Clinical trials: Randomised Controlled Trial
Preterm Infant, Umbilical Cord Milking
Effect of Intact Umbilical Cord Milking on Neonatal and First Year Neurodevelopmental Outcomes in Very Preterm Infants.
The investigators hypothesise that intact umbilical cord milking (I-UCM) will reduce neonatal morbidity and improve long term neurodevelopmental outcome in very preterm infants.
- Trial name
- Cord-milking (NCT03200301)
- Testing
- Intact Umbilical Cord Milking
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Cholera
Simulation Based Training In Medical Students
Transferring classroom learning to real-life situations is a challenge. Tabletop simulation exercises offer a low-cost and context-specific approach for educating students on appropriate responses during health emergencies.
- Trial name
- NCT06929312
- Testing
- Tabletop simulation based teaching, conventional class room teaching
- Where
- Pakistan
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Osteoarthritis of Knee, Central Sensitization
Duloxetine As an Analgesic in Patients Without Central Sensitivity After Same Sitting Bilateral Total Knee Arthroplasty
Analgesic effect of 20mg Duloxetine was evaluated at regular short term intervals in patients without central sensitivity and undergoing bilateral single sitting total knee arthroplasty for tricompartmental osteoarthritis using…
- Conditions
- Osteoarthritis of Knee, Central Sensitization, Central Sensitisation
- Trial name
- NCT06837012
- Testing
- Duloxetine - low dose
- Where
- India
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Arthroscopy Knee and Shoulder Clinic
Cognitive Development
Testing Whether a Short Training Program Designed to Improve Cognitive Skills Improves 4-year-olds' Maths Skills
This study will test whether a short training program - designed to improve memory and attention skills - will benefit mathematical reasoning in preschoolers from a range of socio-economic backgrounds.
- Trial name
- NCT03063411
- Testing
- Executive Function Intervention, Active Control Group
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Metabolism and Nutrition Disorder, Obesity
A Trial to Assess the Effect of Liraglutide on Gastric Emptying in Healthy Obese Volunteers
This trial is conducted in Europe. The aim of this clinical trial is to investigate the effect of liraglutide on gastric emptying, energy expenditure and appetite, and to evaluate liraglutide pharmacokinetics in non-diabetic…
- Trial name
- NCT00978393
- Testing
- liraglutide
- Where
- Netherlands
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Influenza
A Randomised Controlled Trial on the Effect of Post-exposure Oseltamivir Prophylaxis on Influenza Transmission in Nursing Homes
The incidence of severe morbidity and mortality following an influenza infection during the annual influenza epidemics is highest among the elderly population and 90% of influenzaassociated mortality occurs in this group.
- Trial name
- PEPpIE (NCT01053377)
- Testing
- Tamiflu (verum)
- Where
- Netherlands
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute for Public Health and the Environment (RIVM)
Mental Health Help-Seeking
The Elite Athlete Mental Health Strategy Trial
The purpose of this study is to determine whether positive mental health help-seeking attitudes, and behaviour in elite athletes can be increased through an online intervention.
- Trial name
- TEAMS (NCT00940732)
- Testing
- Destigmatisation and Mental Health Literacy, Help-seeking list, Feedback
- Where
- Australia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Amelia Gulliver
Treatment Adherence and Compliance
Quality and Effectiveness of a Personalised App to Support Patients With Fixed Braces
Mobile phones are potentially an invaluable tool in improving adherence, they are readily available and can utilised to deliver several approaches to improve adherence simultaneously.
- Trial name
- NCT04184739
- Testing
- My Braces App
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University College, London
Hearing
The Effect of a Removable Complete Denture Over One Implant in the Lower Jaw on Hearing Ability
The effect of a removable complete denture and the insertion of one implant in the lower jaw and the loading of this implant on the hearing ability of patients will be studied, so the hearing ability will be measured by using the…
- Trial name
- NCT05744830
- Testing
- Overdenture, Complete Denture
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University
Polycystic Ovary Syndrome
Effect of Aerobics on Physical and Mental Health in Polycystic Ovary Syndrome
Polycystic ovary is one of the most common metabolic and endocrine disorders in women of reproductive age group. The Rotterdam criteria are used internationally for its diagnosis.
