Clinical trials: Randomized Controlled Trial
Inactivity
Effectiveness of a Web-based, Computer-tailored, Pedometer-based Physical Activity Intervention for Adults: a Cluster-randomized Controlled Trial
The present study used a cluster-randomized controlled trial to evaluate the effects of a computer-tailored, pedometer-based Physical Activity (PA) intervention delivered through the Internet.
- Trial name
- NCT02080585
- Testing
- Physical Activity advice.
- Where
- Belgium
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University Ghent
Tooth Stain
A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal
The whitening action of an investigative hydrogen peroxide/sodium fluoride containing mouth rinse will be evaluated through stain removal using mean Lobene Stain Index over 14 days compared to a currently marketed hydrogen…
- Trial name
- NCT02151058
- Testing
- Colgate® Regular Cavity Protection, Experimental Mouth Rinse, Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
HIV
Randomized Control Trial of Shang Ring Versus Forceps-guided Adult Male Circumcision in Southwestern Uganda.
Adult male circumcision (AMC) can reduce the incidence of HIV transmission by 40-60% in sub-Saharan Africa (SSA). The World Health Organisation and Joint United Nations Programme on HIV/AIDS advocate AMC for the reduction of HIV…
- Trial name
- NCT01757938
- Testing
- Shang Ring Guided Circumcision, Forceps Guided Circumcision
- Where
- Uganda
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Quality of Life, Wellness
Effects of Wellness Coaching on Quality of Life and Wellness in Oncology Nurses
This clinical trial will test individual wellness coaching for 44 nurses who provide cancer care. Wellness means balance across physical, emotional, social, and other areas of life.
- Trial name
- NCT07889258
- Testing
- Individual Wellness Coaching
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pneumonia, Pneumococcal
Immunogenicity and Safety of 23-Valent Pneumococcal Polysaccharide Vaccine in Healthy Volunteers Aged 2 Years and Above
The purpose of this study is to evaluate Immunogenicity and safety of 23-Valent Pneumococcal Polysaccharide Vaccine in healthy volunteers aged 2 Years and above.
- Trial name
- NCT04278248
- Testing
- 23-Valent Pneumococcal Polysaccharide Vaccine
- Where
- China
- Volunteers
- 1,940 people, healthy volunteers welcome
- Sponsor
- Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd
Physical Inactivity
Makoyoh'Sokoi - The Wolf Trail Program Expansion Project - Supporting Indigenous Women to Celebrate Good Health
During the MKS+ program participants complete health education modules that expose them to health information, a substantial portion of which relate to healthy nutrition and prevention, and on occasion to local healthcare…
- Trial name
- MKS+ (NCT05362435)
- Testing
- Physical activity-based wellness programs
- Where
- 7 sites in Canada
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Immediate Dental Implants
Accuracy in Computer Guided Versus Free Hand Immediate Implantation
Patients with hopeless teeth in the esthetic area requiring immediate implant restoration will be recruited to the study. Patients will be divided into two groups; a group will receive immediate implants placed using CAD/CAM…
- Trial name
- RCT (NCT03281148)
- Testing
- Computer guided implant insertion group, Free hand implant insertion group
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Furcation Defects, Open Flap Debridement
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
The reduced rate of success experienced in the treatment of Furcation involvement (FI) seems to result from the incomplete removal of subgingival plaque and calculus in the interradicular area owing to the peculiar anatomy of the…
- Conditions
- Furcation Defects, Open Flap Debridement, Periodontal Diseases
- Trial name
- NCT06025955
- Testing
- minimally invasive non- surgical therapy, open flap debridement
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pedophilia, Hebephilia
Talking for Change: Secondary Prevention of Child Sexual Abuse Perpetration
The goal of this patient preference randomized controlled trial is to investigate the efficacy of Talking for Change (TFC), an intervention for the secondary prevention of child sexual abuse and exploitation (CSA) perpetration.
- Conditions
- Pedophilia, Hebephilia, Child Sexual Abuse, Program Evaluation
- Trial name
- NCT07001735
- Testing
- Talking for Change Group Psychotherapy, Healthier Me: Managing Risk and Stress in Everyday Life
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Iron-deficiency
Oral Lactoferrin Versus Iron Supplementation During Pregnancy
Iron deficiency anemia (IDA) is the condition in which there is anemia due to a lack of iron. The oral route is preferred to the parenteral route to replace iron stores [Sharma JB; et al., 2004].
