Clinical trials: Randomized Clinical Trial
HIV Infections, Opioid-Related Disorders
Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug Users
Drug abuse and HIV/AIDS are serious global health problems. Injection drug use is currently the major mode of transmission of HIV in many countries.
- Trial name
- NCT00270257
- Testing
- Buprenorphine/Naloxone
- Where
- 4 sites in China, Thailand
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
A Study of a Probiotic Food Supplement Containing B. Infantis (EVC001) in Healthy Breastfed Infants at Risk of Developing Atopic Dermatitis
The purpose of this study is to assess the effect of B. infantis (EVC001) versus placebo supplementation, in healthy breastfed infants at risk of developing atopic dermatitis (AD), on cumulative incidence of physician-diagnosed…
- Trial name
- NCT04662619
- Testing
- B. infantis
- Where
- Finland
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Educational Problems
PBP vs Traditional Training: the T-REC Trial
This randomized controlled trial aims to compare the effectiveness of traditional training approach to training with the proficiency-based progression (PBP) approach for teaching the technical skills (TS) and non-technical skills…
- Trial name
- T-REC (NCT06147128)
- Testing
- Emergency scenario in a simulated setting where open conversion is necessary due to vessel injury during robotic surgery on a dry lab model
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Orsi Academy
In Vitro Fertilization (IVF), Embryo Transfer
Dual Trigger With HCG and GnRH Agonist on Thawed Modified Natural Cycle Embryo Transfer
Impact of dual trigger using recombinant human chorionic gonadotropin (HCG) and gonadotropin-releasing hormone (GnRH) agonist on thawed modified natural cycle outcomes: an open-label multi-center randomized controlled trial.
- Trial name
- NCT07269392
- Testing
- GnRH agonist
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Poliomyelitis
Safety and Immunogenicity of a New Inactivated Poliovirus Vaccine in Infants
A new inactivated polio vaccine based on attenuated poliovirus strains was developed to transfer the technology to manufacturers in low- and middle-income countries.
- Trial name
- NCT01709071
- Testing
- IPV, Low dose Sabin-IPV, Low dose adjuvanted Sabin-IPV
- Where
- 7 sites in Poland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Pauline Verdijk
Postoperative Pain
Total Knee Replacement TIVA With Robotic Arm Assisted
Total knee replacement (TKR) is a commonly performed surgical procedure, and is associated with moderate to severe acute postoperative pain.
- Trial name
- NCT04002271
- Testing
- Propofol, Sevoflurane, Spinal anaesthesia
- Where
- 2 sites in Hong Kong
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Hong Kong
TMJ Disc Disorder
Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials
comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.
- Trial name
- NCT06441279
- Testing
- intra-articular injection with Platelet lysate (PL)., intra-articular injection with Hyaluronic Acid.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Maternal Infection During Pregnancy (Diagnosis), Neonatal Infection
Immediate Versus Delayed Induction in Term-PROM Using or Not Antibiotic Prophylaxis
The primary aim of this study is to determine if antibiotics combined with immediate induction can significantly reduce the rate of maternal and neonatal infection compared with immediate induction alone in women presenting with…
- Trial name
- NCT02985086
- Testing
- Cefoxitin, oxytocin/misoprostol
- Where
- 2 sites in Portugal
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Hospital de Santa Maria, Portugal
Labor Pain, Anxiety
Alexander Technique on Labor Pain and Anxiety
This study will examine the effect of the Alexander Technique on labor pain and anxiety during labor. This study is designed as a randomized controlled experimental study.
- Trial name
- NCT06263894
- Testing
- Experimental group
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Marmara University
Colon Cancer
Impact of a Mailed Educational Reminder on Fecal Occult Blood Testing (FOBT): A Randomized Controlled Trial
The purpose of our randomized controlled trial is to determine whether mailed educational reminders would increase fecal occult blood test (FOBT) card return rates and, therefore, improve patient compliance with colonrectal…
- Trial name
- NCT00534053
- Testing
- Mailed Educational Reminder
- Where
- United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Emotion Regulation, Depression
JoyPop Mobile Mental Health App With Transitional-Aged Youth
New challenges, stressors, and a loss of support often accompany the transition from adolescence to adulthood. Not surprisingly, transitional-aged youth (TAY) between the ages of 18-25 experience some of the highest rates of…
- Conditions
- Emotion Regulation, Depression, Anxiety, Stress
- Trial name
- NCT06239545
- Testing
- Usual Practice + JoyPop
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Chronic Periodontitis
Effect of Ashwagandha on Salivary Antioxidant and Serum c Reactive Protein in Chronic Generalized Periodontitis
Periodontal disease is an immune-inflammatory disease which consists of connective tissue breakdown, loss of attachment, and alveolar bone loss.In normal physiology, there is an equilibrium maintained between reactive oxygen…
- Trial name
- NCT03533972
- Testing
- Ashwagandha
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Healthy
The Influence of Acute Static Stretching on the Ankle Joint-position Sense of Soccer Players
The aim of this study isto investigate the influence of acute static stretching on the ankle joint position sense of soccer players.
- Trial name
- NCT06320977
- Testing
- Static Stretching
- Where
- Portugal
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Fernando Pessoa
Female Dyspareunia
A Study of Participants Ages 21-65 Diagnosed With Dyspareunia and the Effects of Low Intensity Shockwave Treatment
Dyspareunia is defined as a complaint of persistent or recurring pain or discomfort associated with attempted or complete vaginal penetration e purpose of this study is to determine the effectiveness of low intensity shockwave…
- Trial name
- NCT05806203
- Testing
- Low intensity shockwave treatment to pelvic floor region plus typical physical therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SoftWave Tissue Regeneration Technologies
Attention-Deficit/Hyperactivity Disorder
The Effects of Cannabigerol on Attention-Deficit/Hyperactivity Disorder
The goal of this clinical trial is to evaluate the effects of Cannabigerol (CBG) on indicators of Attention-Deficit/Hyperactivity Disorder (ADHD) in a sample of participants indicating/reporting symptoms associated with ADHD.
- Trial name
- CBG (NCT06115603)
- Testing
- Cannabigerol
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
FRAILTY
FRED Exergame Including Biofeeback Supervision
A pilot six-week randomised controlled trial was carried out introducing biofeedback with physiological constants as follows: systolic blood pressure, diastolic blood pressure, heart rate and blood oxygen saturation in the…
- Trial name
- NCT03425227
- Testing
- FRED EXERGAME
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Begoña Garcia Zapirain
Fissure, Dental, Adhesion
Randomized Clinical Trial of Fissure Sealants Comparing Universal Adhesive With Etch-And-Rinse Adhesive After 24 Month
Objective: This randomized, controlled clinical study aimed to evaluate the performance of one universal adhesive applied with etch-and-rinse or self-etch strategy and one etch-and-rinse adhesive on fissure sealant retention over…
- Trial name
- NCT04837469
- Testing
- fissure sealant application
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Discolored Teeth
Effect on Periodontal Markers by Bleaching Intracoronal Technique
OBJECTIVES: The aim of this clinical randomized, double-blind clinical study was to assess the markers levels of RANKL IL-1B and OPGL, involved in the external cervical resorption as a primary outcome, and change color…
- Trial name
- BLEIC (NCT02718183)
- Testing
- Hydrogen Peroxide 35% (Opalescence Endo - Ultradent, USA), carbamide peroxide 37% (Whiteness Superendo, FGM, Brazil).
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Diabetes Mellitus
A Clinical Trial Assessing the Impact of Inhaled Insulin on Glucose Disposition
To assess the impact of inhalation of insulin on glucose disposition in patients with type 1 diabetes
- Trial name
- NCT00287066
- Testing
- Inhaled Human Insulin, Regular Human Insulin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
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