Clinical trials: Randomized Clinical Trial
Ovarian Stimulation
Conventional Ovarian Stimulation vs. Single Injection Stimulation of Corifollitropin Alfa in Oocyte Donor
This study aims to study the efficiency of using a single injection of Corifollitropin alfa for ovarian stimulation by initiating administration late and without further administration of follicle-stimulating hormone after the…
- Trial name
- TAIL (NCT03939403)
- Testing
- Time of administration of Corifollitropin Alfa
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Opioid-Induced Bowel Dysfunction, Constipation
The Influence of Tramadol on Opioid-induced Bowel Dysfunction
Tramadol is a weak opioid and widely used to treat moderate to severe pain. Stronger opioids are known to inhibit gastrointestinal motility and secretion, however the effects of tramadol on gastrointestinal function remains less…
- Trial name
- NCT06385561
- Testing
- Tramadol
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asbjørn Mohr Drewes
Constipation
Fiber Regimens for Constipation Symptoms
The objective of the current study is to compare the effects of bowel recipe with psyllium on symptoms associated with constipation.
- Trial name
- constipation (NCT03845673)
- Testing
- Psyllium, Bowel recipe
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Jaw, Edentulous, Partially
Fully Guided Versus Conventionally Guided Implant Placement by Dental Students
Patients where placement of a single implant will be treated by senior dental students under close supervision of experienced spcialists.
- Trial name
- NCT04546269
- Testing
- Fully-guided vs. conventionally guided implant placement
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pediatric Cardiac Arrest (Simulated)
Examining the Effect of a Scripted Debriefing on Resuscitation Performance in Pediatrics
The investigative team's purpose for conducting this research is to improve effective and efficient translation and implementation of evidence based advanced life support practice to providers of care for children.
- Trial name
- EXPRESS (NCT01682629)
- Testing
- Debriefing Script, High Physical Realism Simulation
- Where
- Canada
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Anesthesia, Local
Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications
This Randomized study was designed to assess and compare the effect of two analgesic premedications (Ibuprofen BP 100 mg/5 ml and Paracetamol 200 mg/5ml.) on the anesthetic efficacy of buccal infiltration in vital pulpotomy of…
- Trial name
- NCT03423329
- Testing
- Brufen, Cital
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Full Spectrum
A Self-controlled Study of the Effect of Partial Spectral Absence of Visible Light on the Pupil
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by…
- Trial name
- NCT06501131
- Testing
- full-spectrum light exposure, specific spectrum absence light exposure
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Skin Wrinklings
Regenarative Treatment of Periocular Wrinkles With PDRN
This randomized clinical trial aims to compare two application techniques-needling (intradermal needling) and microneedling-for the delivery of an active-ingredient formulation containing 0.2% polynucleotides (PDRN), 2%…
- Trial name
- NCT07280637
- Testing
- Intradermal injection, Micro needling
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Dementia, Oral Hygiene
Oral Health, Bite Force and Dementia
Study aims: The primary aim is to identify influencing variables on oral hygiene / oral health and bite force in patients with dementia.
- Conditions
- Dementia, Oral Hygiene, Chewing Problem
- Trial name
- OrBiD (NCT03775772)
- Testing
- Oral Health, Bite Force
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Herpes Genitalis
Safety and Efficacy Study of Herpes Simplex Virus Type 2 (HSV-2) Therapeutic DNA Vaccine
The purpose of this trial is to evaluate the safety and efficacy of a therapeutic DNA vaccine in adults with symptomatic herpes simplex virus type 2 (i.e., genital herpes).
- Trial name
- HSV-2 (NCT02837575)
- Testing
- VCL-HB01, Phosphate-buffered saline
- Where
- 15 sites in United States
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Vical
Scoliosis, Adolescent Scoliosis
The Effectiveness of Different Exercises in Scoliosis
The aim of this study is to examine the effectiveness of stabilization exercises integrated with Schroth exercises on quality of life, trunk rotation angle, body awareness and sleep quality in young people with scoliosis.