- Trial name
- NCT03542825
- Testing
- Lactoferrin, Iron Supplement, Chelates, Iron
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South Valley University
COVID - 19
Safety and Immunogenicity of a Chimeric Recombinant Covid19 Vaccine SpiN-Tec MCTI UFMG
SpiN-Tec MCTI UFMG will be used as a vaccine booster against COVID-19 and will be evaluated using the active comparator, a vaccine approved by ANVISA (Brazilian Health Regulatory Agency).
- Trial name
- SpiN-Tec-001 (NCT07134725)
- Testing
- SpiN-Tec MCTI UFMG, Active Comparator: Covishield® vaccine, Active Comparator: Comirnaty® vaccine
- Where
- Brazil
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Cardiometabolic Diseases
Sustainable Diets and Cardiometabolic Health
This study aims to investigate the effects of sustainable diets on traditional and novel cardiometabolic risk factors. The primary objective is: To test the effects of a sustainable diet on traditional cardiometabolic risk…
- Trial name
- PlanetDiet (NCT07189676)
- Testing
- Dietary advice (PHD), Dietary advice (Ovo-lacto-vegetarian diet), Dietary advice (control)
- Where
- Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Amblyopia, Strabismus
Attention-based Binocular Training for Impaired Stereopsis (BRAVE)
This study evaluates a novel attention-based binocular visual search training paradigm designed to improve stereopsis (stereo vision) in individuals with impaired binocular vision.
- Conditions
- Amblyopia, Strabismus, Anisometropia, Binocular Vision Abnormalities
- Trial name
- BRAVE (NCT07803458)
- Testing
- Attention-Guided Dichoptic Visual Search Training, Zero-Disparity Dichoptic Visual Search Task
- Where
- 2 sites in Hong Kong
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre for Eye and Vision Research
PTSD
Prevention of Combat-related PTSD Using Attention Bias Modification (ABM): A Randomized Controlled Trial
Military deployment to combat zones involves exposure to trauma at a higher than average rate and therefore presents a unique opportunity to study predisposing factors to posttraumatic stress reactions and test strategies…
- Trial name
- NCT01723215
- Testing
- Active ABMT8, Active ABMT4
- Where
- Israel
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Pain, Opiate
Intensive Cryotherapy in the Emergency Department for Acute Musculoskeletal Injuries
Acute musculoskeletal (MSK) injuries, including strains, sprains or contusions, are a common reason patients seek emergency care. Pain control is an essential component of treatment.
- Conditions
- Pain, Opiate, Emergency
- Trial name
- NCT02720315
- Testing
- Intensive cryotherapy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
Other Endosseous Dental Implant Failure
Effect of Immediate Placement and Loading of Compressive Versus Conventional Implants
The current study aims to compare immediate placement and loading of compressive versus conventional dental implants after atraumatic extraction regarding the effectiveness, bone resorption and survival of each of them.
- Trial name
- Implants (NCT07601347)
- Testing
- Immediate implant placement and loading
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahmed Nagi Alghandour
Lateral Ankle Instability
Modified Brostrӧm Procedure With and Without Possible Arthroscopy for Lateral Ankle Instability
This study is to show that the investigators believe the Modified Brostrӧm Procedure (MBP) can be completed without a routine ankle arthroscopy.
- Trial name
- NCT02470338
- Testing
- MBP plus arthroscopy (Group A), MBP alone (Group B)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Edna Rath
Hypersensitivity Dentin
Pain Control in Dentin Hypersensitivity in Patients With MIH
This study aims to evaluate the effectiveness of different protocols in controlling dentin hypersensitivity in patients with teeth affected by MIH.
- Trial name
- NCT04268238
- Testing
- Hygiene Guidance, Sealant Application, Low Level Laser Application
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Obesity
Anti-obesity Treatment by Loading in Adult Subjects
Obesity related ailments, such as cardiovascular diseases (CVD) and metabolic disorders are major causes of death in the Western World.
- Trial name
- ATLAS (NCT04697238)
- Testing
- Weight vest
- Where
- Sweden
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Immunology
A Trial of SHR-2173 in Healthy Volunteers
The purpose of this study is to assess safety, PK, Pharmacodynamic and immunogenicity profile of a single dose of SHR-2173 in healthy participants
- Trial name
- NCT07390747
- Where
- Australia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Atridia Pty Ltd.