Clinical trials: Randomized Clinical Trial
Ambulatory Hand Surgery
Patient Education and Use of Post Operative Pain Medication in Ambulatory Hand Surgery: a Randomized Controlled Trial
There is a current opioid epidemic in the United States partially fueled by excess prescribing practices after surgery. The objective of this study is to decrease the amount of opioids needed after ambulatory hand surgery.
- Trial name
- NCT03219177
- Testing
- Patient education regarding indications for opioid use and side effects of opioid use after hand surgery, Standard of care post-operative counseling
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Training in Knowledge and Skills for Nursing Students in a Metaverse Environment
The Metaverse-Based Simulation on Nursing Students
Background: : Modern nursing education is moving away from the traditional model, which relies on the rote memorization of theoretical knowledge, and is evolving toward innovative learning methods that can enrich the learning…
- Trial name
- NursingEduct (NCT07577557)
- Testing
- learning
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Esin Cetinkaya Uslusoy
Pharmacokinetics
Single-dose AQ001S PK Study in Healthy Volunteers
This is a randomized, open label, single-center, single-dose, four-period crossover clinical study to assess the pharmacokinetic profile and safety of a budesonide inhalation solution (AQ001S) compared to a budesonide inhalation…
- Trial name
- BORA (NCT05148312)
- Testing
- Budesonide Inhalant Product
- Where
- Bulgaria
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Aquilon Pharmaceuticals S.A.
Pregnancy
The Effectiveness of The Breathing Exercise On The Nausea, Vomiting And Breathing Exercise In Pregnancy
Aim: This study aimed to investigate the effectiveness of the breathing exercise on pregnancy-related nausea and vomiting and the quality of life in the early pregnancy period.
- Trial name
- NCT05780112
- Testing
- breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Inonu University
Aging
Ergospirometric Values and WBV in Elderly
this study aims evaluate the ergospirometric values after 03 months of training with WBV in elderly health people. The hypothesis is increases of ergospirometric values.
- Trial name
- EVAWIE (NCT01681719)
- Testing
- WBV and Resistance
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Anxiety, Depression
Exploring the Efficacy of Treatments for Anxiety and Depression Among College Students
The goal of this randomized control group is to learn about effective treatments for college students experiencing anxiety and/or depression.
- Trial name
- NCT06013930
- Testing
- External Qigong, Mindfulness Meditation, Psychoeducation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of South Dakota
Insulin Resistance Syndrome
Aerobic and Strength Training With Caloric Restriction on Insulin Resistance in Obese Premenopausal Women
A total of 42 premenopausal women diagnosed clinically as having insulin resistance. Their ages ranged from 35 to 45 years old; their body mass index was >30 kg/m2 and They were obese women complained of insulin resistance and…
- Trial name
- NCT03716336
- Testing
- Resistance exercise, Aerobic exercise, diet restriction
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Volunteers
Trial on Single/Multiple Ascending Doses for Safety, PK and PD for CBP-0276 in Healthy Subjects
A double-blind, randomized, placebo-controlled, single and multiple ascending dose study with food effect to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of CBP-0276.
- Trial name
- CBP276SADMAD (NCT07708831)
- Testing
- CBP-0276 Acetate
- Where
- 2 sites in Mexico
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Clarent Biopharma, Inc.
Root Resorption
Correlation Between Root Resorption and Dentin Sialoprotein Upon Application of Different Orthodontic Forces.
Since root resorption is a frequent consequence of orthodontic treatment, DSP are non-collagenous dentin-specific matrix proteins postulated to be involved in the mineralization of pre-dentin into dentin.
- Trial name
- NCT03644537
- Testing
- Orthodontic intrusion
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Aya Ahmed Moursi El Faham
Caries, Salivary Function
Lesion Progression After Icon Treatment in Young Adults
This is a three year single site clinical evaluation of a FDA approved (510(k):K100062) lesion penetrating resin used to infiltrate and hamper progression of proximal carious lesions.
- Conditions
- Caries, Salivary Function, Tooth Sensitivity
- Trial name
- NCT01988337
- Testing
- Resin infiltration, Mock treatment
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Hypertension Patients
Hypertension Patients on Drug Medication Adherence and Rational Medication Use
This research will be conducted to determine the effects of education and telephone counseling given to hypertension patients on drug treatment compliance and rational drug use.
