler…
- Trial name
- NCT06509451
- Testing
- Giomer pit and fissure sealant without etching, Giomer pit and fissure sealant with etching
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hearing Aids
Remote Hearing Aid Adjustment for Experienced Hearing Aid Users
Many hearing aid users experience substantial communication difficulties that may affect their participation in daily life situations negatively.
- Trial name
- RCT (NCT04840277)
- Testing
- Remote hearing aid adjustment
- Where
- Sweden
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Sodra Alvsborgs Hospital
Partial Caries Removal
Clinical and Radiographic Evaluation of Deep Occlusal Carious Molars Treated With Partial Caries Removal With and Without Using Silver Diamine Fluoride (SDF) Prior to Resin Composite Restoration.
The aim of the study is to evaluate the effect of SDF in maintaining pulp health after partial caries removal in permanent teeth with deep occlusal carious lesion clinically and radiographically
- Trial name
- NCT04561934
- Testing
- Silver diamine fluoride, resin modified glassionomer cement
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Physical Activity
Take A Stand for Workplace Health: A Sit-stand Workstation Project Evaluation
The purpose of this study is to examine the contribution of sit-stand workstations to total daily physical activity in a multi-component office-based 12 month intervention.
- Trial name
- NCT02172599
- Testing
- Sit-stand workstation provision
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brunel University
Healthy
A Study in Healthy People to Test How BI 425809 is Taken up in the Body When Taken With or Without Food
The main objective of this trial is to investigate the potential effect of food on the pharmacokinetics of BI 425809 following administration of the intended Commercial Formulation (iCF) with food (Test treatment, T) and without…
- Trial name
- NCT05347004
- Testing
- BI 425809
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Nursing Education Research
World Café Teaching on Pharmacology Academic Performance and Perceived Self-Regulated Learning Among Nursing Students
This exploratory two-round cluster-randomised trial examined the World Café teaching method, a structured participatory approach, in pharmacology education for third-year undergraduate nursing students.
- Trial name
- NCT07601984
- Testing
- World Café Teaching Method, Traditional Lecture Method
- Where
- China
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- Ying Guo
Obesity, Overweight
Early Stockholm Obesity Prevention Program
To study whether a targeted intervention can prevent the development of overweight and obesity among pre-school children in families with either one obese or two overweight parents.
- Trial name
- EarlySTOPP (NCT01198847)
- Testing
- Dietary, physical activity and sleeping
- Where
- Sweden
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Maxillary Sinus, Allograft
Maxillary Sinus Augmentation Using CAD/CAM Allogenic Bone Blocks Versus Particulate Allogenic Grafts
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups Group I: sinus lifting using CAD/CAM allogenic block through lateral window…
- Trial name
- NCT07604155
- Testing
- sinus lifting using CAD/CAM allogenic block, sinus lifting using particulate allogenic graft
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Tanta University
Frail Elderly, Coronary Artery Disease
Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients
Frailty is defined as a geriatric syndrome of impaired resiliency to stressors (such as cardiac surgery) that has been delineated recently in the cardiovascular literature.
- Trial name
- FRAGILE (NCT02338947)
- Testing
- Off-pump coronary-artery bypass grafting, On-pump coronary-artery bypass grafting
- Where
- 7 sites in United States, Brazil
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Sleep Bruxism, Monolithic Ceramic Fixed Dental Prosthesis (Single Crowns)
All-ceramic Crowns in Patients With Sleep Bruxism
The aim of the study is to evaluate the complication rate of 2 types of all-ceramic crowns in patients with or without bruxism.
- Trial name
- NCT03039985
- Testing
- Zirconia crowns (Prettau®), lithium disilicate crowns (IPSe.max®)
- Where
- Germany
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Surgical Simulation Education
Development and Evaluation of Low-Cost Non-Animal Biological Simulation Models for Undergraduate Surgical Training in Trauma Tissue Reconstruction
This study evaluated two low-cost, non-animal biological simulation models for teaching basic surgical skills to undergraduate medical students.
- Trial name
- NCT07820345
- Testing
- Suturing Simulation Training, Tendon Repair Simulation Training
- Where
- India
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Preterm Infant, Umbilical Cord Milking
Effect of Intact Umbilical Cord Milking on Neonatal and First Year Neurodevelopmental Outcomes in Very Preterm Infants.
The investigators hypothesise that intact umbilical cord milking (I-UCM) will reduce neonatal morbidity and improve long term neurodevelopmental outcome in very preterm infants.
- Trial name
- Cord-milking (NCT03200301)
- Testing
- Intact Umbilical Cord Milking
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Ankle Stiffness
Comparison of Two Manual Therapy Techniques on Ankle Dorsiflexion
Ankle rigidity is a common musculoskeletal disorder affecting the talocrural joint, which can impair weight-bearing ankle dorsiflexion (WBADF).
- Trial name
- NCT02653807
- Testing
- mobilization with movement, osteopathic mobilization
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Pain Management
Nurse-led Pain Management in Adult ICU
This project is about implementing a pain scale, the Critical Care Pain Observation Tool (CPOT), in ICU settings at King Abdullah Medical City to evaluate its impact on nurse pain assessment and management.
- Trial name
- NCT05488834
- Testing
- Critical-Care Pain Observation Tool
- Where
- Saudi Arabia
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Oral Potentially Malignant Disorders, Alcohol Drinking
Role of the Dentist in the Control of the Alcoholic Habit in Patients with Potentially Malignant Oral Lesions
Introduction: Alcohol is the most consumed psychoactive substance, its consumption is very prevalent and there is a low perception of the risk it poses in our society.
- Trial name
- ALCODENT (NCT04584333)
- Testing
- Brief intervention
- Where
- Spain
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
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