- Trial name
- NCT06716957
- Testing
- Schroth exercise, Dynamic Stabilization exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Healthy
Beta-glucan, Product Claims and Satiety
This is a digital clinical trial to investigate satiety and consumer preference in responses to three test breakfast bars with varying level of dietary fiber, beta-glucan, and product packages (with or without product claims) in…
- Trial name
- NCT04740112
- Testing
- Foods with beta-glucan from oats and barley
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- General Mills
Jawline Contour Deficit
A Clinical Trial to Evaluate the Efficacy and Safety of LANLUMA V to Improve Jawline Contour Deficit
A Multi-center, Randomized, No-treatment Controlled, Evaluator-blinded, Superiority Clinical Trial to Evaluate the Efficacy and Safety of LANLUMA V to Improve Jawline Contour Deficit
- Trial name
- NCT06391580
- Testing
- Poly-L-lactin Acid (PLLA) Based Facial Injectable
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sinclair Pharmaceuticals Limited
Infants
Application Evaluation of Newborn Home Skin Care Management System Under the Service of "WeChat Platform+Health Care"
Through the establishment of the newborn home skin care management system under the service of "WeChat platform+health care", the investigators focus on the common skin problems of newborns at home, push health education…
- Trial name
- NCT06544096
- Testing
- intervention group (WeChat platform + healthcare), control group (routine health education)
- Where
- China
- Volunteers
- 692 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Potential Abnormality of Glucose Tolerance, Appetitive Behavior
Acute Effect of Crocus Sativus on Postprandial Glycemia
This study investigated the effects of two different doses of Crocus Sativus in glucose beverages on glycemic responses.
- Conditions
- Potential Abnormality of Glucose Tolerance, Appetitive Behavior, Blood Pressure
- Trial name
- NCT05484362
- Testing
- D-Glucose beverage as reference food, 15mg of Crocus Sativus as beverage, 30mg of Crocus Sativus as beverage
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Hip Arthritis, Total Hip Arthroplasty (THA)
Randomized Controlled Trial of Total Hip Arthroplasty
The purpose of this study is to compare the effect of total hip arthroplasty and conservative treatment to hip pain, to activities of daily life and to the quality of life in patients with hip osteoarthritis.
- Trial name
- NCT05093361
- Testing
- Total Hip Arthroplasty, Physical Therapy
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Alveolar Cleft
Alveolar Cleft Grafting by Double Iliac Bone Blocks Versus Iliac Spongy Bone From Anterior Iliac Crest
Reconstruction of Alveolar Cleft Using Double Iliac Corticocancellous Blocks in comparison with the gold standard technique ( cancellous bone ) both from anterior iliac crest.
- Trial name
- NCT05283005
- Testing
- Grafting of the alveolar cleft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
GERD
A Study to Compare PK and Safety of CKD-381 and D026 in Healthy Male Subjects
A Study to compare pharmacokinetics and safety of CKD-381 and D026 in healthy male subjects
- Trial name
- NCT03444402
- Testing
- CKD-381(formulation I), CKD-381(formulation II), D026(Nexium 40mg)
- Where
- South Korea
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Psychological Distress, Depressive Symptoms
Group CA-CBT Intervention to Reduce Psychological Distress of Earthquake Survivors
Earthquakes in Türkiye cause survivors to develop serious and prolonged mental health issues and adapted versions of cognitive behavioral therapy has proven to be successful in addressing these concerns.The main goal of this…
- Conditions
- Psychological Distress, Depressive Symptoms, Well-Being, Psychological
- Trial name
- CARED-ACT (NCT06189937)
- Testing
- Culturally Adapted Cognitive Behavioral Therapy (CA-CBT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Koç University
Tetanus, Diphtheria
A Study to Evaluate the Safety and Efficacy(Immunogenicity) of GC3111 in Healthy Adults
The purpose of this study is to evaluate safety and efficacy (immunogenicity) of a single dose of GC3111 versus Boostrix® vaccine among healthy adults in 19-64 years of age.
- Conditions
- Tetanus, Diphtheria, Whooping Cough
- Trial name
- NCT04238975
- Testing
- GC3111 vaccine, Boostrix® vaccine
- Where
- South Korea
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Green Cross Corporation
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