- Trial name
- NCT05060575
- Testing
- Education and Telephone Counceling
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ordu University
HIV Infections
A Phase IIA Trial to Evaluate the Safety and Immunogenicity of a DNA HIV-1 Vaccine Followed by an MVA HIV-1 Vaccine in HIV-uninfected Volunteers
The purpose of this study is to evaluate the safety and tolerability of plasmid DNA and recombinant MVA (Modified Vaccinia Virus Ankara) in a prime-boost regimen.
- Trial name
- NCT01371175
- Testing
- DNA.HIVA, MVA.HIVA
- Where
- 2 sites in Kenya, United Kingdom
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
Bias, Racial, Bias, Sex
Effect of Physician Race and Gender on Simulated Patients' Ratings
The purpose of the study was to determine whether the race and gender of a simulated doctor affected analog patients' reported confidence and satisfaction in the simulated doctor's diagnosis and treatment plan.
- Conditions
- Bias, Racial, Bias, Sex, Patient Satisfaction, Physician-Patient Relations
- Trial name
- NCT04190901
- Testing
- Simulated Black Male Physician, Simulated Black Female Physician, Simulated White Male Physician
- Where
- United States
- Volunteers
- 3,592 people, healthy volunteers welcome
- Sponsor
- Yale University
Humeral Diaphyseal Fracture
Operative and Nonoperative Treatment of Humeral Shaft Fractures
The purpose of this research study is to compare two different ways of treating a broken arm (fractured humerus) using either, the nonoperative approach or the operative, open reduction and internal fixation (ORIF).
- Trial name
- NCT00878319
- Testing
- Open reduction and internal fixation (ORIF), Non-surgical
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Carpal Tunnel Syndrome
Acute Effect of Topical Menthol on Carpal Tunnel Syndrome
Topical menthol gels are classified 'topical analgesics' and are used to relieve pain of the musculoskeletal system. However, double-blind randomized controlled trials are lacking.
- Trial name
- IRMA (NCT01716767)
- Testing
- Menthol
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Intimate Partner Violence (IPV)
Familia Imara: A Parenting Program to Reduce Family Violence in Tanzania
This cluster-randomized controlled trial will evaluate the effectiveness, implementation, and scalability of Familia Imara, a group-based, couples-focused, community health worker (CHW)-delivered parenting program, on reducing…
- Trial name
- NCT07574567
- Testing
- Familia Imara
- Where
- Tanzania
- Volunteers
- 6,216 people, healthy volunteers welcome
- Sponsor
- Saini Das
Obesity & Overweight
Effect of Intermittent Fasting and Mediterranean Diet on Body Composition and Nutritional Intake
Cardiovascular diseases (CVD), cancer, diabetes, stroke, and chronic lung diseases are non-communicable diseases (NCDs) and account for a significant portion of deaths worldwide.
- Trial name
- Obesity (NCT07378267)
- Testing
- Mediterranean diet, intermittent fasting
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Dental Implant Failed, Jaw, Edentulous, Partially
Osseodensification Versus Conventional Drilling for Implant Site Preparation
A total of 34 participants, who require replacement of an anterior or posterior single tooth with dental implant, will be randomly allocated to two equal sized groups.
- Conditions
- Dental Implant Failed, Jaw, Edentulous, Partially, Edentulous Alveolar Ridge, Osseointegration Failure of Dental Implant
- Trial name
- NCT06034067
- Testing
- Osseodensification osteotomy preparation, Standardized osteotomy preparation
- Where
- United Arab Emirates
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
COVID-19, Virus Diseases
Bacillus Calmette-guérin Vaccination to Prevent COVID-19
Based on findings of the interim analysis of the ACTIVATE study showing 53% decrease of the incidence of all new infections with BCG vaccination, a new trial is designed aiming to validate if BCG can protect against COVID-19…
- Conditions
- COVID-19, Virus Diseases, Corona Virus Infection, Coronary Heart Disease
- Trial name
- ACTIVATEII (NCT04414267)
- Testing
- BCG vaccine
- Where
- 15 sites in Greece
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Hellenic Institute for the Study of Sepsis
Pathology Foundation Model
AI Models in Clinical Pathology Diagnosis: A Multicenter RCT
The investigators plan to conduct a multicenter, prospective, randomized controlled trial to systematically evaluate the incremental value of pathology-based artificial intelligence (AI) models in a pan-disease diagnostic…
- Trial name
- NCT07408167
- Testing
- AI model, Control
- Where
- 3 sites in China
- Volunteers
- 2,060 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
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