Clinical trials: Randomized Controlled Trials
Odontologic Disorders
Patient Reported Experience Measures Following a First Remote Orthodontic Consultation : a Randomized Controlled Trial
The objective of this present randomized controlled trial was to investigate patient's and practitioner's Reported Outcomes Measures (PROMs) following a first standard face-to-face consultation versus a first orthodontic…
- Trial name
- NCT05646277
- Testing
- e-Consultation, Consultation
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Rhinosinusitis (Diagnosis)
Silver Nanoparticle Investigation for Treating Chronic Sinusitis
Chronic rhinosinusitis is a highly prevalent disease resulting in high economic burden. Effective therapeutic options are needed. Rhinosinusitis-related biofilms are a likely contributor to recalcitrant disease.
- Trial name
- SNITCH (NCT03243201)
- Testing
- Colloidal silver nanoparticles, Purified Water
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Infertility, IVF
Addition of Dydrogesterone to the Luteal Phase Support After Fresh Embryo Transfer
Randomized controlled study, open label to compare effectiveness of addition of dydrogesterone 20mg to the standard luteal phase support treatment after fresh embryos transfer.
- Trial name
- NCT04408144
- Testing
- Dydrogesterone 10mg Oral Tablet
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Laniado Hospital
Ankylosing Spondylitis, Work Productivity
Work Productivity and Social Activities In Patients With Ankylosing Spondylitis
The aim of this study is to evaluate the relationship between decrease in work productivity and social activities in patients with Ankylosing Spondylitis (AS) with disease activity, depression and quality of life together with…
- Trial name
- NCT04749537
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Dental Caries, Gingivitis
Antimicrobial Efficacy of Biogenic Gold Nano Particle From Pelargonium Graveolens Leaves Extract Mouthwash for Children
The study is randomized controlled trial ... The null hypothesis of the present study is that there is no antibacterial efficacy of gold nanoparticles of pelargonium graveolens mouthwash against Streptococcus mutans and Candida…
- Conditions
- Dental Caries, Gingivitis, Periodontitis
- Trial name
- GNPG (NCT05816512)
- Testing
- Gold Nano particle from Pelargonium Graveolens Mouthwash, Chlorhexidine gluconate mouthwash .
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ahmed Yousif Mahdi
COVID-19 Pandemic, Simulation of Physical Illness
COVID-19 Simulation Education on Nursing Students
This study aims to determine the effect of simulation education as an approach to patients with COVID-19 on nursing students' perception and fear of the COVID-19 disease.
- Trial name
- NCT05576636
- Testing
- Simulation training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Palliative Care, Generative Artificial Intelligence
Patient Aid for Theory-Driven Health Communication (PATH): Translating Goal-Power Theory Into an Instrument and Generative AI Support for Palliative Care Communication
The goal of this clinical trial is to learn whether an artificial intelligence (AI)-supported communication tool can help improve communication between people receiving palliative care and their healthcare providers.
- Conditions
- Palliative Care, Generative Artificial Intelligence, Natural Language Processing (NLP)
- Trial name
- NCT07692711
- Testing
- NurseChat+
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Gestational Diabetes, Continuous Glucose Monitoring
The Effect of Continuous Glucose Monitoring on Glycemic Control and Pregnancy Outcomes in Gestational Diabetes Mellitus
The purpose of this study is to determine if Continuous glucose monitoring improves glycemic control and pregnancy outcomes of Gestational Diabetes Mellitus
- Trial name
- NCT03955107
- Testing
- Continuous Glucose Monitoring System
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Nurse, Attention
Effects of Aerobic Exercise Training on Nurses' Sleep Quality, Fatigue, Attention and Cortisol Profile
Shift work in nursing has been found to result in sleep disruption and sleep deprivation, and in sleepiness or fatigue at work. Slow reaction, insufficient attention and poor judgement often come with increased fatigue, which…
- Conditions
- Nurse, Attention, Aerobic Exercise, Sleep Quality
- Trial name
- NCT03759509
- Testing
- aerobic exercise
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Retrograde Bladder Fill
A Randomized Controlled Trial on the Effect of Retrograde Partial Bladder Fill on Time to Discharge and Overall Medical Staff Satisfaction
This study is a randomized controlled trial on the effect of retrograde partial bladder fill on time to discharge in patients who have had urological surgery for BPH, and whether it affects overall medical staff satisfaction.
