Clinical trials: Randomized Controlled Trial (RCT)
Sleep
Evening Screen Content and Sleep Architecture in Older Adults: Crossover RCT
Title The Effect of Evening Technology Use with Calming vs. Exciting Content on Sleep Architecture in Older Adults: A Crossover Randomized Controlled Trial Background The study explores how evening use of digital devices with…
- Trial name
- NCT07001514
- Testing
- Calming digital content, Exciting Digital Content, Non-digital book reading
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Dupuytren Contracture
Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF
Aim: Clinical RCT comparing functional results and recurrence rate following enzymatic treatment vs. needle aponeurotomy. Materials and methods: 30° or more contracture of only one metacarpophalangeal (MCP) joint contracture of…
- Trial name
- NCT02647619
- Testing
- Xiapex, Needle aponeurotomy
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Dietary Habits
SMS Messages to Increase Child Egg Consumption, a C-rct in Nepal
Eggs are well-known to be a balanced source of protein, energy, fatty acids, and micronutrients and increasingly identified as an opportunity to improve nutrition of poor populations.
- Trial name
- NCT03926689
- Testing
- SMS messages, Standard SII SBCC
- Where
- Nepal
- Volunteers
- 3,301 people, healthy volunteers welcome
- Sponsor
- Helen Keller International
Generalized Anxiety, Stress Disorder, Posttraumatic
CBT for Anxiety Sensitivity vs. Disorder-specific CBT: An RCT
Adults with high anxiety sensitivity (AS) and a mental health diagnosis of anxiety, depression, or posttraumatic stress will be recruited and will be randomly assigned to either transdiagnostic cognitive behavioural therapy (CBT)…
- Conditions
- Generalized Anxiety, Stress Disorder, Posttraumatic, Social Anxiety, Major Depression
- Trial name
- NCT03015285
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Obesity, Hypertension
Postpartum Weight Retention
The Postpartum Weight Management Study is a true community-academic collaboration, bringing together Maternity Care Coalition (MCC) staff and the investigator, Dr.
- Conditions
- Obesity, Hypertension, Depression
- Trial name
- NCT02867631
- Testing
- 6 week challenge with 1 year of home visits: health texting, in home exercise supports, social support, healthy eating and feeding classes
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Growth Disorders, Dietary Exposure
Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns
This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years.
- Conditions
- Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal
- Trial name
- NCT06329388
- Testing
- TruHeight Growth Protein Shake
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TruHeight Vitamins
Disaster Medicine Education and Preparedness Among Medical Students, Disaster Medicine Knowledge and Skills Training for Pre-clinical Medical Students
Disaster Medicine Training for Pre-Clinical Medical Students at the University of Tripoli, Libya
Libya has faced several natural and human-made disasters in recent years, highlighting the need to strengthen disaster preparedness and response capacity.
- Conditions
- Disaster Medicine Education and Preparedness Among Medical Students, Disaster Medicine Knowledge and Skills Training for Pre-clinical Medical Students, Disaster and Emergency Medicine Education and Preparedness Among Pre-clinical Medical Students
- Trial name
- DM-Course RCT (NCT07293572)
- Testing
- Structured Disaster Medicine Training Program
- Where
- Libya
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Tripoli
Postpartum Depression, Postpartum Anxiety
Online 1-Day CBT-Based Workshops for Preventing Postpartum Depression
To conduct a randomized controlled trial (N=408) examining the impact of an online cognitive behavioural therapy (CBT)-based workshop on rates of postpartum depression (i.e., EPDS scores at 2-months postpartum) when added to…
- Trial name
- NCT05753176
- Testing
- Online 1-Day Cognitive Behavioural Therapy-Based Workshop
- Where
- Canada
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- McMaster University
Chronic Pain, Mild Cognitive Impairment
Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT
The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and early cognitive decline.
- Trial name
- NCT07785648
- Testing
- Feeling of Being, Health Enhancement Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Women Who Are Aged 18-49 Years, Able to Read, Write
Reducing Endocrine-Disrupting Chemical Exposure in Reproductive-Age Women: A Pender Model-Based RCT
Abstract Background: Endocrine-disrupting chemicals (EDCs) are widely encountered in daily life and may adversely affect reproductive health.