- Trial name
- NCT05577949
- Testing
- Structured aerobics exercise
- Where
- 4 sites in Pakistan
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Muhammad Irfan
Premature Infants
Therapeutic Touch in Premature Infants
Preterm birth is associated with increased physiological instability, stress responses, and developmental vulnerability due to immature organ systems and prolonged exposure to invasive procedures and environmental stressors in…
- Trial name
- NCT07363785
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Urinary Tract Infection
Cranberry for the Prevention of Urinary Tract Infections
This study aims to determine whether a cranberry concentrate reduces recurrent urinary tract infections (UTIs) in women. Approximately 150 adult women will be recruited to participate in this study.
- Trial name
- NCT02454309
- Testing
- Cranberry concentrate
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Fracture of Clavicle
Conservative Interventions for Treating Clavicle Fractures in Adults
Background: Fracture of the clavicle is common accounting for 2.6% to 4 % of all fractures, with an overall incidence of 36.5 to 64 per 100,000 per year. Around 80% of clavicle fractures occur in the middle third of the clavicle.
- Trial name
- NCT02398006
- Testing
- a standard arm sling, a figure-of-eight bandage
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Healthy Adolescents
EyeBreathe: A Mixed Reality Game With Eye Tracking and Breathing Biofeedback for Adolescent Basketball Players - A Randomised Controlled Trial
This randomised controlled trial will evaluate the effects of integrating a standalone mixed-reality (MR) breathing and eye-gaze training intervention (EyeBreathe) into regular basketball practice for adolescent athletes in…
- Trial name
- EyeBreathe-RCT (NCT07871331)
- Testing
- Breathing MR
- Where
- 2 sites in Latvia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Stress
Feasibility and Efficacy of a Digital Training Intervention to Increase Reward Sensitivity- Imager
Development and feasibility test of an Ecological Momentary Intervention (EMI) - Imager, to promote and improve stress resilience, specifically to increase reward sensitivity.
- Trial name
- IMAGER (NCT05623826)
- Testing
- Cognitive- behavioral imagery-based training
- Where
- Switzerland
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy Young Adults
Exergaming Versus Gym-based Exercise for Postural Control, Flow and Technology Acceptance
Balance training is an important component of physical fitness, however due to the mundane and often repetitive nature of balance training alone this is often forgotten about and as a result people may be more susceptible to…
- Trial name
- NCT02851017
- Testing
- Exercise
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Northumbria University
COVID-19
Evaluation of COVID-19 Vaccines Given as a Booster in Healthy Adults in Indonesia (MIACoV Indonesia)
This is a randomised controlled clinical trial to determine the reactogenicity and immunogenicity of booster doses of SARS-CoV-2 vaccines (Pfizer-BioNTech, AstraZeneca or Moderna) in adults who have previously received either…
- Trial name
- NCT05387317
- Testing
- Pfizer-BioNTech Standard dose, AstraZeneca Standard dose, Pfizer-BioNTech Fractional dose
- Where
- 3 sites in Indonesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
HIV Infections
Safety and Efficacy Trial of a Dapivirine Vaginal Matrix Ring in Healthy HIV-Negative Women
This is a double-blind, randomised, placebo-controlled study to assess the safety and efficacy of a silicone elastomer vaginal matrix ring.
- Trial name
- NCT01539226
- Testing
- Dapivirine Vaginal Ring, 25 mg
- Where
- 7 sites in South Africa, Uganda
- Volunteers
- 1,959 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Quality of Life, Appetite
Effects of a Collagen Supplement on Quality of Life, Appetite and Glycaemic Control
This is a clinical trial aimed to investigate if a collagen supplement can improve quality of life, appetite and blood sugar in overweight and obese adults aged 18-65.
- Conditions
- Quality of Life, Appetite, Sleep, Mood
- Trial name
- GluCol (NCT07229014)
- Testing
- Collagen peptide supplement
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College London
Autism Spectrum Disorder, Autism
Music for Autism (M4A)
The Music for Autism (M4A) trial evaluates the neurobehavioral outcomes of a music therapy (MT) intervention, compared to a matched play therapy (PT) intervention, on social communication skills, brain connectivity and structural…
- Trial name
- M4A (NCT04936048)
- Testing
- Music Therapy, Play therapy
- Where
- 2 sites in Austria, Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- NORCE Norwegian Research Centre AS