- Trial name
- NCT04309032
- Testing
- retrograde bladder filling with 0.9% normal saline 250cc prior to removal of foley catheter
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Influenza
Evaluation of the Safety and Immunogenicity of a Recombinant Trivalent Nanoparticle Influenza Vaccine With Matrix M-1 Adjuvant (NanoFlu)
This was a Phase 1/2, randomized, observer-blinded, active-controlled trial to assess the Safety and Tolerability of a Recombinant Trivalent Nanoparticle Influenza Vaccine (Tri-NIV) with Matrix M1™ Adjuvant in Healthy Older…
- Trial name
- NCT03293498
- Testing
- NanoFlu, Fluzone HD - Day 0, Fluzone HD - Day 21
- Where
- 3 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Novavax
Healing Wound
Wound Healing with Hyaluronic Acid After Alveolar Ridge Preservation
After tooth extraction, shrinkage of the bone is expected after 6 months. These changes may hamper dental implant placement and compromise soft tissue aesthetics.
- Trial name
- NCT04467736
- Testing
- Gengigel Forte©
- Where
- Belgium
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Inflammatory Bowel Diseases
Preoperative Oral ImmunoNuTrition to Improve Surgical Outcomes for IBD Patients (PINT)
The central focus of this trial is to understand the effectiveness of Preoperative Immunonutrition (PINT) in improving surgical outcomes for patients with inflammatory bowel disease (IBD).
- Trial name
- PINT (NCT03333148)
- Testing
- Nestle IMPACT Immunonutrition, Arm B- Standard of Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Otorhinolaryngologic Diseases
Evaluation of Office-Based Sheathed Flexible Nasopharyngoscopy
The processing of standard flexible nasopharyngoscopes is a time-consuming and costly process. The goal of this study is to determine the efficiency and cost-effectiveness of sheathed flexible endoscope in an office setting.
- Trial name
- NCT01669278
- Testing
- Endosheath
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Blood Pressure
Health Effects of Indoor Air Filtration in Healthy Chinese Adults
This study aims to detect serum metabolite changes, as well as other health indicators with the intervention of air purifiers on a randomized, crossover, double-blind trial.
- Trial name
- NCT02712333
- Testing
- Air Purifiers
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fudan University
Tuberculosis
Randomized Controlled Trial of Percutaneous and Intradermal BCG Vaccination.
An open label, randomized, controlled, equivalency trial to compare the efficacy of the percutaneous route of administration with the intradermal route of administration of Japanese (Tokyo) 172 BCG, in the prevention of…
- Trial name
- NCT00242047
- Testing
- Japanese (Tokyo) 172 Bacille Calmette Guerin (BCG).
- Where
- South Africa
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Educational Problems
The Impact of Web 2.0 Tools on Nursing Education
This research was planned experimentally to investigate the effect of teaching supported by WEB 2.0 tools on the development of WEB pedagogical content knowledge of nursing students.
- Trial name
- NCT06390449
- Testing
- Kahoot intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Healthy Children
Outdoor Science Education and Child Well-being in Primary Schools: Protocol for a Cluster Randomized Controlled Trial on Learning, Connection to Nature, Eco-anxiety, and Stress
The goal of this randomized controlled trial is to learn if an outdoor science education intervention can improve primary school students' learning and well-being when compared to an indoor classroom-based science education…
- Trial name
- Bio-Explo (NCT07147634)
- Testing
- Outdoor science education, Indoor classroom-based science education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Immunomodulation Effect
Effect of Autologous Cord Blood-mononuclear Cells Infusion on Immune Microenvironment in Infants Born Very Preterm in NICU
Multi-omics (analysis of peripheral blood immune cells subset, peripheral blood MNCs transcriptome, soluble inflammatory cytokine profile in blood and airway secretion, lung and gut microbiota, and the interaction) analysis was…
- Trial name
- NCT05087498
- Testing
- autologous cord blood mononuclear cells, normal saline
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Alveolar Ridge Enlargement
Titanium Reinforced d-PTFE Membrane Versus Collagen Membrane For Guided Bone Regeneration
After tooth extraction, shrinkage of the bone is expected with 50% reduction of alveolar width. Patients at least 3months after tooth extraction and in need of single oral implant placement in the anterior maxilla with both…
- Trial name
- NCT05426616
- Testing
- collagen membrane (Creos Xenoprotect , Nobel Biocare AB, Göteborg, Sweden), titanium reinforced d-PTFE membrane (Creos Syntoprotect , Nobel Biocare AB, Göteborg, Sweden)
- Where
- 3 sites in Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Ghent
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