- Conditions
- Women Who Are Aged 18-49 Years, Able to Read, Write, Voluntarily Agree to Participate in the Study
- Trial name
- NCT07773233
- Testing
- Intervention Group
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Harran University
Family Members, Health Care Providers
Family Participation in CICU Rounds: RCT
This is a single-center, unblinded, pragmatic randomized controlled trial comparing family participation in cardiac ICU team rounds with usual care. We will recruit 112 family members.
- Conditions
- Family Members, Health Care Providers, Engagement, Patient
- Trial name
- FAM-CICU (NCT05528185)
- Testing
- Direct participation of the family member in the daily rounds
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Mental Health, Social Isolation
A Mixed Methods Randomized Controlled Trial Evaluating the Hans Kai Program
The Hans Kai trial is a mixed methods randomized controlled trial evaluating the effectiveness of the peer-led health promotion Hans Kai program for Canadian adults with or without chronic health conditions.
- Conditions
- Mental Health, Social Isolation, Loneliness, Health-Related Behavior
- Trial name
- NCT03949725
- Testing
- Hans Kai Program
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Anovulatory Infertility Related to Polycystic Ovary Syndrome
Strategies for Ovulation Induction in Anovulatory Infertile Patients With PCOS
Anovulatory infertility is a common feature of the polycystic ovary syndrome (PCOS). Even if several first-step treatments have been proposed for anovulatory infertile PCOS patients, very few data are available in literature…
- Trial name
- NCT00461643
- Testing
- Clomiphene citrate, metformin, metformin plus clomiphene citrate, gonadotropins
- Where
- 3 sites in Italy
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Musculoskeletal Diseases or Conditions
Wadey RCT MSK Short Case Simulations With FMED
Study Agent/ Intervention/ Procedure The educational tool consisted of 20 short (MSK) case simulations of 15 minutes duration reflecting conditions of the upper extremity; lower extremity; spine; trauma and MSK infections were…
- Trial name
- NCT05914922
- Testing
- Educational Tool
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Cognitive Function, Mood Disorders
RCT on the Neurobehavioral Effects of Fruits and Vegetables in Shanghai Children
This project proposal outlines a randomized-controlled trial (RCT) aimed at evaluating the effects of increased fruit and vegetable (F\&V) intake on cognitive performance, attention, and mood in Chinese children aged 7-11…
- Conditions
- Cognitive Function, Mood Disorders, Attention-deficit
- Trial name
- NCT06560359
- Testing
- F&V, No F&V
- Where
- China
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Fudan University
Non-Small Cell Lung Carcinoma, Compliance Behavior
Patient Navigation for Lung Cancer Screening in an Urban Safety-Net System
The study proposes to evaluate a patient navigation intervention among a sample of 446 individuals referred for CT-based lung cancer screening in an urban safety-net setting.
- Conditions
- Non-Small Cell Lung Carcinoma, Compliance Behavior, Prevention Harmful Effects
- Trial name
- NCT02758054
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Contraception, Hypercoagulability
Comparison of Coagulation Profiles Between Zoely and Minidoz: RCT
The purpose of this study is to compare the effects of Zoely® and Minidoz® on hemostatic profiles
- Trial name
- NCT03531437
- Testing
- 1.5 mg estradiol and 2.5 mg nomegestrol acetate, 15 µg ethinylestradiol and 60 µg gestodene
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Caries
The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children.
The aim of this RCT was to verify the caries preventive efficacy of toothpastes containing biomimetic hydroxyapatite (H.A.) complex in children compared to traditional fluoridated toothpastes.
- Trial name
- NCT04906291
- Testing
- Toothpaste use
- Where
- Italy
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Occupational Stress
Feasibility of Stress Management Education Delivered Via Virtual Classroom in Nursing Homes: a Pilot Study of a RCT
The aim of this cluster-randomised pilot study is to assess the feasibility of a remote stress management programme to reduce occupational stress in healthcare workers in specialised care units of nursing homes.
- Trial name
- AGIT-RESTS-1 (NCT06727682)
- Testing
- Stress management
- Where
- 4 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GCS CIPS
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06831006)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand