Clinical trials: Randomized-controlled Trial
Hypertension, Gut Dysbiosis
The Effects of a Commercially Available Synbiotic on the Gut Microbiome and Cardiometabolic Health
The purpose of this study is to see the effect of 30 days of synbiotic vs. probiotic supplementation (usingJuice+ nutrition products) on body weight, metabolism, cardiovascular health, and gut health.
- Conditions
- Hypertension, Gut Dysbiosis, Overweight , Obesity
- Trial name
- NCT07515443
- Testing
- Synbiotic
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Southern Utah University
COVID-19
Phase II Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell) for the Prevention of COVID-19
The purpose of this double-blind, randomized, controlled study is to assess immunogenicity and safety of 202-CoV at multiple dose levels, administered as 2 injections (i.m) at 28 days apart in adult subjects 18 years of age and…
- Trial name
- NCT04990544
- Testing
- 202-CoV low adjuvant dose, 202-CoV low antigen dose, 202-CoV standard dose
- Where
- China
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Proximal Femoral Fracture, Dinamic Hip Surgery
Motion Graphic Training for Scrub Nurses in Hip Surgery
This pilot randomized controlled trial evaluates the effect of motion graphic video-based training on the performance of scrub nurse students during dynamic hip screw (DHS) surgery.
- Trial name
- NCT07701564
- Testing
- Motion Graphic Video Training, Routine Clinical Training
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Healthy
YouTube-Delivered Physical Activity Intervention
This study will be an 8-week randomized controlled trial examining the effects of a YouTube-delivered aerobic and muscle strengthening physical activity intervention on university students' physical activity, fitness, sleep…
- Trial name
- NCT04499547
- Testing
- YouTube-delivered aerobic and muscle-strengthening physical activity intervention
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Occupational Exposure to Radiation
Radioprotective Light-weight Caps in the Interventional Cardiology Setting
The primary objective of the present trial is to compare the radiation attenuation provided by XPF caps (0.5mm lead-equivalent and 0.3mm lead-equivalent) to the standard protection (fabric cap, basically no protection) as…
- Trial name
- PROTECT (NCT01620658)
- Testing
- 0.5mm XPF cap, 0.3mm XPF cap, Standard cap
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Baptist Health South Florida
Surgical Site Infection, Surgical Wound Infection
Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections
A Randomized controlled trail to To assess the efficacy of povidone-iodine wash before wound closure in preventing surgical site infections.
- Trial name
- NCT05077592
- Testing
- 10% Povidone Iodine
- Where
- Egypt
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Preterm Labor
Vaginal Progesterone Supplementation in the Management of Preterm Labor
This study evaluates the addition of vaginal progesterone in the management of preterm labor. Half of participants will receive vaginal progesterone, tocolysis and corticosteroid, while the other half will receive only tocolysis…
- Trial name
- NCT03202836
- Testing
- progesterone, Tocolytics, Steroids
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Dental Caries in Children
Supportive Caries Preventive Programme in Children Undergoing Dental General Anaesthesia
Early childhood caries is a persistent problem often leading to dental treatment under general anaesthesia (GA). Thus, this study was to investigate the preventive effect of two additional intensive oral hygiene appointments…
- Trial name
- NCT05110534
- Testing
- additional oral hygiene appointments
- Where
- Germany
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Low Back Pain, Athletic Injuries
Hamstring Viscoelasticity and Low Back Pain
Low back pain (LBP) is a prevalent issue among adolescent rowers, particularly males aged 14 to 16 years, with a high lifetime prevalence (94%) and point prevalence (65%).
- Trial name
- NCT05939609
- Testing
- Ballistic Stretching Exercise, Extender Exercise, Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Child Behavior, Child Development
Promoting Mental Health in Young Children - a Dialogue Based Approach in Kindergartens
The goal of this clinical trial is to learn if the novel Dialogue Based Early Detection (DBED) method can prevent impaired mental health in kindergarten children.
- Trial name
- PRO-DIALOG (NCT06471816)
- Testing
- Dialogue Based Early Detection, Traditional parent-teacher meeting
- Where
- 3 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Pelvic Organ Prolapse
Anterior Prolapse Repair With and Without Graft Augmentation
This is a randomized control trial comparing anterior colporrhaphy with augmentation with dermal allograft (ARCUS) to anterior colporrhaphy with a suture-based repair (native tissue).
- Trial name
- ARCUS (NCT04085952)
- Testing
- dermal graft (ARCUS repliform) for anterior colporrhaphy, suture based anterior colporrhaphy
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Iron-deficiency Anemia
Lactoferrin Supplementation and Iron Metabolism in Healthy Pregnant Women
To assess the effects of a lactoferrin supplemented formula on fetal development , iron metabolism and immunity in healthy pregnant women.
- Trial name
- NCT03122938
- Testing
- lactoferrin-supplemented formula, formula without lactoferrin supplementation
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beingmate Baby & Child Food Co Ltd .
Breastfeeding, Self-Compassion
Compassion-Based Breastfeeding Counseling and Its Effects on Self-Compassion, Mindful Breastfeeding, and Self-Efficacy
This randomized controlled trial aims to evaluate the effects of compassion-based breastfeeding counseling on self-compassion, mindful breastfeeding, and breastfeeding self-efficacy during the perinatal period.
- Conditions
- Breastfeeding, Self-Compassion, Perinatal Care
- Trial name
- COMBFED (NCT07567755)
- Testing
- Compassion-Based Breastfeeding Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gazi University
Narcotics, Recovery Quality
Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy
Laparoscopic sleeve gastrectomy is widely employed nowadays. Multimodal analgesia approach is implemented within the enhanced recovery protocol in our facility to improve participants' recovery.
- Conditions
- Narcotics, Recovery Quality, Analgesia, Bariatric Surgery
- Trial name
- NCT04285255
- Testing
- Fentanyl, Ketamine, Dexmedetomidine Injection [Precedex]
- Where
- Saudi Arabia
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Al Mashfa Medical Center
Class V Dental Caries
Clinical Evaluation of Giomer Based Injectable Resin Composite Versus Resin Modified Glass Ionomer in Class V Carious Cavities Over 18-months.
Class V carious lesions will be restored using either Resin modified glass ionomer or Giomer based injectable resin composite.The restorations will be evaluated at baseline and regular recalls of 3 months, 6 months, 12 months and…
- Trial name
- NCT05389163
- Testing
- Giomer based injectable resin composite, Resin modified glass ionomer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nursing, Students
Effectiveness of Web-based Genomic Nursing Education Intervention
There is a research gap of integrating genomics into nursing practice, education and research. Nursing students seldom use genetic-genomic data for understanding the individuality of patients and utilize this in delivering…
- Trial name
- NCT03963687
- Testing
- Standard Nursing Education Intervention, New Nursing Education Intervention
- Where
- Finland
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Misadventure During Surgical Operation, Postoperative Complications
Trendelenburg's Slide Prevention Study
The purpose of this study is to compare two cushioning materials (a gel mattress and an egg-crate foam mattress) placed beneath patients undergoing gynecologic surgery to prevent patients from sliding toward the head of the bed…
- Trial name
- SPS (NCT01068821)
- Testing
- Gel pad, Egg crate foam mattress
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Carpal Tunnel Syndrome
Treatment of Carpal Tunnel Syndrome With Dynamic Splinting
The Purpose of this study is to examine the effect of using the Carpal Tunnel Dynasplint® System on patients diagnosed with CTS in a randomized, controlled, cross-over study.
- Trial name
- NCT00558116
- Testing
- Dynamic splinting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Advanced Centers for Orthopaedic Surgery and Sports Medicine
Critical Illness, Delirium in the Intensive Care Unit
Pilot Feasibility Study of a Pragmatic Mixed-Methods Randomized Controlled Trial on a Follow-Up Bundle of Care for ICU Survivors and Caregivers
~80% of ICU survivors experience profound long-term cognitive, physical, and psychiatric impairments known as post-intensive care syndrome (PICS).
- Trial name
- IMPACT-ICU (NCT06681649)
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Queen's University
Fetal Growth Abnormalities, Fetal Weight
Impact of AI Feedback on Ultrasound Biometry Accuracy Across the Expertise Levels
Objective: To evaluate the impact of real-time AI feedback on fetal biometry accuracy and investigate the Expertise Reversal Effect-whether AI benefits diminish as user experience increases.
- Trial name
- NCT07476638
- Testing
- AI interventional group
- Where
- 3 sites in Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
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